- Reproductive tract infections research
- Urinary Tract Infections Management
- Cervical Cancer and HPV Research
- Toxoplasma gondii Research Studies
- Alcohol Consumption and Health Effects
- Gastrointestinal disorders and treatments
- Pelvic floor disorders treatments
- Gout, Hyperuricemia, Uric Acid
- Lymphoma Diagnosis and Treatment
- Herpesvirus Infections and Treatments
- Lung Cancer Treatments and Mutations
- Parvovirus B19 Infection Studies
- Oral Health Pathology and Treatment
- Viral-associated cancers and disorders
- Ovarian cancer diagnosis and treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Cancer Studies
- Diabetes Treatment and Management
- Diagnosis and treatment of tuberculosis
- Adrenal and Paraganglionic Tumors
- Endometrial and Cervical Cancer Treatments
- Colorectal Cancer Surgical Treatments
- Omental and Epiploic Conditions
- Diabetes Management and Research
- Curcumin's Biomedical Applications
National Defense Medical Center
2019-2024
Tri-Service General Hospital
2019-2024
Taoyuan Armed Forces General Hospital
2019-2024
Taipei Medical University
2018-2022
Ministry of Health and Welfare
2018
This study aimed to evaluate the adverse clinicopathologic features of oral squamous cell carcinoma (OSCC), including margin status, depth invasion, lymphovascular perineural and extranodal extension that significantly affect survival outcomes. retrospective cross-sectional included 341 patients with OSCC who underwent therapeutic surgical treatment in Taiwan. The Kaplan–Meier method was used estimate A multivariable Cox regression model associations various 5-year overall (OS) outcomes pN0...
Background Tuberculosis (TB) presents a global threat in the world and lung is frequent site of metastatic focus. A previous study demonstrated that TB might increase primary cancer risk by two-fold for more than 20 years after diagnosis. However, no large-scale has evaluated secondary cancer. Thus, we patients with or without tuberculosis using nationwide population-based dataset. Methods In cohort 1,936,512 individuals, selected 6934 among infection, based on International Classification...
Abstract Trichomonas vaginalis infection is one of the most widespread sexually transmitted infections in world. There are approximately 276 million cases worldwide. Most men remain undiagnosed and untreated because they asymptomatic. The chronic inflammation induced by persistent may increase risk developing genitourinary cancers. In this study, we aimed to investigate association between trichomoniasis benign prostate hyperplasia (BPH), cancer (PCa), bladder (BC) Taiwan. We designed a...
Approximately 25-30% of individuals worldwide are infected with Toxoplasma gondii (T. gondii), which is difficult to detect in its latent state. We aimed evaluate the association between toxoplasmosis, risk dementia, and effects antibiotics Taiwan.This nationwide, population-based, retrospective cohort study was conducted using Longitudinal Health Insurance Database containing records 2 million retrieved from Taiwan's National Research Database. Fine-Gray competing analysis used determine...
Background/Aim: Demethoxycurcumin (DMC), one of the derivatives curcumin, has been shown to induce apoptotic cell death in many human cancer lines. However, there is no available information on whether DMC inhibits metastatic activity glioblastoma cells vitro. Materials and Methods: at 1.0-3.0 μM significantly decreased proliferation GBM 8401 cells; thus, we used 2.0 for further investigation regarding anti-metastatic cells. Results: The internalized amount reached highest level after 3 h...
The glucokinase regulator gene (GCKR) is located on chromosome 2p23. It plays a crucial role in maintaining plasma glucose homeostasis and metabolic traits. Recently, genome-wide association studies have revealed positive between hyperuricemia GCKR variants adults. This study investigated this genetic Taiwanese adolescents. Data were collected from our previous cross-sectional (Taipei Children Heart Study). frequencies of various genotypes (CC, CT, TT) or alleles (C T) the intronic...
Approximately 10 percent of T1 colorectal cancer (CRC) has lymph node metastasis. In this study, we aimed to determine possible predictors for nodal involvement in order aid selection appropriate patients organ-preserving strategies.We retrospectively reviewed CRC underwent radical surgery from January 2009 December 2016, with final pathology report disclosed as lesion. The paraffin-embedded samples were achieved glycosylated proteins expression analysis by immunohistochemistry.Totally, 111...
With less than 90 reported cases to date, stercoral perforation of the colon is a rare occurrence. Stercoral ulceration thought occur due ischemic pressure necrosis bowel wall, which caused by presence stercoraceous mass. To underscore this urgent surgical situation concerning clinical presentation, treatment, and results, we present case 66-year-old man with perforation.
Key Clinical Message Adult intussusception necessitates early surgical intervention. We emphasis the significance of considering diffuse large B‐Cell lymphoma in differential diagnoses for adult intussusception, particularly colon, to ensure precise diagnosis and optimal management.
<b>Aims:</b> The first aim of the present study is to evaluate current glycemic control and characteristics overall newly diagnosed diabetes mellitus (DM) population from two cohorts (2011–2012 2014–2015). Furthermore, hemoglobin A1C (HbA1C) levels in these will be also compared HbA1C on 2013 subjects previous DM ongoing therapy. <b>Settings Design:</b> This a retrospective observational cohort study. <b>Subjects Methods: </b> All data come Nauru Diabetes Registry database Public Health...
<br>Epstein–Barr virus (EBV) infection is a common infectious disease in young adults and children. A 4-year-old boy was presented with enlarged tonsils purulent discharge. Sudden airway collapse desaturation were noted, endotracheal tube intubation performed. The laboratory data demonstrated positive results for EBV immunoglobulin M (IgM). Polyclonal B-cell activation that led to cytomegalovirus (CMV) IgM herpes simplex (HSV) also detected by the interference of heterophilic antibodies....
Abstract Background: Trichomonas vaginalis infection is one of the most widespread sexually transmitted infections in world. There are approximately 276 million cases worldwide. Most men remain undiagnosed and untreated because they asymptomatic. The chronic inflammation induced by persistent may increase risk developing genitourinary cancers. In this study, we aimed to investigate association between trichomoniasis benign prostate hyperplasia (BPH), cancer (PCa), bladder (BC) Taiwan....
Abstract Background: Recent genome-wide association studies revealed a positive between hyperuricemia and variants of the glucokinase regulator (GCKR) gene in adults. This study replicated genetic Taiwanese adolescent population. Methods: The frequencies different genotypes or alleles GCKR rs780094 rs1260326 single-nucleotide polymorphism (SNP) were compared 962 subjects (468 boys, 494 girls) with (HUA) normal uric acid (NUA) levels relative to gender. Logistic regression analysis was...
Abstract Introduction: Trichomonas vaginalis infection is one of the most widespread sexually transmitted infections in world. There are approximately 276 million cases worldwide. Most men remain undiagnosed and untreated because they asymptomatic. The chronic inflammation induced by persistent may increase risk developing genitourinary cancers. In this study, we aimed to investigate association between trichomoniasis benign prostate hyperplasia (BPH), cancer (PCa), bladder (BC) Taiwan....
Abstract Background Toxoplasma gondii ( T. ) has infected about 25–30% of individuals worldwide, and it was difficult to detect its latent status. We aimed evaluate the association between toxoplasmosis, risk dementia, effects antibiotics in Taiwan. Material methods This nationwide, population-based, retrospective cohort study conducted by using two million Longitudinal Health Insurance Database retrieved from Taiwan’s National Research Database. The Fine Gray’s competing analysis used for...