Juanjuan Lu

ORCID: 0000-0001-8446-6382
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About
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Research Areas
  • Blood groups and transfusion
  • interferon and immune responses
  • Cardiac Structural Anomalies and Repair
  • DNA Repair Mechanisms
  • Cardiovascular Health and Risk Factors
  • Vitamin D Research Studies
  • Congenital Diaphragmatic Hernia Studies
  • Lipid metabolism and disorders
  • Carcinogens and Genotoxicity Assessment
  • Cancer-related molecular mechanisms research
  • Ubiquitin and proteasome pathways
  • Viral Infections and Outbreaks Research
  • Growth Hormone and Insulin-like Growth Factors
  • Nutrition and Health in Aging
  • X-ray Diffraction in Crystallography
  • Acute Lymphoblastic Leukemia research
  • Histone Deacetylase Inhibitors Research
  • Reproductive System and Pregnancy
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Platelet Disorders and Treatments
  • Influenza Virus Research Studies
  • Blood disorders and treatments
  • Liver Disease Diagnosis and Treatment
  • Respiratory viral infections research
  • Cytokine Signaling Pathways and Interactions

Shanghai Jiao Tong University
2019-2023

Shanghai Ninth People's Hospital
2023

Gansu Provincial Hospital
2014-2020

Second Affiliated Hospital of Zhejiang University
2019

Lanzhou University
2007

First Hospital of Lanzhou University
2007

Cell-intrinsic cGAS-STING–mediated DNA sensing promotes the formation of stem cell–like CD8 + T cells for effective cancer cell therapy.

10.1126/scitranslmed.aay9013 article EN Science Translational Medicine 2020-06-24

Histone deacetylase (HDAC) 2 plays a vital role in modifying histones to mediate inflammatory responses, while HDAC2 itself is commonly regulated by post-translational modifications. Small ubiquitin-related modifier (SUMO), as an important PTM factor, involved the regulation of multiple protein functions. Our previous studies have shown that carbocisteine (S-CMC) reversed cigarette smoke extract (CSE)-induced down-regulation expression/activity thiol/GSH-dependent manner and enhanced...

10.3389/fphar.2019.00166 article EN cc-by Frontiers in Pharmacology 2019-02-26

Abstract Glycoprotein (GP) Ib-IX-V is the second most abundant platelet receptor for thrombin and other ligands crucial hemostasis thrombosis. Its activity involved in adhesion to vascular injury sites thrombin-induced aggregation. GPIb-IX-V a heteromeric complex composed of four subunits, GPIbα, GPIbβ, GPV GPIX, stoichiometric ratio that has been wildly debated. Despite its important physiological roles, overall structure molecular arrangement are not yet fully understood. Here, we purify...

10.1515/hsz-2022-0227 article EN Biological Chemistry 2023-03-21

Introduction: To explore association of excision repair cross-complementing 5 ( ERCC5) genetic polymorphisms with cirrhosis and liver cancer. Methods: A total 365 patients were enrolled, including control group (n = 133), 122), cancer 110). The genotyping ERCC5 rs2016073, rs751402, rs2094258, rs2296147, rs2296148 was measured by using MassARRAY iPLEX technology. Results: There no significant differences in gender drinking among the 3 groups P > .05). both age-group ≤60 >60 subgroup...

10.1177/1533033820943244 article EN cc-by-nc Technology in Cancer Research & Treatment 2020-01-01

Objective To investigate the relationship between trunk fat/lean tissue and metabolic syndrome in over weight or obese premenopausal women. Methods 136 overweight women (BMI≥25.0 kg/m2) was enrolled from our outpatients January 2006 to December 2012. Dual energy x-ray absorptiometry (DEXA) used measure fat, muscle mass, calculated fat content (%TF), leg (%LM), trunk/leg ratio (TMR). Then they were divided into 4 groups, according quartile of %TF, %LM, TMR. Metabolic diagnosis criteria...

10.3760/cma.j.issn.1674-5809.2014.03.006 article EN Chin J Diabetes Mellitus 2014-03-27

Objective To introduce the nursing care of a case Tako-Tsubo cardiomyopathy treated with extracorporeal membrane oxygenation (ECMO) and to improve understanding ECMO. Methods ECMO group combined medical treatment was established treat patients ECMO, special nursing, division labor, close monitoring vital signs related indicators cardiomyopathy, ECMO prevention complications. Results ECMO on board for 30 minutes, blood gas analysis improved, relative indexes were gradually...

10.3760/cma.j.issn.1672-7088.2019.16.015 article EN ˜The œJournal of practical nursing 2019-06-01
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