- Neuroscience and Neuropharmacology Research
- Thyroid Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Neurotransmitter Receptor Influence on Behavior
- Medical Imaging and Pathology Studies
- Lung Cancer Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Radiomics and Machine Learning in Medical Imaging
- Radiopharmaceutical Chemistry and Applications
- Radiation Dose and Imaging
- Advanced MRI Techniques and Applications
- Nerve injury and regeneration
- Cancer Diagnosis and Treatment
- Head and Neck Anomalies
- Parkinson's Disease Mechanisms and Treatments
- Neurogenesis and neuroplasticity mechanisms
- Thyroid Disorders and Treatments
- Sarcoidosis and Beryllium Toxicity Research
- Neurological disorders and treatments
- MRI in cancer diagnosis
- Salivary Gland Tumors Diagnosis and Treatment
- Pediatric Urology and Nephrology Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Sarcoma Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
Tri-Service General Hospital
2015-2025
National Defense Medical Center
2015-2025
SwissLitho (Switzerland)
2015
Changhua Christian Hospital
2015
Demonstrating a positive impact of educational programs on clinical care outcomes is challenging. We assess students' knowledge, attitudes, and behaviors as short-term integrating structured Traditional Chinese Medicine course within Western medical school. A prospective questionnaire survey was conducted among first-year second-year undergraduate students who participated in the "Introduction to Medicine" 2020. The assessed their before after completing 32-hour course. In total, 89...
Bezafibrate, a pan-peroxisome proliferator-activated receptor (PPAR) agonist, reportedly attenuated tau pathology in transgenic mouse model of primary tauopathy. Since is neuropathological hallmark Alzheimer's disease (AD), bezafibrate may be potential drug for the treatment AD. However, no study has investigated its effects AD models. Thus, we aimed to evaluate whether neuroprotective sporadic induced by streptozotocin (STZ) intracerebroventricular (ICV) injection. Rats were administered...
Abstract Recent studies revealed the risk of bullous pemphigoid (BP) in patients with diabetes mellitus (DM) taking dipeptidyl peptidase 4 (DPP‐4) inhibitors. To clarify relationship between DPP‐4 inhibitors and BP among DM, we conducted a cohort study by using National Health Insurance Research Database Taiwan from 1 January 2009 to 31 December 2015. We identified 6340 DM 25 360 who had not taken during 7‐year follow‐up period. Compared non‐DPP‐4 inhibitor group, DDP‐4 higher (adjusted...
18F-FDG PET/CT is a promising tool in detecting aortic graft infection. Present study investigated the value of dual-time-point imaging (DTPI) with delayed assessing Twenty-nine patients suspected infection were prospectively enrolled this DTPI study. Two nuclear medicine physicians read all images and achieved consensus about measurement maximal standardized uptake (SUVmax) grading image quality. The percentages SUVmax change between initial recorded as retention index (RI); sensitivity,...
This study was undertaken to address the effects of fetal mesencephalic tissue transplantation on serotonin system in a rat model Parkinson's disease (PD) while also investigating usefulness 4-[18F]-ADAM (a transporter imaging agent) coupled with micro-PET for transporters (SERTs). A PD induced by unilateral injection 6-hydroxydopamine (6-OHDA) into right medial forebrain bundle nigrostriatal pathway, cell performed via intrastriatal brain dissected from embryonic (E14) rats. The...
Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in substantia nigra pars compacta, which leads to motor control deficits. Recently, cell transplantation a cutting-edge technique for therapy PD. Nevertheless, one key bottleneck realizing such potential allogenic immune reaction tissue grafts recipients. Cerebral dopamine neurotrophic factor (CDNF) was shown possess immune-modulatory properties that benefit neurodegenerative diseases. We hypothesized...
Patients with pathological stage IA non-small cell lung cancer (NSCLC) may relapse despite complete surgical resection without lymphovascular invasion. A method of selecting a high-risk group for adjuvant therapy is necessary. The aim this study was to assess the predictive value 18F-fluorodeoxyglucose (FDG) uptake and morphologic features computed tomography (CT) recurrence in NSCLC. One hundred forty-five patients NSCLC who underwent pretreatment FDG positron emission CT evaluations were...
Parkinson's disease (PD) is a neurodegenerative characterized by loss of dopaminergic neurons in the nigrostriatal pathway. Apart from effective strategies to halt underlying neuronal degeneration, cell replacement now offers novel prospects for PD therapy. Porcine embryonic neural tissue has been considered an alternative source human fetal grafts disorders because its use avoids major practical and ethical issues. This study was undertaken evaluate effects day 27 (E27) porcine...
Introduction: The biokinetics of radioiodine (RAI) in thyroid cancer patients are complex. This study aims to develop a practical approach for assessing RAI predict patient discharge time and estimate radiation exposure caregivers. Methods: We retrospectively reviewed data from with differentiated carcinoma undergoing treatment. Serial dose rates were dynamically collected during hospitalization fitted biexponential model assess the biokinetic features: uptake fraction tissue (Ft) effective...
The pathology of Parkinson's disease (PD) results mainly from nigrostriatal pathway damage. Unfortunately, commonly used PD therapies do not repair the disconnected circuitry. It has been reported that using kainic acid (KA, an excitatory amino acid) in bridging transplantation may be useful to generate artificial tract and reconstruct 6-hydroxydopamine (6-OHDA) lesioned rats. In this study, we KA a co-graft rat olfactory ensheathing cells (OECs) E14 embryonic ventral mesencephalic (VM)...
Malignant struma ovarii is a rare disease in gynecology and the optimal treatment regimen for tumor remains obscure. We present patient who had malignant with peritoneal implants pelvic structures liver metastases shown on posttreatment iodine I-131 single-photon emission tomography (SPECT) low-dose computed (CT). The roles of ablation management are reviewed discussed.
Purpose The aim of this study was to evaluate the clinical role technetium-99m pertechnetate (Tc-99m) imaging in thyroidectomized differentiated thyroid cancer patients immediately before radioiodine-131 (I-131) treatment (Tx). Patient and methods Eighty-six consecutive post-total-thyroidectomy (15 men, 71 women; mean age: 46.8 years) with pathologically diagnosed were retrospectively studied. Tc-99m I-131 Tx using both patient-based lesion-based measurements analyzed further compared those...
Abstract Disaster medicine education in medical curricula is scarce and frequently nonexistent. It reasonable to initiate educational approaches for physicians this field at the school level. An understanding of disaster health care system during massive casualty incidents has been recommended as an integral part curriculum United States Germany. The goal reformed was develop a longitudinal integrated military program extending from first year sixth based on previously separated clinical...
Objectives To evaluate combined PET-computed tomography (CT) criteria for differentiating between granulomatous disease (GD) and malignancy (CA) in oncologic PET–CT studies. Methods Sixty-two patients who were referred fluoro-2-deoxyglucose (FDG) evaluation of pulmonary lesion(s) without a history concurrent infection studied. was performed 1.5 h after intravenous administration 555 MBq 18F-FDG the fasting state with oral contrast. Combined including (i) calcifications (Ca2+) within lymph...
A female patient aged 75 years presented with an incidental pulmonary nodule without FDG uptake when undergoing PET/CT. Without obtaining histologic diagnosis, the follow-up PET/CT 2 later demonstrated intense avidity within previously FDG-negative tumor. After surgery, pathologic diagnosis is lymphoepithelioma-like carcinoma (LELC). LELCs are unique because of similarities undifferentiated nasopharyngeal lymphoepithelioma and a better prognosis as compared other lung malignancies. However,...
(1) Background: The study aimed to investigate the association between radioactive iodine (RAI) treatment and long-term gastrointestinal disorders including ulcers, atrophic gastritis, secondary malignant neoplasm of stomach in patients with thyroid cancer. (2) Methods: data were extracted from National Health Insurance Database (NHIRD) Taiwan 2000 2015. Patients ages older than 20 cancer after thyroidectomy included divided into groups RAI (study cohort) without (comparison cohort)....