A5058465107- Hepatitis B Virus Studies
- Cervical Cancer and HPV Research
- Viral-associated cancers and disorders
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Eosinophilic Esophagitis
- Head and Neck Cancer Studies
- Blood donation and transfusion practices
- Blood groups and transfusion
- Gastric Cancer Management and Outcomes
- T-cell and Retrovirus Studies
- Viral Infections and Vectors
- Helicobacter pylori-related gastroenterology studies
- HIV/AIDS Research and Interventions
- Genital Health and Disease
- Cytomegalovirus and herpesvirus research
- SARS-CoV-2 detection and testing
- HER2/EGFR in Cancer Research
- Mosquito-borne diseases and control
- Viral Infections and Outbreaks Research
- Burn Injury Management and Outcomes
- Global Cancer Incidence and Screening
- Parvovirus B19 Infection Studies
- HIV, Drug Use, Sexual Risk
Marien Ngouabi University
2018-2025
University of Hassan II Casablanca
2024
Université de Tours
2024
Fondation Congolaise Pour La Recherche Médicale
2023
Université Hassan II Mohammedia
2014-2015
The geographic and evolutionary origins of the SARS-CoV-2 Omicron variant (BA.1), which was first detected mid-November 2021 in Southern Africa, remain unknown. We tested 13,097 COVID-19 patients sampled between mid-2021 to early 2022 from 22 African countries for BA.1 by real-time RT-PCR. By November-December 2021, had replaced Delta all sub-regions following a South-North gradient, with peak Rt 4.1. Polymerase chain reaction near-full genome sequencing data revealed genetically diverse...
Human herpesvirus 8 (HHV8) is endemic in Africa, although studies of this infection are rare Congo. We evaluated seroprevalence and HHV-8 diversity among people living with HIV. included 353 patients receiving highly active antiretroviral therapy. Antibodies against latency-associated nuclear antigen were detected by indirect immunofluorescence. In positive patients, we performed quantification blood saliva real-time PCR typing Sanger sequencing K1 open reading frame. was 19%, being male...
Caractériser le profil moléculaire du VHB dans les zones de forte endémicité Congo. Nous avons réalisé une étude transversale janvier à septembre 2013, soit période 9 mois, centres transfusion sanguine trois départements sud Congo (Pointe-Noire, Niari, Bouenza) et au laboratoire biologie LMVQ/ ETB/FST Mohammedia-Casablanca Maroc. Les variables étudiées ont été épidémiologiques biologiques. Des techniques d’extraction d’amplification génique conventionnelle spécifique utilisées partir don...
Background. Since the work of Band et al . in 1990 ( Proc. Natl. Acad. Sci. USA 87:463–467), several studies have suggested a possible link between pathogenesis breast cancer and viral infection. Infection with oncogenic HPV has been one viruses implicated cases worldwide. Objective. To investigate presence DNA archived paraffin-embedded at University Hospital Brazzaville to assess association infections clinicopathological features. Methods. A total 40 formalin-fixed (FFPE) biopsies were...
Introduction: Helicobacter pylori infection is a real health problem worldwide. It the most common chronic bacterial in world, and particularly prevalent developing countries. Objective: To determine frequency of to study epidemiological, clinical endoscopic characteristics associated with this Brazzaville. Patients Methods: This was descriptive cross-sectional conducted from January November 2020, i.e. 11 months. work focused on 100 symptomatic patients over 18 years old referred for upper...
Background: Viral hepatitis B is widespread globally and fetomaternal infection transmission a major public health problem. Few studies are available on HBV vertical in Brazzaville. The purpose of this study was to investigate the prevalence markers risk factors pregnant women. Methods: A cross-sectional carried out from January September 2014 among women attending antenatal clinics inBrazzaville.Relevant demographics infectious were obtained.HBV serological evaluated for HBsAg, HBeAg,...
Hepatitis B virus (HBV) infection is a major public health problem in the world. In Congo, studies on prevalence of HBV are common but HDV rare. Objective: Contribute to improve management and prevention infections. Patients Methods: This was descriptive cross-sectional study conducted from January August 2016 services various departments Congo at national laboratory Brazzaville. All patients with HBsAg surface antigen who were least 18 years old consented included. The HBs first tested by...
Introduction: Breast cancer is a heterogeneous disease with variety of morphological, molecular, treatment response and clinical outcome characteristics. The objective this work was to assess the epidemiological, histological, immunohistochemical molecular subtypes breast in women Republic Congo. Material Methods: We carried out cross-sectional descriptive study which took place from January 1, 2014 December 31, 2020. focused on 150 cases patients diagnosed at University Hospital Brazzaville...
Abstract Background and Aim Helicobacter pylori (Hp) infection is a real public health problem in the Congo. We aimed study histomolecular profile of Hp strains circulating Brazzaville, Congo, order to contribute improvement Hp‐infected patients country. Methods This was an analytical‐transversal carried out from January November 2020 (i.e. period 11 months) endoscopy centers Brazzaville as well molecular biology anatomopathology laboratories Pointe‐Noire Oyo. It involved 100 symptomatic...
Background: In mid-November 2021, the SARS-CoV-2 Omicron BA.1 variant was detected in Southern Africa, prompting international travel restrictions of unclear effectiveness that exacted a substantial economic toll. Methods: Amidst wave, we tested 13,294 COVID-19 patients 24 African countries between mid-2021 to early 2022 for and Delta variants using real-time reverse transcription-PCR tests. The diagnostic precision assays evaluated by high-throughput sequencing four countries. observed...
Sex workers experience elevated risks of sexual and gender-based violence (SGBV) from intimate partners, clients, community members that harms health human rights. While SGBV contributes to poorer reproductive (SRH) outcomes among sex workers, including immunodeficiency virus (HIV) vulnerabilities, stigma targeting reduces SRH service access uptake. The Congo Republic is an exemplar context address toward workers. workers’ HIV prevalence (8.1%) in double the national prevalence, yet research...
Objectives. The HTLV-1 infection persists for life, remaining as asymptomatic viral reservoirs in most patients, ensuring the chain of transmission, but around 4% develop adult T-cell leukemia/lymphoma (ATLL). is an oncogenic retrovirus that transforms CD4+ T lymphocytes and deregulates lymphoproliferative pathways contribute to development ATLL. To achieve cell transformation, retroviruses use proto-oncogene capture transduction, with proviral integration disrupting expression tumor...
The search for new biomarkers predictive of type 2 diabetes currently constitutes a research avenue in Bioclinical. Total homocysteine remains preferred target due to its involvement the occurrence degenerative complications diabetics. aim this work was study hyperhomocysteinemia and other biochemical markers associated with T2D Congolese population. This an analytical case-control carried out between October 2022 2023. population consisted 150 subjects including 100 patients 50 control...
Human herpesvirus 8 (HHV8) is rarely studied in Congo, despite its prevalence Africa. Among healthy individuals, HHV-8 does not always lead to a life-threatening infection; however, immunocompromised it could more severe disease. The distribution of genotypes varies depending on ethnicity and geographic region.
The aim of this study was to identify the molecular prevalence high-risk HPV infection and distribution genotypes present in normal cytology, as well determine vaccination status our population.
Hepatitis B virus infection is a major global health problem, particularly in HIV-infected patients and increases the risk of liver damage. The purpose this study was to assess HBV prevalence genotypes among Brazzaville, Republic Congo. This cross-sectional conducted HIV-positive attending an outpatient treatment center for HIV/AIDS from June 2018 February 2020. Blood samples were screened HBsAg by ELISA determined phylogenetic inference. Data analysis done using SPSS V.21.0 P value less...
Crimean-Congo hemorrhagic fever virus (CCHFV) is the causative agent of (CCHF), a highly contagious and potentially fatal emerging disease. We assessed CCHFV seroprevalence by conducting serological survey two cohorts from Brazzaville, Congo Bamako, Mali. retrospectively screened 581 sera samples, including 352 monitoring centers for people living with HIV (PLWH) in Brazzaville 229 provided Blood Transfusion Center at Gabriel Touré Hospital Bamako. An ELISA kit (ID Screen® CCHF Double...
Summary: There is no evidence for comorbidity diabetes and hepatitis C virus infection in the Congo. The aim of this work was to determine seroprevalence molecular biodiversity HCV order contribute improving management Congolese diabetics. Patients methods: It a cross-sectional study that took place from 1 February 30 September 2018 at Brazzaville University Hospital, Diabcare Health Center Adolphe Cissé Hospital Pointe-Noire. concerned diabetic patients followed Pointe-Noire agreeing study,...