- Parasitic Infections and Diagnostics
- Toxoplasma gondii Research Studies
- Herpesvirus Infections and Treatments
- Amoebic Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Coccidia and coccidiosis research
- Bacteriophages and microbial interactions
- Viral Infections and Vectors
- Cytomegalovirus and herpesvirus research
- Pneumocystis jirovecii pneumonia detection and treatment
- Animal Disease Management and Epidemiology
- Vector-Borne Animal Diseases
- T-cell and Retrovirus Studies
- Extracellular vesicles in disease
- Air Quality and Health Impacts
- Antimicrobial Peptides and Activities
- Antifungal resistance and susceptibility
- Mosquito-borne diseases and control
- Autophagy in Disease and Therapy
- Parasitic Diseases Research and Treatment
- Plant responses to water stress
- Rabies epidemiology and control
- Plant Molecular Biology Research
- Inflammasome and immune disorders
- Insect symbiosis and bacterial influences
Guizhou University
2025
Shandong Freshwater Fisheries Research Institute
2025
Peking University
2024
Peking University Cancer Hospital
2024
Sir Run Run Shaw Hospital
2024
Zhejiang University
2024
Jilin University
2008-2023
Jilin Academy of Agricultural Sciences
2013-2023
Chongqing University
2023
Shandong University
2011-2021
The management of chronic wounds in diabetes remains challenging due to the complexity impaired wound healing, delayed susceptibility infection, and elevated risk reopening, highlighting need for effective with innovative approaches such as multifunctional hydrogels. Here, we have produced HA-DA@rhCol hydrogels consisting dopamine-modified hyaluronic acid recombinant human collagen type-III (rhCol) by oxidative coupling catechol group using H
Giardia duodenalis , also known as G . intestinalis or lamblia is the major cause of giardiasis leading to diarrheal disease with 280 million people infections annually worldwide. Extracellular vesicles (EVs) have emerged a ubiquitous mechanism participating in cells communications. The aim this study explore roles EVs (GEVs) host-pathogen interactions using primary mouse peritoneal macrophages model. Multiple methods electron microscopy, nanoparticle tracking analysis, proteomic assays,...
Combination therapy can be used for the treatment of fungal infections, especially those caused by antifungal-resistant fungi. In present study, in vitro interactions and mechanisms between fluconazole minocycline against Candida albicans were evaluated. The nature determined spectrophotometric method a checkerboard assay was interpreted using nonparametric models fractional inhibitory concentration index (FICI) percentages growth difference (ΔE). mechanism we evaluated potential activity on...
Abstract Background Giardia duodenalis is a prevalent intestinal pathogen causing giardiasis, condition characterized by diarrhea and frequently linked to malnutrition growth impairments in children. The virulence of Giardiavirus (GLV) may efficiently clear parasites from infected patients. However, we have limited understanding GLV transmission among species GLV-infected ’s impact on pathogenicity. Methods This study investigated extracellular vesicles (EVs) isolated via ultracentrifugation...
Background Swine represent one of the most economically significant livestock worldwide, and their intestinal microbial communities are crucial for maintaining physiological development regulating host metabolism. While extensive research has focused on fecal microbiota swine, investigations into across different segments remain limited. Objective This study aims to elucidate swine by analyzing luminal contents from segments, including duodenum, jejunum, ileum, cecum, colon. Methods We...
This research was intended to investigate the kinetics of polymeric immunoglobulin receptor (pIgR) and its ligand immunoglobulins (Ig) in snakehead (Channa argus) through different vaccine delivery methods. First, we employed Oxford Nanopore Technologies (ONT) sequencing technology acquire fish's complete transcriptome, full coding sequence (CDS) pIgR identified isolated transcriptome named ChpIgR. The CDS spanned 1251 base pairs, translating into a protein that consists 416 amino acids has...
Candida albicans is the most common candidal pathogen, causing serious systemic disease in immunocompromised patients. Azoles are widely applied and largely effective; however, they generally fungistatic clinically resistant isolates emerging increasingly. The present study provided vitro evidence using a chequerboard technique that amiodarone strongly synergistic with azoles against C. albicans, mean fractional inhibitory concentration indices of 0.01 high-percentage interactions 1250 %. A...
Abstract Background Giardia duodenalis is an extracellular protozoan parasite that causes giardiasis in mammals. The presentation of ranges from asymptomatic to severe diarrhea, and the World Health Organization lists it Neglected Diseases Initiative. Extracellular vesicles (EVs) are a key mediator intracellular communication. Although previous studies have shown G. intestinalis can regulate host’s innate immune response, role EVs (GEVs) triggering intestinalis- induced response remains be...
Giardia duodenalis , also known as lamblia or intestinalis is an important opportunistic, pathogenic, zoonotic, protozoan parasite that infects the small intestines of humans and animals, causing giardiasis. Several studies have demonstrated innate immunity-associated Toll-like receptors (TLRs) are critical for elimination G. ; however, whether TLR9 has a role in immune responses against infection remains unknown. In present study, various methods, including reverse...
The present study was conducted to investigate the prevalence and genotypes of Cryptosporidium in bats. A total 247 bats, belonging Rhinolophus sinicus, Rousettus leschenaultia, Aselliscus stoliczkanus, Hipposideros fulvus, were collected Yunnan Province, Southwestern China, intestinal tissues examined for infection by PCR amplification small subunit ribosomal RNA (SSU rRNA). overall rate 7.7% (95% CI, 4.5 11.0%), with R. sinicus having highest level at 9.5% 2.8 16.1%) followed A....
Skin photoaging, caused by prolonged exposure to ultraviolet (UV) radiation, manifests as intricate biological transformations, encompassing oxidative damage and structural alterations. Despite a growing need for effective interventions, the existing therapeutic repertoire treating skin photoaging remains constrained. Recent investigations have shifted focus towards application of hydrogels novel avenue addressing this concern. Various active substances can be combined with transdermal...
Abstract Background Cigarette smoke (CS) is a major risk factor for Chronic Obstructive Pulmonary Disease (COPD). Follistatin-like protein 1 (FSTL1), critical during embryogenesis particularly in respiratory lung development, novel mediator related to inflammation and tissue remodeling. We tried investigate the role of FSTL1 CS-induced autophagy dysregulation, airway Methods Serum specimens were obtained from COPD patients controls. Adult female wild-type (WT) mice, ± mice flox/+ exposed...