A5043559906- SARS-CoV-2 and COVID-19 Research
- Hepatitis B Virus Studies
- COVID-19 Clinical Research Studies
- Knowledge Societies in the 21st Century
- Hepatitis C virus research
- Educational Innovations and Technology
- Vector-Borne Animal Diseases
- T-cell and Retrovirus Studies
- Animal Disease Management and Epidemiology
- Blood donation and transfusion practices
- Hepatitis Viruses Studies and Epidemiology
- Educational Games and Gamification
- Liver Disease and Transplantation
- Viral Infections and Vectors
- E-Learning and Knowledge Management
- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 detection and testing
- Engineering and Information Technology
- Mosquito-borne diseases and control
- Blood groups and transfusion
- Platelet Disorders and Treatments
- Teaching and Learning Programming
- Animal Virus Infections Studies
- Parvovirus B19 Infection Studies
- Parallel Computing and Optimization Techniques
Central Bank of Argentina
2016-2024
Universidad Nacional de Córdoba
2016-2024
Clínica Alemana
2024
Universidad Católica de Córdoba
2024
Universidad Abierta Interamericana
2016-2023
University of Buenos Aires
2020
Ministerio de Salud
2017
Abstract Background and Objectives Nucleic acid amplification testing (NAT), in blood services context, is used for the detection of viral parasite nucleic acids to reduce transfusion‐transmitted infections. This project reviewed NAT screening donations globally. Materials Methods A survey on usage, developed by International Society Blood Transfusion Working Party Transfusion‐transmitted Infectious Diseases (ISBT WP‐TTID), was distributed through ISBT WP‐TTID members. Data were analysed...
Abstract The range of vaccines developed against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) provides a unique opportunity to study immunization across different platforms. In single-center cohort, we analyzed the humoral and cellular immune compartments following five disease 2019 (COVID-19) spanning three technologies (adenoviral, mRNA inactivated virus) administered in 16 combinations. For adenoviral inactivated-virus vaccines, heterologous combinations were generally...
Arthropod-borne viruses (arboviruses) count among emerging infections, which represent a major challenge for transfusion safety worldwide. To assess the risk of arboviruses-transmission by (ATT), we performed survey to evaluate potential threat safety. Samples were retrospectively and randomly collected from donors who donated during peak dengue incidence in Cordoba (years: 2016 2019-2022). A cost-efficient strategy molecular screening was implemented with nucleic acid test (NAT) configured...
Molecular and epidemiological studies of transmission routes risk factors for infection by HTLV-1 are extremely important in order to implement control measures, especially because the high prevalence several regions world. San Salvador de Jujuy, Northwest Argentina, is a highly endemic area foci tropical spastic paraparesis/HTLV-1-associated myelopathy.To gain further insight into role intrafamilial region Argentina.Cross-sectional study Argentina. Epidemiological data blood samples were...
Background In Argentina, with the aim of moving to a safe supportive and inclusive National Blood System, in September 2015 Ministry Health stipulated that eligibility criteria for blood donation should only take into account so‐called 'risk practices', focusing on 'gender‐neutral' policy. The this study is demonstrate impact such regulation prevalence STI population donors through analysis scientific evidence obtained from 174 074 large central region country, focused regional Bank 6‐year...
Abstract Background and Objectives Nucleic acid‐amplification testing (NAT) is used for screening blood donations/donors blood‐borne viruses. We reviewed global viral NAT characteristics NAT‐yield confirmatory by operators. Materials Methods during 2019 was surveyed internationally the International Society of Blood Transfusion Working Party Transfusion‐Transmitted Infectious Diseases. Reported are presented herein. Results mainly performed under government mandate. Human immunodeficiency...
BACKGROUND Results from 10‐year experience using nucleic acid test (NAT) screening in a blood bank of Córdoba are presented, showing the first data on prevalence recent hepatitis B virus (HBV) infections and occult HBV (OBIs) Argentina. STUDY DESIGN AND METHODS Molecular was performed by COBAS AmpliScreen human immunodeficiency Type 1 (HIV‐1) Version 1.5 C (HCV) 2.0 TaqScreen MPX (Roche Systems). To characterize OBI, additional molecular serologic assays were performed. RESULTS As results...
Abstract Novel adjuvants are highly desired to improve immune responses of SARS‐CoV‐2 vaccines. This work reports the potential stimulator interferon genes (STING) agonist adjuvant, cyclic di‐adenosine monophosphate (c‐di‐AMP), in a vaccine based on receptor binding domain (RBD). Here, mice immunized with two doses monomeric RBD adjuvanted c‐di‐AMP intramuscularly were found exhibit stronger compared vaccinated aluminum hydroxide (Al(OH) 3 ) or without adjuvant. After immunizations,...
A retrospective, cross-sectional study was conducted to determine the frequency of human parvovirus B19 (B19V) infected individuals, viral loads and immunity among blood donors from Argentina, in a post-epidemic outbreak period. B19V DNA specific IgG were tested minimum samples attending bank at Córdoba, 2014. Anti-B19V IgM determined B19V-positive plasma samples. Seven 731 (0.96%) resulted positive, corresponding individuals aged 32-53 years, four them repeat donnors three first-time...
The aim of this study is to show that human T-cell lymphotropic virus type 2 (HTLV-2) infection produces symptoms resembling those described for HTLV-1-associated myeloneuropathy and highlight the role sexual transmission in silent dissemination HTLV-2.Patient samples were tested by particle agglutination indirect immunofluorescence assay. HTLV was defined molecular techniques. Nucleotide sequence analysis HTLV-2 long terminal repeat region, T cell CD3/CD4 CD3/CD8 counts typing leucocyte...
Hepatitis E virus (HEV) is the main cause of enteric acute viral hepatitis worldwide. In this epidemiological framework, it has become a threat to blood safety and relevant issue for transfusions. However, there paucity data regarding prevalence HEV infection. The aim study was determine seroprevalence in donors from different regions Argentina.Serum samples 391 individuals attending five donor centers located Argentina were analyzed anti-HEV IgG IgM.Overall, detected 44 out (11.3%) samples....
Abstract Background To analyze the infectious extent of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) in different settings where prevention strategies are critical to limit infection spread, we evaluated SARS-COV-2 viability guide public health policies regarding isolation criteria and control. Methods We attempted viral 82 nasopharyngeal swabs from 72 patients with confirmed infection. Study population was divided into four groups: (i) Patients during first week symptoms;...
Features of Bordetella pertussis, spp. infection and whopping cough inCórdoba province, ArgentinaIntroduction: Whooping is a re-emerging in the world Latin America.Objective: It was considered relevant to investigate clinical epidemiological profile spp.and pertussis Córdoba Argentina; evaluating, at same time, co-infection with virus producing respiratory infections that may be confused whooping cough.Material Methods: All suspected cases were studied by Polimerase Chain Reaction,...
<b>Introduction:</b> Since anti-D immunoprophylaxis given to D-negative pregnant women is a blood product, donations have an impact on the availability of prophylactic doses. The Pan American Health Organization reported, in June 2017, that less than half donors are volunteers Latin America and Caribbean. In these countries, guidelines for use prophylaxis still controversial. aim this study was demonstrate convenience simple cost-effectivene non-invasive prenatal diagnostic assay...
In some areas of Argentina endemic for human T-lymphotropic virus type 1 (HTLV-1), tropical spastic paraparesis is frequent in subjects who lack antibodies against the virus; however, relevance this seronegative status country has not been investigated. neighboring countries, HTLV-1 described patients with different diseases; data regarding features carriers are scarce. We investigated 124 relatives 28 infected from an area Northwest Argentina. Blood samples and clinical/epidemiological were...
Abstract We present the case of a breakthrough infection by hepatitis B virus (HBV), intending to warn about challenge that HBV represents for transfusion safety. Virological markers were assayed during blood donor screening detection HBsAg, anti‐HBc, and viral nucleic acid (HBV DNA) test (NAT). Additionally, samples analyzed immunoglobulin M HBeAg, anti‐HBe, anti‐HBs. A first‐time repeatedly tested positive DNA NAT nonreactive HBV‐serological infection. He stated having completed anti‐HBV...
Introduction: Placenta accreta spectrum (PAS) refers to the abnormal adherence of placental trophoblast uterine myometrium. Several conditions are associated with its development. Ultrasound is imaging modality choice for antenatal diagnosis. In cases doubt, magnetic resonance (MR) plays a leading role, due high performance, and contributes surgical planning. The final diagnosis made in surgery, subsequent confirmation by pathology. objective this article present case placenta increta,...
Saint Louis encephalitis virus (SLEV) re-emergence and its geographical expansion, evidenced by emergence in previously unaffected areas, have raised significant public health concerns. We aimed to show the usefulness of haemovigilance as an effective tool fill arboviruses surveillance gaps track trends identify hotspots.