A5100335838- Inflammatory Bowel Disease
- Urinary Bladder and Prostate Research
- Prostate Cancer Diagnosis and Treatment
- Microscopic Colitis
- Bladder and Urothelial Cancer Treatments
- Renal cell carcinoma treatment
- Renal and related cancers
- Pelvic floor disorders treatments
- Pediatric Urology and Nephrology Studies
- Urinary Tract Infections Management
- Helicobacter pylori-related gastroenterology studies
- Kidney Stones and Urolithiasis Treatments
- Minimally Invasive Surgical Techniques
- Urologic and reproductive health conditions
- Urinary and Genital Oncology Studies
- Urological Disorders and Treatments
- Pregnancy and Medication Impact
- Hormonal and reproductive studies
- Surgical Simulation and Training
- Pancreatic and Hepatic Oncology Research
- Tracheal and airway disorders
- Prostate Cancer Treatment and Research
- Eosinophilic Esophagitis
- Gut microbiota and health
- Ureteral procedures and complications
Lanzhou University
2024-2025
Lanzhou University Second Hospital
2024-2025
North Sichuan Medical University
2024
Affiliated Hospital of North Sichuan Medical College
2017-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2011-2024
Second Affiliated Hospital of Xi'an Jiaotong University
2022
Weatherford College
2022
Southern Medical University
2022
Vanderbilt University
2021
Nanchang University
2020
As accessible diagnostic approaches fail to differentiate between ulcerative colitis (UC) and Crohn's (CC) in one-third of patients with predominantly colonic inflammatory bowel disease (IBD), leading inappropriate therapy, we aim investigate the serum cytokine levels these search molecular biometric markers delineating UC from CC. We measured 38 cytokines, chemokines, growth factors using magnetic-bead-based multiplex immunoassay 25 patients, 28 CC 30 controls. Our results are compared...
The aims of this study were to evaluate the C-reactive protein/albumin ratio (CRP/ALB), inflammatory markers, and parameters from complete blood count (CBC) in patients with bowel disease (IBD) their associations activity.A total 876 IBD patients, composed 275 ulcerative colitis (UC) 601 Crohn's (CD), included retrospective study, serum protein (CRP), albumin (ALB), erythrocyte sedimentation rate (ESR), CBC measured. To explore activity, Mayo score Crohn activity index used assess UC CD...
The prevalence of depression is high in patients with Crohn's disease (CD). We examined the influence affective-cognitive symptoms on risk exacerbation CD.We studied 2,144 adult volunteers a self-reported diagnosis CD who completed baseline survey that included demographics, status, and an index depression. Linear logistic regression analyses were used to determine whether status at 12 months was associated measure Analyses adjusted for confounders including age, gender, race, activity,...
Inflammatory bowel disease (IBD) is a notable health problem and may considerably affect the quality of human life. Previously, protective roles tryptanthrin (TRYP) against dextran sulfate sodium (DSS) induced colitis has been proved, but concrete mechanism remained elusive. It suggested that TRYP could diminish weight loss improve conditions mice with DSS colitis. Hematoxylin eosin staining revealed histopathological structure colon tissue. Two signaling pathways (TNF-α/NF-κBp65 IL-6/STAT3)...
Background: With the rapid advancement of artificial intelligence in health care, large language models (LLMs) demonstrate increasing potential medical applications. However, their performance specialized oncology remains limited. This study evaluates multiple leading LLMs addressing clinical inquiries related to bladder cancer (BLCA) and demonstrates how strategic optimization can overcome these limitations. Methods: We developed a comprehensive set 100 questions based on established...
Incidence and prevalence rates trends of inflammatory bowel disease (IBD) in China remain largely unknown.This study aimed to estimate the nationwide incidence IBD identify its noticeable between 2013 2016.We conducted a population-based analysis using data from National Urban Employee Basic Medical Insurance database. Patients with at least three claims diagnosis were identified. A Joinpoint regression model was used analyze annual percent change (APC) age-standardized prevalence.The...
Background: Clinical data on the correlation of dyslipidaemia with long-term outcomes ulcerative colitis (UC) are limited. This study aimed to evaluate impact lipid levels disease activity and prognosis in UC. Methods: The retrospective UC patients who had detailed profiles were collected from January 2003 September 2020. All followed-up 30 2021. UC-related surgery tumorigenesis. Results: In total, 497 included analysis. Compared normal levels, those commonly presented more serious activity....
Objective: To investigate the effect of Astragaloside IV (AS-IV) on regulation Wnt/β-catenin signaling pathway in rats with unilateral ureteral obstruction (UUO). Methods: Rat renal interstitial fibrosis models were prepared using ligation. Rats randomly divided into sham group, group AS-IV (33mg/kg), and receiving varied doses (3.3, 10, 33 mg/kg). Immunohistochemical analysis, real-time fluorescence quantitative PCR (FQ-PCR), western blot used to detect expression genes proteins associated...
Common treatments for benign prostatic hyperplasia include 5α-reductase inhibitors and α-adrenergic receptor antagonists. However, these can only partially decrease the risk of progression. SRD5A1 SRD5A2 are inhibitor targets. We investigated association between drug efficacy single nucleotide polymorphisms in genes a Chinese population.We genotyped 11 tagging total 426 cases 1,008 controls from Xinhua Hospital, Shanghai, People's Republic China. Cases were treated with type II tested...
Evidence link bacterial enterotoxins to apparent crypt-cell like cells (CCLCs), and Alpha Defensin 5 ( DEFA5 ) expansion in the colonic mucosa of Crohn’s colitis disease (CC) patients. These areas ectopic ileal metaplasia, positive for Paneth cell (PC) markers are consistent with diagnosis CC. Retrospectively, we: 1. Identified 21 patients indeterminate (IC) between 2000–2007 were reevaluation their final clinical 2014 after a followed-up mean 8.7±3.7 (range, 4–14) years. Their initial...
Abstract Background The rising prevalence of opportunistic infections (OIs) in inflammatory bowel disease (IBD) conjunction with the use biologics/immunosuppressive agents has garnered attention. However, there is a dearth research on OIs Mainland China. This study seeks to evaluate national ratio trend IBD and elucidate influence economic climate factors patients their outcomes. Methods nationwide data was obtained from Inpatient medical record home page via Health Statistics Information...
The prevalence of Obstructive Sleep Apnea (OSA) is high, and there are many complications. Few studies have reported the relationship between OSA kidney stones. purpose this study to explore whether people at risk will increase