A5059033608- Phytochemicals and Antioxidant Activities
- Natural Antidiabetic Agents Studies
- Antioxidant Activity and Oxidative Stress
- Free Radicals and Antioxidants
- Lipid Membrane Structure and Behavior
- Protein Interaction Studies and Fluorescence Analysis
- Plant biochemistry and biosynthesis
- Medicinal plant effects and applications
- Bee Products Chemical Analysis
- Nanoparticle-Based Drug Delivery
- Erythrocyte Function and Pathophysiology
- Biochemical Analysis and Sensing Techniques
- Plant-Derived Bioactive Compounds
- Botanical Research and Chemistry
- Seaweed-derived Bioactive Compounds
- Spectroscopy and Quantum Chemical Studies
- Selenium in Biological Systems
- Synthesis and biological activity
- Molecular Sensors and Ion Detection
- Bioactive Compounds and Antitumor Agents
- Mast cells and histamine
- Transgenic Plants and Applications
- Blood properties and coagulation
- Diverse Scientific Research Studies
- Cytokine Signaling Pathways and Interactions
Wroclaw University of Environmental and Life Sciences
2015-2025
Atherosclerosis is caused by injury to the blood arteries and progressive oxidative stress. Blood cells play an important role in its development; thus, their protection important. Naringenin (N) documented possess a protective action against atherosclerosis, we hypothesize that derivatives, naringin (Nr) dihydrochalcone (Nd), with slightly different structures, similar or better activity. Therefore, this research aimed find mechanism of N, Nr Nd relation erythrocytes, peripheral mononuclear...
The aim of the present research was to determine effect blue honeysuckle fruit and leaf extracts components on physical properties erythrocyte lipid membranes assess their antioxidant properties. HPLC analysis showed that are rich in polyphenol anthocyanins fruits flavonoids leaves. results indicate both have activity protect red blood cell membrane against oxidation induced by UVC irradiation AAPH. do not induce hemolysis slightly increase osmotic resistance erythrocytes. incorporated...
Field horsetail (Equisetum arvense L.) is widely utilized in traditional medicine and a rich source of bioactive compounds such as flavonoids, phenolic acids, silica. This study investigates the protective effect polyphenolic extract from field (HLE) on erythrocytes their cell membranes. The content was determined using HPLC-DAD Folin–Ciocalteu methods. extract’s hemolytic activity, toxicity, antioxidant its impact physical properties lipid membrane were investigated. evaluated isolated...
Compounds contained in fruits and leaves of blackcurrant ( Ribes nigrum L.) are known as agents acting preventively therapeutically on the organism. The HPLC analysis showed they rich polyphenol anthocyanins flavonoids leaves, that have antioxidant activity beneficial for health. aim research was to determine effect fruit leaf extracts physical properties erythrocyte membranes assess their properties. osmotic resistance, shape erythrocytes hemolytic were examined with spectrophotometric...
The aim of the study was to determine in vitro biological activity fruit ethanol extract from Chaenomeles speciosa (Sweet) Nakai (Japanese quince, JQ) and its important constituents (−)-epicatechin (EC) chlorogenic acid (CA). also investigated structural changes phosphatidylcholine (PC) liposomes, dipalmitoylphosphatidylcholine erythrocyte membranes (RBC) induced by extract. It found that effectively inhibits oxidation RBC, 2,2′-azobis (2-amidinopropane) dihydrochloride (AAPH), PC UVB...
The blueberry fruit of the genus Vaccinium, including high blueberry, low and wild bilberry, is consumed for its flavor medicinal properties. purpose experiments was to investigate protective effect mechanism interaction polyphenol extracts with erythrocytes their membranes. content polyphenolic compounds in determined using chromatographic UPLC-ESI-MS method. effects on red blood cell shape changes, hemolysis osmotic resistance were examined. Changes order packing fluidity erythrocyte...
The high antioxidant capacity of chlorogenic acid (CGA) in respect to biological systems is commonly known, though the molecular mechanism underlying that activity not known. aim study was determine at and cell level, particular with regard erythrocyte lipid phase its membrane. effect CGA on erythrocytes membranes studied using microscopic, spectrophotometric electric methods. determined basis changes physical parameters membrane, osmotic resistance shapes erythrocytes, polar head packing...
The purpose of these studies was to determine the effect polyphenols contained in extracts from apple, strawberry and blackcurrant on properties erythrocyte membrane, treated as a model biological membrane. To this end, substances used hemolysis, osmotic resistance shape erythrocytes, packing order hydrophilic region membrane studied. investigation performed with spectrophotometric fluorimetric methods, using optical microscope. hemolytic have shown that do not induce hemolysis at...
The research aimed at determination of the antioxidant properties extracts from leaves and fruits apple tree chlorogenic acid phloridzin, that is compounds contained in held responsible for properties. very good fruit have been known since long ago, though it not yet what action an leaf extract. In order to enquire about effect with respect erythrocyte membrane lipids, ghosts were oxidated presence extracts. was treated as a model cells its example biological membrane. degree lipid oxidation...
The aim of this work is to determine the biological activity ellagitannins rich extracts from leaves raspberry (Rubus idaeus L.) and wild strawberry (Fragaria vesca in relation cells cell membranes. Detailed qualitative quantitative analysis phenolic compounds extract was made using chromatographic methods. Cytotoxic antioxidant activities tested erythrocytes human vascular endothelial (HMEC-1) were determined by fluorimetric spectrophotometric In order establish influence on physical...
Cyanidin and its O-glycosides have many important physiological functions in plants beneficial effects on human health. Their biological activity is not entirely clear depends the structure of molecule, particular, number type sugar substituents. Therefore, this study detailed structure-activity relationship (SARs) anthocyanins/anthocyanidins relation to their interactions with lipid bilayer was determined. On basis antioxidant changes induced by them size Zeta potential vesicles, mobility...
With the aim of contributing to knowledge about their potential therapeutic activity, we determined biological activities cyanidin and its selected O-glycosides in relation erythrocytes (RBCs) human dermal vascular endothelial cells (HMEC-1). Furthermore, on basis changes physical/functional properties cells, structure-activity relationships compounds were determined. Concerning erythrocytes, analyzed antioxidant activity impact RBCs' shape transmembrane potential. The compounds' cytotoxic...
Antioxidant potentials of polyphenolic extracts from leaves trees and fruit bushes The aim the work was to determine antioxidant potential strawberry, blackcurrant apple in relation lipids contained erythrocyte membrane. studies performed have shown that substances used protect membrane against oxidation, clearly reducing level free radicals ghosts suspension. activity studied follows sequence: strawberry > leaves. results research on when confronted with contents polyphenols indicates...
Sea buckthorn and Japanese knotweed are known in many traditional medicine systems to be a great source of bioactive substances. This research aims compare the bioactivity protective effects phenolic extracts leaves from sea roots on erythrocytes. The polyphenol composition extract was analyzed using UPLC-PDA-ESI-MS/MS. extracts’ toxicity impact erythrocytes’ osmotic fragility were measured spectrophotometrically. antioxidant activity determined based inhibition oxidation erythrocytes their...
Silicon dioxide, in the form of nanoparticles, possesses unique physicochemical properties (size, shape, and a large surface to volume ratio). Therefore, it is one most promising materials used biomedicine. In this paper, we compare biological effects both mesoporous silica nanoparticles extracted from Urtica dioica L. pyrogenic material. Both SEM TEM investigations confirmed size range tested was between 6 20 nanometers their amorphous structure. The cytotoxic activity compounds...
1. Akhtar S., Meeran S.M., Katiyar N., S.K., Grape seed proanthocyanidins inhibit the growth of human non-small cell lung cancer xenografts by targeting insulin-like factor binding protein-3, tumor proliferation and angiogenic factors. Clin. Cancer Res., 2009, 15, 821–831. Google Scholar
Abstract The aim of the study was to determine relation between biological activity two homologous series cationic gemini surfactants, which are quaternary ammonium salts, and their structure. measure compounds assumed be effects they exert on membrane erythrocytes, treated as a simple model membrane. In particular, it determined hemolysis osmotic resistance erythrocytes fluidity erythrocyte membrane, packing arrangement polar heads lipids. results have shown that surfactants affect various...