A5101023772- Plant Molecular Biology Research
- Genomics and Phylogenetic Studies
- Bioinformatics and Genomic Networks
- Cancer-related molecular mechanisms research
- Chromosomal and Genetic Variations
- Animal Disease Management and Epidemiology
- Computational Drug Discovery Methods
- RNA and protein synthesis mechanisms
- Genetic and phenotypic traits in livestock
- Viral gastroenteritis research and epidemiology
- RNA modifications and cancer
- Influenza Virus Research Studies
- Gene Regulatory Network Analysis
- Generative Adversarial Networks and Image Synthesis
- Oral microbiology and periodontitis research
- Genomic variations and chromosomal abnormalities
- Advanced Neural Network Applications
- Food Supply Chain Traceability
- Biochemical and Structural Characterization
- Advanced Graph Neural Networks
- Plant nutrient uptake and metabolism
- Animal Behavior and Welfare Studies
- Genomics and Chromatin Dynamics
- Legume Nitrogen Fixing Symbiosis
- Cell Image Analysis Techniques
Northwest A&F University
2017-2025
Guangdong Ocean University
2023-2025
Chengdu University of Information Technology
2024
China National Petroleum Corporation (China)
2022
Wenzhou Medical University
2022
Guangxi Normal University
2019
Agriculture and Forestry University
2019
University of Nebraska–Lincoln
2015
China Medical University
2015
Summary Apple ( Malus × domestica ) trees are vulnerable to freezing temperatures. However, there has been only limited success in developing cold‐hardy cultivars. This lack of progress is due at least partly understanding the molecular mechanisms tolerance apple. In this study, we evaluated potential roles for two R2R3 MYB transcription factors TF s), 88 and paralogous FLP 124), cold stress apple Arabidopsis . We found that 124 positively regulate cold‐responsive gene expression both...
The Universal Soil Loss Equation (USLE) and its revised version (RUSLE) are often used to estimate soil erosion at regional landscape scales. USLE/RUSLE contain parameters for slope length factor (L) steepness (S), usually combined as LS. However a major limitation is the difficulty in extracting LS factor. Methods based on geographic information systems have been developed last two decades. L can be calculated large watersheds using unit contributing area (UCA) or (λ) input parameters. Due...
Abstract Plant phenotypes respond to environmental change, an adaptive capacity that is at least partly transgenerational. However, epigenetic components of this interplay are difficult measure. Depletion the nuclear-encoded protein MSH1 causes dramatic and heritable changes in plant development, here we show crossing these altered plants with isogenic wild type produces epi-lines heritable, enhanced growth vigour. Pericentromeric DNA hypermethylation occurs a subset msh1 mutants, indicative...
Evidence is compelling in support of a naturally occurring epigenetic influence on phenotype expression land plants, although discerning the contribution difficult. Agriculturally important attributes like heterosis, inbreeding depression, phenotypic plasticity, and environmental stress response are thought to have significant components, but unequivocal demonstration this often infeasible. Here, we investigate gene silencing single nuclear gene, MutS HOMOLOG1 (MSH1), tomato (Solanum...
The emergence of epitranscriptome opened a new chapter in gene regulation. 5-methylcytosine (m5C), as an important post-transcriptional modification, has been identified to be involved variety biological processes such subcellular localization and translational fidelity. Though high-throughput experimental technologies have developed applied profile m5C modifications under certain conditions, transcriptome-wide studies are still hindered by the dynamic reversible nature lack computational...
H4Nx avian influenza viruses (AIVs) have been isolated from wild birds and poultry can also cross the species barrier to infect mammals (pigs muskrats). The widespread presence of these in their ability be transmitted interspecies make them an undeniable hazard farming industry. In present study, we collected fecal swab samples Guangdong Province January 2019 March 2024, various subtypes AIVs were isolated, including 19 strains H4 subtype AIVs. Further analysis was conducted on internal...
Interaction between proteins often depends on the sequence features and structure of proteins. Both these are helpful for machine learning methods to predict (protein-protein interaction) PPI sites. In this study, we introduced a new feature: concave-convex feature protein surface, which was computed by structural data in Protein Data Bank database. And then, prediction model combining constructed, named SSPPI_Ensemble (Sequence Structure geometric feature-based site prediction). Three...
To investigate the effect of ficin, a type proteases, on Candida albicans (C. albicans) biofilm, including forming and pre-formed biofilms.Crystal violet tests together with colony unit (CFU) counts were used to detect fungal biofilm biomass. Live/dead staining biofilms observed by confocal laser scanning microscopy was monitor activity. Finally, gene expression C. within assessed qRT-PCR.According our results, biomass dramatically reduced ficin in both formation biofilms, as revealed...
Water deficit is one of the main limiting factors for apple growth and production. Root architecture plays an important role in drought tolerance plants. However, little known about molecular basis root system trees under drought. In this study, we compared morphology two widely used rootstocks (R3 Malus sieversii) Our results suggested that M. sieversii more tolerant to than R3, since had a higher ratio shoot as well hydraulic conductivity long-term conditions. We then performed...
The H3-subtype of avian influenza virus (AIV) is one the most frequently detected low pathogenic (LPAIV) subtypes in birds and fowls, causing substantial economic loss to poultry industry. Most importantly, besides poultry, mammals could also be infected with it, such as swines, canines, equines, felines, humans, posing a serious public health threat. This allows persist widely wild for long time, where it may mix other subtypes, providing conditions viral recombination or reassortment....
Motivation: Pentatricopeptide repeat (PPR) is a triangular pentapeptide domain that plays vital role in plant growth. In this study, we seek to identify PPR coding genes and proteins using mixture of feature extraction methods. We use four single methods focusing on the sequence, physical, chemical properties as well amino acid composition, mix features. The Max-Relevant-Max-Distance (MRMD) technique applied reduce dimension. Classification uses random forest, J48, naïve Bayes with 10-fold...
A widely used approach in transcriptome analysis is the alignment of short reads to a reference genome. However, owing deficiencies specially designed analytical systems, unmapped genome sequence are usually ignored, resulting loss significant biological information and insights. To fill this gap, we present Comprehensive Assembly Functional annotation Unmapped RNA-Seq data (CAFU), Galaxy-based framework that can facilitate large-scale RNA sequencing (RNA-Seq) from single- mixed-species...
Discovering driver pathways is an essential task to understand the pathogenesis of cancer and design precise treatments for patients. Increasing evidences have been indicating that multiple often function cooperatively in carcinogenesis. In this study, we propose approach called CDPath discover cooperative pathways. first uses Integer Linear Programming explore core modules from mutation profiles by enforcing co-occurrence functional interaction relations between modules, maximizing mutual...
Alternative splicing enables a gene translating into different <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">isoforms</i> and the corresponding proteoforms, which actually accomplish various biological functions of living body. Isoform-isoform interactions (IIIs) provide higher resolution interactome to explore cellular processes disease mechanisms than canonically studied protein-protein (PPIs), are often recorded at coarse level. The...
Cell direct reprogramming technology has been rapidly developed with its low risk of tumor and avoidance ethical issues caused by stem cells, but it is still limited to specific cell types. Direct from an original target type needs the similarity regulatory network. The position function cells in vivo, can provide some hints about similarity. However, further clarification based on molecular level studies.CellSim therefore offer a solution for calculation tool bioinformatics researchers....
Avian paramyxoviruses (APMV) belong to the subfamily Avulavirinae of family Paramyxoviridae and include 22 distinct subtypes or serotypes (1-22). paramyxovirus serotype 12 (APMV-12) is found sporadically in wild birds worldwide, reports from only Italy Taiwan have been published date; information on its genetic variation biological characteristics still limited. In this study, 3 APMV-12 strains, designated WB19, LY9, LY11, were isolated 8643 bird faecal samples during annual influenza virus...
The carcinogenesis is typically involved with the cooperations of multiple pathways. Therefore, discovering cooperative driver pathways can provide more precise therapy to patients. Existing pathway identification methods only identify few (or previously well-known) pathways, because noisy or single type knowledge, insufficient attention cooperations. To address these problems, we develop a novel approach called CoPath that leverages genomic alteration profiles and bi-clustering discover...
In the indoor application environment, in order to improve overall efficiency of service robot target detection, combined with deep learning detection theory, SSD algorithm and a lightweight neural network mobilenetv2 are design new algorithm, which improves certain extent. The main improvements this paper as follows. Firstly, using for reference, multi-scale feature extraction is carried out image, different sizes targets detected at scales; Secondly, process matching actual region...
Nano-blocking technology has become a key to overcoming prominent bottleneck in shale gas development. In this paper, poly(ST-VS-B-E) was synthesized by Michael addition reaction using styrene, vinyl sodium sulfonate, ethyl methacrylate, and butyl acrylate. Poly(ST-VS-B-E) characterized infrared spectroscopy analysis, laser scattering thermogravimetric analysis. The rheological properties of drilling fluid with were studied testing the fluid’s properties. results showed that median particle...