A5101742499- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Platelet Disorders and Treatments
- Autoimmune Bullous Skin Diseases
- Cardiac Imaging and Diagnostics
- Lymphoma Diagnosis and Treatment
- Monoclonal and Polyclonal Antibodies Research
- Chronic Lymphocytic Leukemia Research
- Systemic Lupus Erythematosus Research
- Medical Imaging Techniques and Applications
- Immunodeficiency and Autoimmune Disorders
- Dysphagia Assessment and Management
- Pregnancy and Medication Impact
- Cardiac Arrhythmias and Treatments
- TGF-β signaling in diseases
- Dialysis and Renal Disease Management
- Blood groups and transfusion
- Advanced MRI Techniques and Applications
- Glaucoma and retinal disorders
- Ion Transport and Channel Regulation
- Acute Kidney Injury Research
- Heart Failure Treatment and Management
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Amyloidosis: Diagnosis, Treatment, Outcomes
International University of Health and Welfare
2020-2021
Zenyaku Kogyo (Japan)
2021
Otsuka (Japan)
2021
Tsukuba Memorial Hospital
2019
Japan Clinical Cancer Research Organization
2012-2017
Kumamoto University
2012
Lund University
2009-2010
Kitasato University
2009
Rakuno Gakuen University
2009
Saga University
2007
Abstract Although vaccination may precipitate relapses of nephrotic syndrome (NS) in children with idiopathic NS, no data are available regarding NS activity influenza (flu) virus infections and after receiving inactivated flu vaccines. We conducted a nationwide study aged 6 months to 15 years assess the relationship between relapse, vaccination, infections. used multivariate Poisson regression model (MPRM) calculate risk ratio (RR) for infection relapse without vaccination. Data 306 were...
Background. We previously established a treatment protocol for conventional cyclosporine (Sandimmune, Novartis, Basel, Switzerland) in children with frequently relapsing nephrotic syndrome; ∼50% of patients remained relapse free 2 years, without serious adverse events. Recently, microemulsified (Neoral, Novartis), which has more stable absorption profile than cyclosporine, been developed. tested the hypothesis that is at least as effective cyclosporine. Methods. To evaluate safety and...
Although the safety and efficacy of cyclosporine in children with frequently relapsing nephrotic syndrome (FRNS) have been confirmed, no prospective follow-up data on relapse after appeared. This study is a trial 2-year treatment to investigate dependency its discontinuation.Participants who had undergone protocol microemulsified for FRNS between January 2000 December 2005 were followed an additional 2 years. The primary end point was relapse-free survival complete discontinuation...
Abstract Background Information on the epidemiology of idiopathic nephrotic syndrome (INS) in children, complications INS and side effects steroid therapy is scarce. Methods The Japanese Pediatric Survey Holding Nephrotic Syndrome, a nationwide cohort study, was conducted by Study Group Renal Disease Children enrolled 2099 children with newly diagnosed between 1 January 2010 31 December 2012. We follow-up study during first onset patients’ prognosis this cohort. Results obtained data 999...
The effect of dietary protein restriction on the progress renal dysfunction was investigated in rats with adriamycin (ADR)-induced progressive glomerular disease. Dietary reduced from 20% (normal diet) to 5% (low protein) immediately after (ADR-0w), 8 weeks (ADR-8w) or 16 (ADR-16w) repeated injection ADR. In unrestricted (ADR-UR) group were fed throughout 24-week experiment. Massive urinary developed ADR and significantly decreased by reducing all groups (ADR-0w, ADR-8w, ADR-16w). However,...
Rituximab is conditionally approved in Japan for use patients with refractory nephrotic syndrome. To meet the conditions of approval, an all-case post-marketing surveillance study was conducted to confirm real-world safety and efficacy rituximab all ages syndrome.All scheduled receive treatment syndrome were eligible register (registration: August 29, 2014 through April 15, 2016); planned observation period 2 years from initiation (intravenous infusion, 375 mg/m2 once weekly four doses). The...
14日齢から25日齢まで喘鳴症にて抗生物質と副腎皮質ホルモン剤により治療された31日齢の黒毛和種の雌子牛が､再発により北里大学獣医学部付属動物病院に入院した｡入院時､吸気時の喘鳴音､努力性呼吸､食欲不振および運動不耐性がみられた｡内視鏡検査により咽喉頭粘膜の充血､左右被裂軟骨の麻痺および右側被裂軟骨の腫脹と内側への変位が認められ､咽喉頭炎と診断した｡治療に用いた抗生物質と1日投与量(投与病日：d) は､セファゾリン1g (1-2d)､エンロフロキサシン200mg (3-22d)､リンコマイシン400mg (3-27d)､タイロシン800mg (32-44d)､オキシテトラサイクリン400mg (46-54d)であった｡抗炎症剤としてプレドニゾロン20mg(1-5d), 10mg(6-11d), 5mg(12-15d)の筋肉注射､フルニキシン140mg (16-22d)の静脈内投与を実施し､カナマイシン250mgまたはゲンタマイシン50mgと気管支拡張剤の噴霧吸入(1-10d､14-22d)およびポビドンヨードの咽喉頭部塗布(32-54d)...
Katafuchi R, Masutani K, Mizumasa T, Fujita E, Tanaka H, Ikeda Yanase Ando Fujimi S. A case of persistent acute allograft glomerulopathy with longstanding stable renal function. Clin Transplantation 2001: 15 (Supplement 5): 2–10. ©Munksgaard, 2001 Acute (AAG) characterized by hypercellularity, enlargement endothelial cells, infiltration glomeruli mononuclear cells and webs PAS‐positive material has been reported as an unusual but distinct form rejection in kidney transplant recipients. We...
Objectives: To clarify a cumulative risk of hypertension (HT), type 2 diabetes (DM), and chronic kidney disease (CKD) for all-cause cardiovascular (CV) mortality in general population. Design Methods: The study population was 74,924 apparently healthy Japanese persons (40 to 89 years old). During 405,999 person-years follow up period (median 5.59 years), 2,440 deaths including 592 CV related were observed. Cumulative impact HT, DM, CKD on estimated by Poisson regression analysis adjusted...
Abstract Although vaccination may precipitate relapses of nephrotic syndrome (NS) in children with idiopathic NS, no data are available regarding NS activity influenza (flu) virus infections and after receiving inactivated flu vaccines. We conducted a nationwide study aged 6 months to 15 years assess the relationship between relapse, vaccination, infections. used multivariate Poisson regression model (MPRM) calculate risk ratio (RR) for infection relapse without vaccination. Data 306 were...