A5085740504- Inflammasome and immune disorders
- MicroRNA in disease regulation
- Surgical Simulation and Training
- Galectins and Cancer Biology
- Surgical Sutures and Adhesives
- Innovations in Medical Education
- Cardiomyopathy and Myosin Studies
- Cancer-related molecular mechanisms research
- Anatomy and Medical Technology
- Circular RNAs in diseases
- Epigenetics and DNA Methylation
- RNA and protein synthesis mechanisms
- Wnt/β-catenin signaling in development and cancer
- Heme Oxygenase-1 and Carbon Monoxide
- Facial Rejuvenation and Surgery Techniques
- Hydrogen's biological and therapeutic effects
- RNA modifications and cancer
- Dermatologic Treatments and Research
- Medicinal Plants and Bioactive Compounds
- Minimally Invasive Surgical Techniques
- Congenital heart defects research
- Empathy and Medical Education
Hebei University of Engineering
2025
Affiliated Hospital of Hebei University
2025
Shanghai Jiao Tong University
2020-2023
Shanghai First People's Hospital
2020-2023
Children's Hospital of Fudan University
2020-2022
Pyroptosis belongs to a novel inflammatory programmed cell death pathway, with the possible prognosis of endometrial cancer related terminal protein GSDMD. Hydrogen exerts biphasic effect on by promoting tumor and protecting normal cells, which might initiate GSDMD pathway-mediated pyroptosis.We performed immunohistochemical staining western immunoblotting analysis observe expression NLRP3, caspase-1, in human xenograft mice tissue lines. We investigated treatment hydrogen could boost ROS...
Abstract Maternal hyperglycemia potentially inhibits the development of fetal heart by suppressing cardiomyocyte proliferation and promoting apoptosis. Different studies have indicated that miRNAs are key regulators proliferation, differentiation, apoptosis play a protective role in variety cardiovascular diseases. However, biological function miRNA-23a hyperglycemia-related injury is not fully understood. The present study investigated effect miRNA-23a-3p on cell myocardial model induced...
As a member of the miR-29 family, miR-29b regulates global DNA methylation through target methyltransferases (DNMTs) and acts as both key effector in methylation. In this study, we found that miR-29b-3p expression was inversely correlated with DNMT heart tissues patients congenital disease (CHD), but whether it interacts DNMTs cardiomyocytes remains unknown. Further results revealed feedback loop between cardiomyocytes. Moreover, inhibitor relieved deformity hypomethylated zebrafish restored...
In advanced and recurrent endometrial carcinoma (EC), the current state of immuno- or targeted therapy remains in clinical research phase. Our study aimed to explore role ESCRT machinery maintaining cell membrane integrity reversing pyroptotic death.Immunohistochemistry, western blotting, co-immunoprecipitation were performed determine expression relationship between GSDMD, CHMP4B, VPS4A. We employed techniques such as FITC Annexin V/propidium iodide staining, Ca2+ fluorescence intensity,...
Objectives . The standardized residency training (SRT) program in China is an important link for continuing education and clinical work graduate students. purpose of our study was to enable educators maintain the effectiveness hysteroscopy teaching techniques make students well experienced surgery, thus demonstrating that higher efficiency can lead better proficiency surgery. Methods We generated resident-as-teacher round tutor guided hysteroscopic surgery as a questionnaire based on mastery...
Abstract Background Few previous studies have introduced general techniques to overcome the “chopstick effect” in laparoendoscopic single-site surgery (LESS). We aim investigate and highlight key ergonomic methodologies for gynaecologic LESS based on surgeon’s hands-on performance. Methods The first author surgeon A reviewed analyzed procedures performed by herself how she taught B from January 2021 April 2022. were classified technical difficulty learning periods, skills of module...
In advanced and recurrent endometrial carcinoma (EC), the current state of immuno- or targeted therapy remains in clinical research phase. Our study aimed to explore role ESCRT machinery maintaining cell membrane integrity reversing pyroptotic death. Immunohistochemistry, western blotting, co-immunoprecipitation were performed determine expression relationship between GSDMD, CHMP4B, VPS4A. We employed techniques such as FITC Annexin V/propidium iodide staining, Ca2+ fluorescence intensity,...
Abstract Background: Extreme competition for grant funding or publications to gain career promotion in affiliated hospital has outsized negative effects on doctor China these years. This research seeks explore the relationships between evaluation of teaching physician and their actual aptitude towards promotion.Methods: study was offered all teachers medical students at Shanghai General Hospital Jiao Tong University. A web-based survey conducted identify individuals’ physician. total 140...