A5101688834- Advanced Computational Techniques and Applications
- Industrial Technology and Control Systems
- Advanced Sensor and Energy Harvesting Materials
- Protein Hydrolysis and Bioactive Peptides
- Atherosclerosis and Cardiovascular Diseases
- Inflammasome and immune disorders
- Fungal Biology and Applications
- Simulation and Modeling Applications
- Melanoma and MAPK Pathways
- COVID-19 Clinical Research Studies
- Quinazolinone synthesis and applications
- Genomics, phytochemicals, and oxidative stress
- Immunotherapy and Immune Responses
- Tannin, Tannase and Anticancer Activities
- Inflammation biomarkers and pathways
- Chromatography in Natural Products
- Phytochemistry and Biological Activities
- Stress Responses and Cortisol
- Seaweed-derived Bioactive Compounds
- Ginseng Biological Effects and Applications
- Selenium in Biological Systems
- Advanced Manufacturing and Logistics Optimization
- Research studies in Vietnam
- Grey System Theory Applications
- Biochemical and biochemical processes
Fudan University Shanghai Cancer Center
2025
Nanjing Forestry University
2024
Anhui Agricultural University
2024
Sichuan Academy of Agricultural Sciences
2020-2022
Fudan University
2020-2022
University of South China
2017-2021
Dalian Medical University
2021
Chongqing Medical University
2021
Second Affiliated Hospital of Chongqing Medical University
2021
Infinitus (China)
2012-2020
Oxymatrine, a quinolizidine alkaloid isolated from the traditional Chinese herb Sophora flavescens Aiton, has been demonstrated to exert anti‑inflammatory and atherosclerotic effects, but molecular mechanism yet be elucidated. Accumulating evidence indicates an important role of NLR family pyrin domain containing 3 (NLRP3) inflammasome‑mediated pyroptosis in pathogenesis atherosclerosis. The present study was undertaken investigate whether oxymatrine attenuates oxidized low‑density...
Abstract The molecular weight of the polysaccharide and chemical groups it contains has an important influence on its biological activity, relatively low polysaccharides may have better antioxidant activity. Polysaccharides isolated from fruiting bodies Morchella sextelata (MSP) were treated by γ-irradiation at 10, 100 1000 kGy doses, physicochemical properties activity irradiated MSP investigated. Microscopic observation under a scanning electron microscope (SEM) showed that breakage pores...
Acute diarrhoea continues to be a leading cause of morbidity, hospitalisation, and mortality worldwide, probiotics have been proposed as complementary therapy in the treatment acute diarrhoea. The goal this study is assess efficacy safety three combined probiotic strains, Bifidobacterium lactis Bi-07, Lactobacillus rhamnosus HN001, acidophilus NCFM, an adjunct rehydration watery hospitalised children. Eligible diarrheal children were randomised into intervention group (IG, n=96, conventional...
Previous studies have shown that cyclooxygenase-2, a key enzyme converts arachidonic acid to prostaglandins, is involved in anxiety and cognitive processes, but few investigated the effects of chronic administration cyclooxygenase-2 inhibitors on anxiety, learning memory under normal physiological conditions. The aim study was investigate parecoxib, inhibitor, behavior performance conditions explore possible neural mechanism underlying parecoxib-mediated effects.Adult male ICR mice were...
Aflatoxin B
Morels (Morchella spp.) are a genus of edible fungi with important economic and medicinal value. In this study, novel peptide (MIPP) was extracted from the fruiting bodies Morchella importuna using gel filtration chromatography. Structural analysis showed that molecular mass MIPP is 831 Da, it has simple amino acid sequence: Ser-Leu-Ser-Leu-Ser-Val-Ala-Arg. To explore antitumor activity MIPP, effect on HeLa cell apoptosis underlying preventative mechanisms were investigated. Results reduced...
Abstract According to previous studies, oxidative stress is a leading cause of dopaminergic neuron death and may contribute the pathogenesis Parkinson's disease (PD). In current study, we used chromatography gel filtration identify novel peptide ( Lignosus rhinocerotis [LRP]) from sclerotium (Cooke) Ryvarden. Its neuroprotective effect was evaluated using an in vitro PD model constructed by 6‐hydroxydopamine (6‐OHDA)‐stimulated apoptosis PC12 cells. The molecular weight LRP determined as...
Hypoxic-ischemic encephalopathy (HIE) is a prominent cause of neuronal damage and neonatal death, effective treatment strategies remain limited. In prior investigation, we purified novel peptide (designated MIP-15) from the rare mushroom<em> Morchella importuna</em>, demonstrating its notable free radical scavenging activity. Nevertheless, potential neuroprotective role MIP-15 in hypoxic-ischemic brain (HIBD) underlying mechanism elusive. The purpose this study was to evaluate whether exerts...
Ginsenoside Rg_3 is widely used in clinical practice as an anti-tumor adjuvant drug, but its application limited due to poor oral absorption. In this study, we intended construct a ginsenoside nanostructured lipid carrier modified by the pullulan(PUL-Rg_3-NLC) improve adhesion properties of Rg_3, promote drug uptake and efficacy. PUL-Rg_3-NLC was characterized morphology, particle size Zeta potential. vivo characteristics were evaluated gavage tests, results verified from multiple...
An evaluation index system including three aspects and ten indexes is established. For the scientific development of oilfield enterprise, optimal selection science & technology projects has great significance which are mostly uncertain. Based on presentation interval number indexes, sorting model, TOPS IS model projection was constructed, a Borda method proposed to combine achieve consistent results. example shows that can improve scientificity efficiency effectively.
Objective To study the effects of vitamin K2 on hepatoma-derived growth factor(HDGF) in a hapatoma cell line. Methods Different concentrations were added to culture plates hepatoma cells. The expression levels HDGF cells detected using immunohistochemistry. Results HDGF-positive nucleus and cytoplasm shown as clear brown particles. rate was 79%, 49% 23% control group, 15 μmol/L K2- treated group 30 K2-treated respectively. Conclusion Vitamin could significantly inhibit...