Simon D’Alfonso

ORCID: 0000-0001-7407-8730
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About
Contact & Profiles
Research Areas
  • Digital Mental Health Interventions
  • Mental Health Research Topics
  • Impact of Technology on Adolescents
  • Child and Adolescent Psychosocial and Emotional Development
  • Schizophrenia research and treatment
  • Mental Health Treatment and Access
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Mental Health and Patient Involvement
  • Suicide and Self-Harm Studies
  • Child Development and Digital Technology
  • Semantic Web and Ontologies
  • Peer-to-Peer Network Technologies
  • Mental Health via Writing
  • Mobile Health and mHealth Applications
  • Innovative Human-Technology Interaction
  • Personality Disorders and Psychopathology
  • Telemedicine and Telehealth Implementation
  • Web Data Mining and Analysis
  • Information Retrieval and Search Behavior
  • Emotion and Mood Recognition
  • Autism Spectrum Disorder Research
  • Sociology and Cultural Identity Studies
  • Logic, Reasoning, and Knowledge
  • Crime, Deviance, and Social Control
  • Literature Analysis and Criticism

The University of Melbourne
2015-2025

Orygen
2019-2023

Orygen Youth Health
2016-2023

This paper presents a critical review of key ethical issues raised by the emergence mental health chatbots. Chatbots use varying degrees artificial intelligence and are increasingly deployed in many different domains including health. The technology may sometimes be beneficial, such as when it promotes access to information services. Yet, chatbots raise variety concerns that often magnified people experiencing ill-health. These challenges need appreciated addressed throughout pipeline. After...

10.1177/20552076231183542 article EN cc-by-nc-nd Digital Health 2023-01-01
Cassandra Wannan Barnaby Nelson Jean Addington Kelly Allott Alan Anticevic and 95 more Celso Arango Justin T. Baker Carrie E. Bearden Tashrif Billah Sylvain Bouix Matthew R. Broome Kate Buccilli Kristin S. Cadenhead Monica E. Calkins Tyrone D. Cannon Guillermo Cecci Eric Chen Kang Ik K. Cho Jimmy Choi Scott Clark Michael Coleman Philippe Conus Cheryl M. Corcoran Barbara A. Cornblatt Covadonga M. Díaz‐Caneja Dominic Dwyer Bjørn H. Ebdrup Lauren M. Ellman Paolo Fusar‐Poli Liliana Galindo Pablo A. Gaspar Carla Gerber Louise Birkedal Glenthøj Robert J. Glynn Michael P. Harms Leslie E. Horton René S. Kahn Joseph Kambeitz Lana Kambeitz‐Ilankovic John M. Kane Tina Kapur Matcheri S. Keshavan Sung‐Wan Kim Nikolaos Koutsouleris Marek Kubicki Jun Soo Kwon Kerstin Langbein Kathryn E. Lewandowski Gregory A. Light Daniel Mamah Patricia Marcy Daniel H. Mathalon Patrick D. McGorry Vijay A. Mittal Merete Nordentoft Ángela Núñez Ofer Pasternak Godfrey D. Pearlson Jesús Pérez Diana O. Perkins Albert R. Powers David R. Roalf Fred W. Sabb Jason Schiffman Jai Shah Stefan Smesny Jessica Spark William S. Stone Gregory P. Strauss Zailyn Tamayo John Torous Rachel Upthegrove Mark Vangel Swapna Verma Jijun Wang Inge Winter-van Rossum Daniel H. Wolf Phillip Wolff Stephen J. Wood Alison R. Yung Carla Agurto Mario Álvarez‐Jiménez G. Paul Amminger Marco Armando Ameneh Asgari-Targhi John D. Cahill Ricardo E. Carrión Eduardo Castro Suheyla Cetin‐Karayumak M. Mallar Chakravarty Youngsun Cho David Cotter Simon D’Alfonso Michaela Ennis Shreyas Fadnavis Clara Fonteneau Caroline X. Gao Tina Gupta Raquel E. Gur Ruben C. Gur

Abstract This article describes the rationale, aims, and methodology of Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ). is largest international collaboration to date that will develop algorithms predict trajectories outcomes individuals at clinical high risk (CHR) for psychosis advance development use novel pharmacological interventions CHR individuals. We present a description participating research networks data processing analysis coordination center, their processes...

10.1093/schbul/sbae011 article EN cc-by Schizophrenia Bulletin 2024-03-07

Introduction: Benefits from mental health early interventions may not be sustained over time, and longer-term intervention programs required to maintain clinical gains. However, due the high intensity of face-to-face treatments, this feasible. Adjunctive internet-based specifically designed for youth provide a cost-effective engaging alternative prevent loss benefits. until now online have relied on human moderators deliver therapeutic content. More sophisticated models responsive user data...

10.3389/fpsyg.2017.00796 article EN cc-by Frontiers in Psychology 2017-06-02

Implementation of targeted e-mental health interventions offers a promising solution to reducing the burden disease associated with youth depression. A single-group pilot study was conducted evaluate acceptability, feasibility, usability and safety novel, moderated online social therapy intervention (entitled Rebound) for depression relapse prevention in young people.Participants were 42 people (15-25 years) (50% men; mean age = 18.5 partial or full remission. Participants had access Rebound...

10.1111/eip.12354 article EN Early Intervention in Psychiatry 2016-06-17

This study aimed to determine whether, following two years of specialized support for first‐episode psychosis, the addition a new digital intervention (Horyzons) treatment as usual (TAU) 18 months was more effective than TAU alone. We conducted single‐blind randomized controlled trial. Participants were people with psychosis (N=170), aged 16‐27 years, in clinical remission and nearing discharge from service. They randomly assigned (1:1) receive Horyzons plus (N=86) or alone (N=84) between...

10.1002/wps.20858 article EN World Psychiatry 2021-05-18

Background Mental ill-health is the leading cause of disability worldwide. Moreover, 75% mental health conditions emerge between ages 12 and 25 years. Unfortunately, due to lack resources limited engagement with services, a majority young people affected by do not access evidence-based support. To address this gap, our team has developed multimodal, scalable digital service (Enhanced Moderated Online Social Therapy [MOST+]) merging real-time, clinician-delivered web chat counseling;...

10.2196/17155 article EN cc-by Journal of Medical Internet Research 2020-06-13

Introduction Specialised early intervention services have demonstrated improved outcomes in first-episode psychosis (FEP); however, clinical gains may not be sustained after patients are transferred to regular care. Moreover, many with FEP remain socially isolated poor functional outcomes. To address this, our multidisciplinary team has developed a moderated online social media therapy (HORYZONS) designed enhance functioning and maintain from specialist services. HORYZONS merges: (1)...

10.1136/bmjopen-2018-024104 article EN cc-by-nc BMJ Open 2019-02-01

The therapeutic alliance (TA), the relationship that develops between a therapist and client/patient, is critical factor in outcome of psychological therapy. As mental health care increasingly adopting digital technologies offering interventions may not involve human therapists, notion TA requires exploration. To date, there has been some incipient work on developing measures to assess conceptualization for apps. However, few have proposed more or less derivatives from psychology used...

10.2196/21895 article EN cc-by JMIR Mental Health 2020-12-29

The primary objective was to determine the acceptability, feasibility and safety of a novel digital intervention (Entourage) for young people with prominent social anxiety symptoms, particular focus on engagement men. secondary aim explore whether associated clinically significant improvements clinical variables known co-occur anxiety.A multidisciplinary team comprising mental health clinicians, researchers, adult fiction writers, comic artist lived experience developed Entourage platform in...

10.1016/j.invent.2020.100323 article EN cc-by-nc-nd Internet Interventions 2020-04-01

Online social networking interventions have potential to support young people who experience suicidal thoughts by specifically addressing interpersonal risk factors for suicide, but may also pose a of harm. This uncontrolled, single-group pilot study aimed evaluate the safety, feasibility, and acceptability an enhanced online intervention (“Affinity”) among sample experienced active ideation, explore changes in clinical outcomes therapeutic targets intervention. Twenty with current or recent...

10.3390/ijerph17072435 article EN International Journal of Environmental Research and Public Health 2020-04-03

Digital interventions have potential applications in promoting long-term recovery and improving outcomes first-episode psychosis (FEP). This study aimed to evaluate the cost-effectiveness of Horyzons, a novel online social therapy support young people aged 16-27 years following discharge from FEP services, compared with treatment as usual (TAU) healthcare sector societal perspective.

10.1093/schbul/sbad071 article EN cc-by-nc-nd Schizophrenia Bulletin 2023-05-24

In this article, we show how a technology-mediated mental health therapy involving psycho-education, therapist moderators, and social networking can provide support for carers of young people with illness. This multi-faceted tool provides opportunities users to adapt the system their needs, leading us refocus goal treatment adherence toward relatively new phenomenon in HCI, concordance, which has not previously been examined HCI literature relation online mental-health tools. Concordance...

10.1145/3301421 article EN ACM Transactions on Computer-Human Interaction 2019-02-21

Context sensing on smartphones is often used to understand user behaviour. Amongst the many available sensors, collection of text crucial due its richness. However, previous work has been limited collecting only from keyboard input, or intermittently screen indirectly by taking screenshots and applying optical character recognition. Here, we present a novel software sensor that unobtrusively continuously captures all smartphones. We conducted validation study with 21 participants over...

10.1145/3613904.3642347 article EN cc-by 2024-05-11

Background Integrating innovative digital mental health interventions within specialist services is a promising strategy to address the shortcomings of both face-to-face and web-based services. However, despite young people’s preferences calls for integration these services, current rarely offer blended models care. Objective This pilot study tested an integrated transdiagnostic intervention (eOrygen) as model care youth psychosis borderline personality disorder. The primary aim was evaluate...

10.2196/49217 article EN cc-by JMIR Mental Health 2024-01-12

<sec> <title>BACKGROUND</title> While meditation applications (apps) are increasingly popular, there is limited understanding of how much people engage with them outside clinical trials. Accordingly, the ways in which general population uses apps and factors that influence their usage remain relatively unclear. </sec> <title>OBJECTIVE</title> Our aim to explore amount app use predict engagement. <title>METHODS</title> We conducted a cross-sectional survey recent users, including...

10.2196/preprints.71960 preprint EN cc-by 2025-01-30

ABSTRACT Purpose Physical activity could be associated with psychological symptoms in young people major depressive disorder (MDD). Using actigraphy and ecological momentary assessment (EMA), we investigated the associations between physical stress, anxiety positive negative affect MDD. Methods Actigraphy EMA were collected daily 40 participants (aged 16–25 years) MDD over 8 weeks. Multi‐level linear mixed models used to examine within‐ between‐person of depression affect. Results...

10.1111/eip.70018 article EN cc-by Early Intervention in Psychiatry 2025-02-23

Abstract Aim We evaluated the feasibility and acceptability of Horyzons, an online social media platform designed to facilitate relationship development among, introduce therapeutic content to, first‐episode psychosis (FEP) clients. also whether participation in was related reduced loneliness, improved integration increased psychological well‐being. Methods Twenty‐six participants diagnosed with a schizophrenia spectrum disorder were provided access moderated Horyzons for 12 weeks. During...

10.1111/eip.12947 article EN Early Intervention in Psychiatry 2020-02-17

This qualitative study explores mental health clinician perspectives on how information extracted from client interactions with digital devices such as smartphones and the Internet (their footprint data) can inform treatment. The process of learning about an individual's behaviours psychology their footprint, what has been termed 'digital phenotyping', emerged in recent years a field research potential to offer insights clinical value that could be used predict/detect ill-health agenda...

10.1016/j.actpsy.2023.103886 article EN cc-by-nc-nd Acta Psychologica 2023-03-14

Fully automated mental health apps provide a promising opportunity for increasing access to care and resources. Given this opportunity, continued research into the utility effectiveness of is crucial. Therapeutic alliance (TA) refers relationship between client healthcare professional, has been shown be an important predictor clinical outcomes in face-to-face therapy. significance TA traditional therapy, it explore whether notion digital therapeutic (DTA) context fully also plays role...

10.1002/cpp.2851 article EN cc-by-nc-nd Clinical Psychology & Psychotherapy 2023-04-11
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