Yu Zhang

ORCID: 0000-0001-8396-4355
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About
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Research Areas
  • Hormonal Regulation and Hypertension
  • Genetics and Neurodevelopmental Disorders
  • Adipose Tissue and Metabolism
  • Lung Cancer Research Studies
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Diagnosis and Treatment
  • Knee injuries and reconstruction techniques
  • Pancreatic and Hepatic Oncology Research
  • Gastric Cancer Management and Outcomes
  • Neonatal and fetal brain pathology
  • Bone fractures and treatments
  • Cancer survivorship and care
  • Orthopedic Surgery and Rehabilitation
  • Galectins and Cancer Biology
  • Cancer Immunotherapy and Biomarkers
  • Radiomics and Machine Learning in Medical Imaging
  • Osteoarthritis Treatment and Mechanisms
  • Total Knee Arthroplasty Outcomes
  • Peptidase Inhibition and Analysis
  • Gastrointestinal Tumor Research and Treatment
  • Esophageal and GI Pathology
  • Cancer Research and Treatments
  • Glycosylation and Glycoproteins Research
  • Delphi Technique in Research
  • Infant Development and Preterm Care

Shaanxi Provincial People's Hospital
2024-2025

Lanzhou University
2017-2024

First Hospital of Lanzhou University
2017-2024

General Hospital of Guangzhou Military Command
2016

Wenzhou Medical University
2016

Duodenal adenocarcinoma (DA) has a high recurrence rate, making the prediction of after surgery critically important. Our objective is to develop machine learning-based model predict postoperative DA. We conducted multicenter, retrospective cohort study in China. 1830 patients with DA who underwent radical between 2012 and 2023 were included. Wrapper methods used select optimal predictors by ten learning learners. Subsequently, these learners utilized for development. The model's performance...

10.1186/s12916-025-03912-7 article EN cc-by-nc-nd BMC Medicine 2025-02-21

The incidence of duodenal adenocarcinoma is increasing, with limited studies on this disease published. This multicenter retrospective study aimed to analyze the clinicopathologic features and identify prognostic factors for postoperative survival.

10.1016/j.surg.2024.08.007 article EN cc-by Surgery 2024-09-10

The prognosis of patients with stage I non-small cell lung cancer (NSCLC) is often uncertain. This study aims to investigate a new prognostic tool classify NSCLC more accurately.CD68 and CD163 macrophages were quantified by immunohistochemical analyses the center tumor invasive margin 339 tumors, which used construct macrophage immunoscore (MI). Cox proportional hazards models determined effects multiple factors on disease-free survival (DFS) overall (OS). One nomogram was developed predict...

10.21037/atm.2020.03.113 article EN Annals of Translational Medicine 2020-04-01

Aim: We investigated the role of GOLPH2 in non-small-cell lung cancer (NSCLC). Methods: analyzed relationship between expression and clinical pathological characteristics patients with NSCLC. The function NSCLC cell lines was also explored through overexpression knockdown studies. Results: positive rate protein tissue higher than that normal tissue. found closely associated unfavorable features an independent predictor prognosis That can promote proliferation invasion cells. Conclusion: is a...

10.2217/bmm-2017-0199 article EN Biomarkers in Medicine 2017-09-07

Objective To investigate the six degrees of freedom (6 DOF ) kinematics anterior cruciate ligament ( ACL deficient knees during gait and to explore clinical significance a novel knee joint stability assessment system (Opti_Knee, Innomotion, Shanghai, China) in comparison with imaging arthroscopic examination. Methods Three subjects diagnosed on basis preoperative MRI CT findings were subjected treadmill analysis. Motion both 6 was measured analyzed an optical measurement system. Arthroscopic...

10.1111/os.12225 article EN Orthopaedic Surgery 2016-02-01

To investigate the role and mechanism of β1,3-N-acetylglucosaminyltransferase-3 gene (B3GNT3) in esophageal cancer (ESCA).The starBase database was used to evaluate expression B3GNT3. B3GNT3 function measured using KYSE-30 KYSE-410 cells squamous cell carcinoma (ESCC) lines. The mRNA levels were detected by quantitative real-time polymerase chain reaction (qRT-PCR). Cell counting kit-8, clone formation assay transwell detect changes proliferation, invasion migration.B3GNT3 higher ESCA...

10.1590/acb380923 article EN PubMed 2023-01-01

Introduction Lung cancer is a common malignancy and major cause of cancer-related deaths worldwide, ranking high in terms morbidity prevalence. Exercise well-established recovery aid for many chronic respiratory conditions lung cancer. However, it difficult to determine the superiority different exercise training modalities using randomised controlled trials (RCTs) or pairwise meta-analyses. Our Bayesian network meta-analysis (NMA) aimed compare impact perioperative on function, capacity,...

10.1136/bmjopen-2021-058788 article EN cc-by-nc BMJ Open 2022-09-01

Background Based on pharmacoeconomics, drug availability and actual treatment, optimal treatment regimens for Chinese non-small-cell lung carcinoma (NSCLC) patients over 70 years old are needed. Methods This multicenter, single-arm pilot trial enrolled with advanced non-squamous NSCLC who refused systemic chemotherapy. Eligible received anlotinib (12 mg/day, d1-14, Q3W) until disease progression, intolerant toxicities, or withdrawal from the study. The primary endpoint was progression-free...

10.3389/fonc.2024.1335009 article EN cc-by Frontiers in Oncology 2024-04-08

Abstract Background For thoracic segment esophageal range, Some think resect double side mediastinal pleura. other never resection has no difference, increased complications. Methods This study used a prospective, randomized controlled method. 213 patients with I-IIIA cancer were randomly divided into two groups. one group of 106 completely removed bilateral Another 107 had the pleura in implementation; Both groups performed lymph node dissection. we observed incidence pleural effusion,...

10.1093/dote/doy089.ps01.119 article EN Diseases of the Esophagus 2018-09-01

10.1016/j.asmart.2016.07.137 article EN cc-by-nc-nd Asia-Pacific Journal of Sports Medicine Arthroscopy Rehabilitation and Technology 2016-10-01

Objective To evaluate the curative effect of arthroscopic treatment for discoid meniscus in different age groups. Methods A total 205 knees 195 patients with were recruited into this retrospective study and divided two groups children (≤16 years old) adults (≥25 old). All underwent treatment. The injury patterns observed intraoperatively knee functions evaluated Lysholm function score perioperatively. Results Excellent outcomes achieved. Under arthroscopy, horizontal tear was a...

10.3760/cma.j.issn.0253-3006.2015.05.005 article EN Zhonghua xiaoerwaike zazhi 2015-05-15
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