A5042222966- Tuberculosis Research and Epidemiology
- HIV/AIDS Research and Interventions
- Mycobacterium research and diagnosis
- HIV/AIDS Impact and Responses
- HIV, Drug Use, Sexual Risk
- Infectious Diseases and Tuberculosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Diagnosis and treatment of tuberculosis
- Adolescent Sexual and Reproductive Health
- Sex work and related issues
- SARS-CoV-2 and COVID-19 Research
- Heme Oxygenase-1 and Carbon Monoxide
- Syphilis Diagnosis and Treatment
- Mobile and Web Applications
- COVID-19 Pandemic Impacts
- SARS-CoV-2 detection and testing
- HIV Research and Treatment
- Rabies epidemiology and control
- Reproductive tract infections research
- Hepatitis C virus research
- COVID-19 diagnosis using AI
- Lung Cancer Diagnosis and Treatment
- ICT in Developing Communities
- Vaccine Coverage and Hesitancy
- Hepatitis B Virus Studies
Laboratoire National de Santé Publique du Congo
2022
Fondation Congolaise Pour La Recherche Médicale
2014-2021
Université Joseph Ki-Zerbo
2012-2019
German Center for Infection Research
2017
Research Center Borstel - Leibniz Lung Center
2017
Marien Ngouabi University
2017
Université de Yaoundé I
2017
University of Tübingen
2017
Centre Hospitalier et Universitaire de Brazzaville
2017
To evaluate the prevalence of toxoplasmosis and rubella among pregnant women at Ouagadougou in Burkina Faso.All patient sera were tested for anti-IgG using commercial ELISA kits (Platelia™ Rubella IgG Platelia™ Toxo IgG). The presence anti-rubella anti-toxoplasmosis IgM serum samples was Platelia IgM.Among all rubella, their 20.3% 77.0%, respectively. Pregnant age group 18-25 years showed highest frequency (34.5%) (84.6%). anti-toxoplasma decreased between 2006 2008 from 32.7% to 12.1% 84.6%...
Abstract Tuberculosis is a leading cause of illness and death in Congo. No data are available about the population structure transmission dynamics Mycobacterium tuberculosis complex strains prevalent this central Africa country. On basis single-nucleotide polymorphisms detected by whole-genome sequencing, we phylogenetically characterized 74 MTBC isolates from Brazzaville, capital The diversity study was high; most belonged to Euro-American lineage, which split into Latin American...
The diagnosis of pulmonary tuberculosis (PTB) and smear-negative (SNPT) in resource-limited countries is often solely based on clinical signs, chest X-ray radiography sputum smear microscopy. We investigated currently used methods for the routine SNPT Republic Congo (RoC) among TB suspected patients. specific case HIV positive patients was also studied. A cross-sectional study conducted at anti-tuberculosis center (CAT) Brazzaville, RoC. Tuberculosis suspects were examined physical signs TB....
The Republic of Congo is on the World Health Organization (WHO) list 'high burden' countries for tuberculosis (TB) and HIV. TB leading cause death among HIV-infected patients in Congo. In this viewpoint, available data HIV are reviewed, gaps bottlenecks that National Control Program (NTCP) faces discussed. Furthermore, priority requirements developing implementing collaborative service activities identified. control programs operate as distinct entities with separate case management plans....
Vaccines are urgently needed to control the coronavirus disease 2019 (COVID-19) pandemic. The aim of this study was determine acceptance and willingness purchase a hypothetical COVID-19 vaccine in general population Aceh, holistic Shariah law implementation province Indonesia. An online cross-sectional conducted using quota sampling technique between 1 24 September 2021. To acceptance, respondents were asked if they willing accept vaccines with combinations either 50% or 95% effectiveness 5%...
Abstract Background In the Republic in Congo, national algorithm for diagnosis of pulmonary tuberculosis (TB) relies on Ziehl-Neelsen (ZN) sputum smear microscopy, chest X-ray radiography (CXR) and clinical symptoms. Microscopy positive TB (MPT+) is defined as symptoms a ZN smear. negative (MPT-) TB, but CXR changes consistent with TB. The present cross-sectional study was designed to determine prevalence MPT individuals among HIV presenting an ambulatory treatment center (CTA) Brazzaville....
This study was carried out to identify factors affecting the acceptability of voluntary HIV testing among pregnant women in a semi-rural city, Gamboma, Republic Congo. A cross-sectional conducted between January and September 2012. Pregnant attending antenatal heath care at an integrated health center were enrolled after informed consent followed through testing. Among 136 participants, 98 (72 %) accepted pre-test counseling. Women with basic education, those who cited blood transfusion as...
To evaluate efficiency of HAART in the prevention mother to child HIV transmission.A longitudinal study was conducted on 1 300 women attending antenatal service at Saint Camille Medical Centre from September 2010 July 2011. The status mothers determined by rapid tests and ELISA. Discordant results were confirmed real-time PCR. PCR used determine children born HIV-positive mothers.Among pregnant tested for HIV, 378 seropositive. Mothers predominantly housewives (69.7%), their mean age...
Abstract Background There is paucity of data on the prevalence and distribution multidrug- Resistant-Tuberculosis (MDR-TB) in Republic Congo. Among challenges resides implementation a robust TB resistance diagnostic program using molecular tools. In resource limited settings there need to gather enable prioritization actions. The objective this study was implement tools as best diagnosing MDR XDR-TB among presumptive tuberculosis patients referred reference hospital Makelekele Brazzaville,...
Introduction: Due to the existence of a variety types non-venereal syphilis caused by related T. pallidum, regular serological testing such as Rapid Plasma Reagin (RPR) and Chemiluminescent Microparticle Immunoassay Technique (CMIA) are often unable differentiate venereal from non- one, hence, interest in use molecular biology for confirmation diagnosis Treponema pallidum subspecies pallidum. Objective: The study is designed assess effectiveness PCR methods subsp among blood donors Burkina Faso.
Background: The rate of HIV infection in the Republic Congo is 5%. Training on HIV/AIDS not formally included university curriculum. We evaluated students' knowledge and attitudes about Faculty Health Sciences Brazzaville. Methods: All 3rd year students medicine, public health biomedical sciences, plus 4th, 5th 6th years medicine completed survey through a questionnaire developed by research unit. Results: A total 159 participated survey. willingness to work with people living take care them...
Sex workers experience elevated risks of sexual and gender-based violence (SGBV) from intimate partners, clients, community members that harms health human rights. While SGBV contributes to poorer reproductive (SRH) outcomes among sex workers, including immunodeficiency virus (HIV) vulnerabilities, stigma targeting reduces SRH service access uptake. The Congo Republic is an exemplar context address toward workers. workers’ HIV prevalence (8.1%) in double the national prevalence, yet research...
Context and objective. Leprosy is a major problem in the Democratic Republic of Congo (DRC), ranked 5th world 1st Africa for leprosy endemic. The objective this study was to describe socio-demographic profiles people affected by leprosy-related disabilities Kongo-Central, focusing on age, gender, socio-economic status, access care stigma. Methods. We conducted retrospective Kongo-Central province, using data from 2010 2020. population included persons registered monitoring registers, with...
Introduction: The HIV infection rate has fallen sharply among pregnant women in the Republic of Congo (ROC), declining from 4.2% 2003 to 2.5% 2013. However, vertical transmission observed is about 34% and mortality children born HIV-positive mothers high. Since implementation program for Prevention Mother-to-Child Transmission (PMTCT) 2002, all prevention activities are based on collaboration with Ambulatory Treatment Centers (CTA) Kento-Mwana project. Ministry Health ROC process...
Setting: Xpert MTB/Rif has become an integral part of tuberculosis diagnostic algorithms in many low- and middle-income countries no published data was retrieved regarding the accuracy MTB/RIF sputum smear-negative pulmonary TB RoC. Objectives: This study aimed at determining diagnosing keeping AFB microscopy as gold standard. Design: For 4 months, one morning smear performed for every suspect (cough lasting >3 weeks, defined Congolese’s national guidelines) with GeneXpert. Results: Of 90...
We conducted a study to evaluate the sensitivity (Se), specificity (Sp), positive predictive value (PPV), and negative (NPV) of five serologic tests. Subjects with or COVID-19 polymerase chain reaction (PRC) test results were tested each serological The compared reference PCR test. For tests evaluated, Se ranged from 55.0% 70.0% Sp 67.2% 86.2%. PPV 53.2% 80% NPV 75.0% One test, Wantai, had better sensitivity. None performance values more than 90% in entire sample. In symptomatic cases,...
Abstract Background Tuberculosis (TB) remains a public health problem and early detection of drug resistance is crucial to prevent transmission drug-resistant TB avoid mortality. There paucity data on the prevalence distribution MDR-TB at Republic Congo. However, challenges establishing robust testing program are significant. In resource limited settings there need gather enable prioritization actions. The objective this study was characterize epidemiological profile MDR XDR-TB among...
Abstract Zoonotic tuberculosis is a major form of TB affecting humans and many animal species. Infected cattle pose threat to public health. The aim the study was characterize risks exposure bovine by slaughterhouse workers in Brazzaville. A survey carried out among 57 from three slaughterhouses Brazzaville (Mpila, Kanga Mbanzi La Fougère) using questionnaires field observations. results profile revealed that majority staff are made up mainly people over 40 years old (40.6 ± 8.4) i.e. 50.9%...