A5066743778- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- EEG and Brain-Computer Interfaces
- Retinal Development and Disorders
- Ginkgo biloba and Cashew Applications
- Botulinum Toxin and Related Neurological Disorders
- Retinal Diseases and Treatments
- Genetic Neurodegenerative Diseases
- Cerebrospinal fluid and hydrocephalus
- Ophthalmology and Eye Disorders
- Venomous Animal Envenomation and Studies
- Autism Spectrum Disorder Research
- Obsessive-Compulsive Spectrum Disorders
- SARS-CoV-2 and COVID-19 Research
- Neurological and metabolic disorders
- Epilepsy research and treatment
- Peripheral Neuropathies and Disorders
- Balance, Gait, and Falls Prevention
- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- Stuttering Research and Treatment
- Olfactory and Sensory Function Studies
- Dementia and Cognitive Impairment Research
- Restless Legs Syndrome Research
- Myasthenia Gravis and Thymoma
University of Catania
2019-2025
Ospedale G.F. Ingrassia
2023
Tecnologie Avanzate (Italy)
2021
University of Bari Aldo Moro
2020
Sapienza University of Rome
2020
Ospedale Civile di Voghera
2020
University of Cagliari
2020
To perform a simultaneous evaluation of potential risk/protective factors Parkinson disease (PD) to identify independent factors, assess interaction among and determine whether identified risk predict etiologic subtypes PD.We designed large case-control study assessing 31 protective/risk PD, including environmental lifestyle comorbid conditions, drugs. The enrolled 694 patients with PD 640 healthy controls from 6 neurologic centers. Data were analyzed by logistic regression models, additive...
A thinning of intraretinal layers has been previously described in Parkinson's disease (PD) patients compared to healthy controls (HCs). Few studies evaluated the possible correlation between retinal thickness and microvascularization. Thus, here we assessed microvascular pattern early PD HCs, using, respectively, spectral-domain optical coherence tomography (SD-OCT) SD-OCT-angiography (SD-OCT-A), more interestingly, a pattern. Patients fulfilling criteria for clinically...
Abstract Non-motor symptoms (NMS) and fluctuations (NMF) in Parkinson’s Disease (PD) are common, involving several domains affecting quality of life. Aim the study is to estimate burden NMF PD patients evaluate possible gender effect. fulfilling MDS-PD diagnostic criteria attending “Parkinson’s Movement Disorders Centre” University Catania were evaluated using Non-Motor Fluctuations Assessment (NoMoFA) Questionnaire. NoMoFA items also grouped into following domains: cognitive, mood,...
Essential tremor (ET) represents a heterogeneous condition which may overlap with Parkinson disease (PD) even at early stages, by sharing some subtle clinical aspects. Longstanding ET demonstrated also higher risk of developing PD, especially Tremor-dominant (TD-PD) phenotype. Therefore, differential diagnosis between and PD could be quite challenging. Optical coherence tomography (OCT) has been recognized as reliable tool to assess the retina proxy neurodegeneration. We aimed explore...
Study Objectives: Few studieshave analyzed theprevalenceofisolated rapid eye movementsleep behavior disorder (RBD) giving differentestimates.Aim ofthestudy was to estimate the prevalence of isolated RBD in city Catania.Methods: A 3-stage design adopted.Participants attending offices general practitioners Catania were screened with Single Question Screen questionnaire (Stage I).Positive participants interviewed by phone and, if suspected RBD, invited for clinical examination a movement...
Neurodegenerative diseases are common causes of impaired mobility and cognition in the elderly. Among them, tauopathies α-synucleinopathies were considered. The neurodegenerative processes relative differential diagnosis addressed through a qEEG non-linear analytic method. Study aims to test accuracy power law exponent β applied EEG differentiating explore differences neuronal connectivity among different based on β. N = 230 patients with tauopathy or α-synucleinopathy at least one...
During the worldwide mass vaccination campaign against SARS-CoV-2, multiple side effects have been observed. We described case of a patient who developed pure sensitive chronic inflammatory axonal polyneuropathy (CIAP) in close temporal relationship with administration BNT162b2 (Pfizer®) vaccine. An 82-year-old woman lower limb sensory loss and "pricking" associated marked gait imbalance after she had received her second dose Pfizer-BioNTech COVID-19 At electroneurographic examination, motor...
The neuropsychological profile of progressive supranuclear palsy (PSP) patients is mainly characterized by executive dysfunction, but the relationship between latter and midbrain atrophy still unclear.The aims study were to investigate which test evaluating functioning more frequently impaired in PSP evaluate midbrain-based MRI morphometric measures dysfunction.PSP who had undergone a battery assessing with Frontal Assessment Battery (FAB), phonemic verbal fluency F-A-S, Raven's Progressive...
ABSTRACT Background Differential diagnosis between idiopathic normal pressure hydrocephalus (iNPH) associated with parkinsonism (iNPH‐P) and Parkinson's disease (PD) may prove difficult when evaluating patients early parkinsonism. The objective of this study was to evaluate differences in mobility during standardized tasks iNPH‐P PD. Methods We selected 21 pharmacologically untreated PD patients. They all performed the instrumented Timed Up Go test at time diagnosis. Results Turning showed...
Background: Polytherapy and the anticholinergic activity of several drugs negatively influence cognition in elderly. However, little is known on effect Mild Cognitive Impairment (MCI) Parkinson’s Disease (PD). Methods: Patients with PD belonging to baseline PACOS cohort full pharmacological data, have been included this study. MCI diagnosis was made according MDS level II criteria. defined as patients assuming ≥6 drugs. Anticholinergic burden has calculated using Drug Scale (ADS). Molecules...
Terravecchia, Claudio MD; Mostile, Giovanni MD, PhD; Chisari, Clara Grazia Rascunà, Cristina Terranova, Roberta Cicero, Calogero Edoardo PhD, MSc; Giuliano, Loretta Donzuso, Giulia Sciacca, Giorgia Luca, Antonina Preux, Pierre-Marie Jankovic, Joseph Zappia, Mario Nicoletti, Alessandra MSc Author Information
Abstract Rapid eye movement sleep behavior disorder (RBD) is a common prodromic non-motor symptom of Parkinson’s disease (PD). Only few studies have evaluated the personality RBD patients with conflicting results. Aim study was to evaluate frequency Personality Disorders (PeDs)in RBD. patients, PD and healthy controls (HC) were enrolled. All enrolled subjects underwent full neurological examination. Motor symptoms UPDRS-Motor Examination. PeDs assessed Structured Clinical Interview for...
Background. The aim of this study was to assess verbal reasoning (VR) functioning in patients with Parkinson’s disease (PD) and healthy controls (HCs). Methods. non-demented PD HCs matched by age global cognition were enrolled study. VR assessed the test (VRT), total score, subsets. Results. Eighty-seven (51 men; mean <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1"> <mn>63.8</mn> <mo>±</mo> <mn>7.9</mn> </math> years) 87 (46 id="M2"> <mn>63.7</mn> <mn>8.0</mn> enrolled. At...