A5059194662- Dementia and Cognitive Impairment Research
- Alzheimer's disease research and treatments
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Cancer Diagnosis and Treatment
- Neuroinflammation and Neurodegeneration Mechanisms
- Tracheal and airway disorders
- Health, Environment, Cognitive Aging
- Neonatal Health and Biochemistry
- Metabolomics and Mass Spectrometry Studies
- Bioinformatics and Genomic Networks
- Groundwater flow and contamination studies
- Head and Neck Cancer Studies
- Psychosomatic Disorders and Their Treatments
- Erythrocyte Function and Pathophysiology
- Parkinson's Disease Mechanisms and Treatments
- Global Cancer Incidence and Screening
- Vascular Anomalies and Treatments
- Face and Expression Recognition
- Water Quality and Resources Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Statistical Methods and Inference
- Machine Learning in Bioinformatics
Alzheimer’s Disease Neuroimaging Initiative
2023-2024
Albany Medical Center Hospital
2020-2023
Wisconsin Geological and Natural History Survey
2017-2021
St Vincent's Hospital
2005-2017
University of Wisconsin System
2017
Institut Gustave Roussy
2013
St. Vincent's Birmingham
2000-2006
Columbia University Irving Medical Center
1980
New York University
1980
The Royal Melbourne Hospital
1980
<h3>Importance</h3> Neurofibrillary tangles composed of aggregated tau protein are one the neuropathological hallmarks Alzheimer disease (AD) and correlate with clinical severity. Monoclonal antibodies targeting may have potential to ameliorate AD progression by slowing or stopping spread and/or accumulation pathological tau. <h3>Objective</h3> To evaluate safety efficacy monoclonal anti-tau antibody semorinemab in prodromal mild AD. <h3>Design, Setting, Participants</h3> This phase 2...
Artificial stone is an increasingly popular material used to fabricate kitchen and bathroom benchtops. Cutting grinding artificial associated with generation of very high levels respirable crystalline silica, the frequency cases severe silicosis this exposure rapidly increasing.To report characteristics a clinical series Australian workers stone-associated silicosis.Respiratory physicians voluntarily reported identified in their practices. Physicians provided information including...
Abstract Background: The aim of this study was to describe the activity a lung cancer multidisciplinary clinic (MDC) and examine whether model clinical practice results in adherence best‐practice guidelines. Methods: Prospective analysis demographic data 431 patients referred MDC for management known or suspected thoracic malignancy. Adherence documented clinically relevant guideline recommendations concerning timely evidence‐based management. Results: Of patients, 257 were diagnosed with...
Optimal management of nonsmall cell lung cancer (NSCLC) depends on tissue diagnosis and accurate staging. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is minimally invasive provides cytological confirmation malignant mediastinal disease. The aim was to assess the accuracy EUS-FNA in cases enlarged lymphadenopathy (LN) unknown aetiology staging NSCLC. A total 52 consecutive patients with stage I–IIIb NSCLC or LN underwent EUS-FNA. Negative results were confirmed a surgical...
Erythrocyte protoporphyrin content is increased in several human and veterinary disorders which heme synthesis disrupted. The nature of the defect determines whether zinc protoporphyrin, unchelated (free) or both are present erythrocytes. Extraction into acetone/water (80/20 by vol) a simple, rapid technique each species delivered solution without removing from protoporphyrin. ratio to total concentration correlated significantly with fluorescence emission intensities at peak an isosbestic...
Lung cancer accounts for significant morbidity and mortality worldwide. The effect of recent changes in demographics management on outcomes Australia has not been clearly defined.To compare three consecutive lung cohorts to evaluate emergent differences diagnosis, mortality.For comparative analysis, 2119 patients were divided into successive cohorts. Current death data sought from the Victorian Cancer Registry.Age at mode presentation pathology did significantly differ between groups....
We present the case of a 30-year-old non-smoker who presented with unexplained, massive hemoptysis and was diagnosed rare vascular malformation.
Mediastinal endoscopic ultrasound guided fine needle aspiration (EUS-FNA) is a recognized diagnostic and staging procedure for non-small cell lung carcinoma (NSCLC). The aim of this study was to report the experience mediastinal EUS in an Australian tertiary hospital.A retrospective review conducted on all patients undergoing from February 2002 until August 2007 at St Vincent's Hospital, Melbourne. Data were obtained databases Hospital patient endoscopy reports. results EUS-FNA compared with...
Background The association between socio‐economic status ( SES ) and lung cancer is internationally established, but in Australia this relationship remains ill defined. Aims To examine the , place of residence outcomes a large Australian cohort. Methods A total 2369 consecutive patients managed by St Vincent's Hospital multidisciplinary meeting 2001 2014 were included. Postcode data stratified participants Socio‐economic indexes for areas, validated measure geographical location, an...
The Northeast Groundwater Management Area of Wisconsin, USA contains two major cones depression in a confined sandstone aquifer. Each cone is centered near cities that have used groundwater for over 100 years. Near one these (Green Bay), episodic changes the development and surface water resources during this period resulted to potentiometric surface. On occasions, roughly 50 years apart, reductions withdrawals from construction pipelines drawing Lake Michigan. In each case, rapid recovery...
The aim of the present study was to determine treatment practices for spontaneous pneumothorax (PTX) in Australia.A questionnaire regarding PTX posted all medically qualified members Thoracic Society Australia and New Zealand resident Australia.Fifty-three per cent (n = 226) questionnaires were returned. Twenty-one responses judged be informal rejected from analysis. results indicate a general agreement small large but wide variation intermediate size.Opinion optimal size found vary...
Abstract Communication of hydrologic data to the public can be improved by connecting places they represent. In our example communication, we coupled with simultaneously collected video as both a scientific and engagement tool. This note presents method for collecting spatially temporally dense datasets water‐quality geophysical on small streams lakes, displaying in user‐friendly format using commercially available software. With this method, multiple instruments are mounted canoe controlled...