A5102802140- Saffron Plant Research Studies
- Microbial Natural Products and Biosynthesis
- Plant-Microbe Interactions and Immunity
- Enzyme Structure and Function
- Iron Metabolism and Disorders
- Phytochemical compounds biological activities
- Medicinal Plants and Bioactive Compounds
- Peptidase Inhibition and Analysis
- Marine Sponges and Natural Products
- Ubiquitin and proteasome pathways
- Tumors and Oncological Cases
- Cell Adhesion Molecules Research
- Machine Learning in Bioinformatics
- Neuroblastoma Research and Treatments
- Chromatin Remodeling and Cancer
- Mitochondrial Function and Pathology
- Tea Polyphenols and Effects
- TGF-β signaling in diseases
- Nausea and vomiting management
- Soft tissue tumors and treatment
- interferon and immune responses
- Garlic and Onion Studies
- Lung Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Vascular Tumors and Angiosarcomas
The University of Tokyo
2021-2025
Chenzhou First People's Hospital
2025
Zhejiang University of Technology
2019-2024
Southern University of Science and Technology
2023-2024
Shenzhen Third People’s Hospital
2023
Shanghai Pulmonary Hospital
2023
Tongji University
2023
Nanjing University of Science and Technology
2023
Tsinghua University
2023
Qilu Hospital of Shandong University
2017-2022
Acute hepatitis E (AHE) poses a significant threat to global public health, particularly among women of childbearing age (WCBA), who are at heightened risk for severe pregnancy-related complications. This study aimed delineate the temporal trends and project future incidence AHE in WCBA, providing insights crucial targeted prevention control strategies.
OPINION article Front. Bioeng. Biotechnol., 02 March 2023Sec. Bioprocess Engineering Volume 11 - 2023 | https://doi.org/10.3389/fbioe.2023.1127166
Purpose Recommendations from the N ational H ealth C ommission of hina (NHCC) and I nternational K i67 W orking G roup (IKWG) were issued to guide immunohistochemistry (IHC)-based Ki67 scoring for breast cancer patients in daily clinical practice. They evaluated this multi-institutional study alongside results Quantitative Dot Blot (QDB) method. Methods Three alternative adjacent sections 40 primary ER+ resection blocks randomly assigned a number 1 120 staining reviewed by 21 pathologists,...
Microbial corrosion poses a significant threat to architectural heritage worldwide. This study used metagenomics investigate microbial diversity and taxonomic groups present in the door walls of Ji family’s residential houses, as well their biological functions chemical cycles. Taxonomic annotation revealed predominant taxa associated with wall corrosion, shedding light on potential impact structural integrity. Moreover, analyzing metabolites pathways these communities allows for thorough...
Constipation is a common gastrointestinal disorder characterized by changes in intestinal habits. Increasing evidence indicates that long-term use of irritant laxatives causes serious side effects. Meanwhile, more than 50% patients are dissatisfied with sense non-prescriptional laxatives. β-glucans natural polysaccharides widely found yeast, fungus, and plants, which have been reported to exhibit various pharmacological The aim this study was characterize the effect extracted from bread...
Primary liver cancer is one of the most common and aggressive human malignancies worldwide. As numerous studies have revealed that WW domain containing E3 Ub‑protein ligase 2 (WWP2) exerts cancer‑specific functions, present study assessed role WWP2 in cancer. was to be significantly overexpressed tissues compared with paired normal at mRNA as well protein level. Furthermore, small interfering RNA-mediated knockdown cell lines demonstrated inhibit proliferation, cause cycle arrested G1 phase...
Abstract Multicellular resistance (MCR) is produced because multicellular spheroids (MCSs) are formed with a broad cell–cell connection when cultured in three‐dimensions, which limits the clinical treatment efficacy solid tumors. Focal adhesion kinase (FAK) plays an important role apoptosis, survival and cell between cells their extracellular matrix. In this study, we investigated expressions of FAK, Akt NF‐κB human colorectal cancer (CRC), effects FAK gene silencing on MCSs formation...
Four new curvularin-type macrolides were isolated from a marine fungus <italic>Penicillium Sumatrense</italic> and their absolute configurations determined by CD spectra modified Mosher's methods.
The effects of a proprietary topical formulation containing EGCG-stearate in 100% glycerin USP were studied two volunteer patients with recurrent herpes simplex (HSV) type 1. Application during early onset (prodromal stage) patient labialis prevented lesion progression. In second herpetic stomatitis, application the formula later stage (inflammation led to remarkably shortened duration symptoms. contrast, third provided only as placebo failed demonstrate any therapeutic or preventive effect...
The role and clinical implication of the WWP2 E3 ubiquitin ligase in liver cancer are poorly understood. In current study, we investigated expression level its functions cell adhesion, invasion, migration cancer. We used real-time PCR to detect adjacent samples from People's Hospital Lishui also analyzed Cancer Genome Atlas (TCGA) RNA-seq data by bioinformatics. Migration invasion were detected transwell analysis. a strong tumor tissues Lishui, survival rate was significantly higher patients...
<b><i>Background and Aim:</i></b> So far, the understanding of role Epstein-Barr virus-induced gene 3 (<i>EBI3</i>) in breast cancer has been limited. This study uncovers functional clinical significance <i>EBI3</i> patients. <b><i>Patients Methods:</i></b> The expression levels <i>EBI3</i>, <i>IL-27p28</i>, <i>IL-12p35</i> were measured by quantitative real-time reverse transcription...
The morphological changes from single-cell yeast to filamentous hypha form are critical in plant pathogenic smut fungi. This dimorphic switch is tightly regulated by complex gene pathways development. phytopathogenic basidiomycetes Sporisorium scitamineum displays a transition budding growth of haploid cells the dikaryon, which enables fungi forage for nutrients and evade host immune system. In search compounds that affect instead killing cell directly, natural product, mycophenolic acid...
Three new antibacterial spirooxindole alkaloids, spirobrefeldins A-C (1-3), together with four known analogs, spirotryprostatin M (4), G (5), 12β-hydroxyverruculogen TR-2 (6), and 12α-hydroxyverruculogen (7), were isolated from terrestrial fungus Penicillium brefeldianum. All the compounds elucidated extensively by interpretation of their NMR (1D 2D) spectra high-resolution mass data, absolute configurations determined computational chemistry CD spectra. The spiro carbon C-2 in (5) C...