A5101598766- Mesenchymal stem cell research
- 3D Printing in Biomedical Research
- Bone Tissue Engineering Materials
- Legume Nitrogen Fixing Symbiosis
- Tissue Engineering and Regenerative Medicine
- Neurogenesis and neuroplasticity mechanisms
- Electrochemical sensors and biosensors
- Microfluidic and Bio-sensing Technologies
- Advanced biosensing and bioanalysis techniques
- Advanced Cellulose Research Studies
- Additive Manufacturing and 3D Printing Technologies
- Nerve injury and regeneration
- Diet and metabolism studies
- Electrospun Nanofibers in Biomedical Applications
- Oral microbiology and periodontitis research
- Innovative Microfluidic and Catalytic Techniques Innovation
- Neuroscience and Neural Engineering
- Folate and B Vitamins Research
- Hippo pathway signaling and YAP/TAZ
- Advanced Fiber Laser Technologies
- Advanced Fluorescence Microscopy Techniques
- Bariatric Surgery and Outcomes
- Lignin and Wood Chemistry
- Redox biology and oxidative stress
- Cancer Risks and Factors
Shanghai Ninth People's Hospital
2019-2025
Shanghai Jiao Tong University
2019-2025
Jiangnan University
2020-2024
Tianjin Medical University
2015-2024
Jiangsu University
2016-2024
Northwestern Polytechnical University
2024
Gaochun People's Hospital
2021-2024
Shanghai Sunshine Rehabilitation Center
2023
Second Military Medical University
2014-2023
Chang'an University
2022-2023
The Americas were the last inhabitable continents to be occupied by humans, with a growing multidisciplinary consensus for entry 15-25 thousand years ago (kya) from northeast Asia via former Beringia land bridge [1-4]. Autosomal DNA analyses have dated separation of Native American ancestors Asian gene pool 23 kya or later [5, 6] and mtDNA ∼25 [7], followed isolation ("Beringian Standstill" [8, 9]) 2.4-9 ky then rapid expansion throughout Americas. Here, we present calibrated sequence-based...
Abstract Background Periodontitis is closely associated with chronic systemic diseases. Healthy lifestyle interventions have health-enhancing effects on disorders and periodontitis, but the extent to which healthy combinations are periodontitis unclear. Therefore, this study aimed investigate association between different combinations. Methods 5611 participants were included from National Health Nutrition Examination Survey (NHANES, 2009–2014). Six lifestyles factors defined as fulfilling...
We have investigated human male demographic history using 590 males from 51 populations in the Human Genome Diversity Project - Centre d'Étude du Polymorphisme Humain worldwide panel, typed with 37 Y-chromosomal Single Nucleotide Polymorphisms and 65 Short Tandem Repeats analyzed program Bayesian Analysis of Trees With Internal Node Generation. The general patterns we observe show a gradient oldest population time to most recent common ancestors (TMRCAs) expansion times together largest...
3D printing of composite materials offers an opportunity to combine the desired properties with flexibility additive manufacturing in geometric shape and complexity. In this paper, shear-induced alignment aluminum oxide nanowires during stereolithography was utilized fabricate a nanowire reinforced polymer composite. To align fibers, lateral oscillation mechanism implemented combined wall pattern technique generate shear flow both vertical horizontal directions. A series specimens were...
In this paper, we reported a new approach for particle assembly with acoustic tweezer during three-dimensional (3D) printing the fabrication of embedded conductive wire 3D structures. A hexagon shaped was incorporated Digital Light Processing (DLP) based stereolithography (SLA) printer to pattern lines via aligning and condensing nanoparticles. The effect filler content on electrical resistivity thickness were studied copper, magnetite nanoparticles, carbon nanofiber reinforced nanocomposite...
Neuroinflammation has been identified as another significant pathogenic factor in Alzheimer’s disease following Aβ amyloid deposition and tau protein hyperphosphorylation, activated the central nervous system by glial cells response to injury-related pathogen-related molecular patterns. Moderate cell activity can be neuroprotective; however, excessive activation advances pathology of is accompanied structural changes brain interface, with peripheral immune entering through blood-brain...
A facile method for generation of tumor spheroids in large quantity with controllable size and high uniformity is presented. HCT-116 cells are used as a model cell line. Individual sparsely seeded onto petri-dishes. After few days growth, separated cellular islets formed then detached by dispase while maintaining their sheet shape. These sheets transferred to dispase-doped media under orbital shaking conditions. Assisted the shear flow inhibition cell-to-extracellular matrix junctions...
Wavy-herringbone structured microfluidic devices promote capture and collection of rare tumor cells assisted by magnetic particles.
Abstract The therapeutic efficiency of allogenic/intrinsic neural stem cells (NSCs) after spinal cord injury is severely compromised because the hostile niche at lesion site incurs massive astroglial but not neuronal differentiation NSCs. Although many attempts are made to reconstruct a permissive for nerve regeneration, solely using living cell material build an all‐in‐one, multifunctional, promoting while inhibiting NSCs reported. Here, ectomesenchymal (EMSCs) reported serve as living,...
The inflammatory response in endothelial cells (ECs) leads to an increase vascular permeability through the formation of gaps. However, dynamic nature and external factors involved is still elusive. In this work, we use a biomimetic blood vessel (BBV) microfluidic model measure real-time change EC layer under culture physiologically relevant flow conditions. This platform studies dynamics characterizes when triggered with agent using tracer molecules three different sizes, results are...
Abstract The transplantation of tissue-engineered scaffolds with stem cells is a promising therapeutic approach for bone defect repair. To improve the efficacy this approach, in study, novel biofunctional live bone-like graft was designed and constructed using fibrin scaffold loaded TG2 gene-modified ectomesenchymal (TG2-EMSCs) derived from nasal respiratory mucosa Autocalcification cell-free gel osteogenic medium additional alkaline phosphatase (ALP) differentiation TG2-EMSCs on were...
Roux-en-Y gastric bypass surgery (RYGB) can achieve long-term remission of type 2 diabetes. However, the specific molecular mechanism through which this occurs has remained largely elusive. Bile acid signaling nuclear hormone receptor farnesoid X (FXR) exerts beneficial effects after sleeve gastrectomy (VSG), similar to RYGB. Therefore, we investigated whether FXR is necessary mediate glycemic control RYGB.RYGB or sham was performed in high-fat diet-induced obese FXR-/- (knockout) and FXR+/+...
Abstract Bacterial adaptation is largely shaped by horizontal gene transfer, xenogeneic silencing mediated lineage-specific DNA bridgers (H-NS, Lsr2, MvaT and Rok), various anti-silencing mechanisms. No bridger known for α-proteobacteria, from which mitochondria evolved. By investigating α-proteobacterium Sinorhizobium fredii, a facultative legume microsymbiont, here we report the conserved zinc-finger bearing MucR as novel bridger. Self-association its N-terminal domain (NTD) required...
Taking advantage of the unique CO 2 -switched cellulose solution properties in /DBU/DMSO solvent system, thermal-induced release provides an alternative approach to prepare regenerated materials with IV I crystalline structure.
3D printing has now been recognized as a very practical technique to create structures with milli-/micron-scale resolution. In tissue engineering, particularly, people utilize integrate biodegradable polymers scaffolds. Hydrogel is highly potential material that provides aqua environment and enables nutrition oxygen transportation, all of which are requirements for cells. A combination hydrogel makes the developed platforms more biocompatible, being benign niche cells culture study both in...
Abstract Objectives To assess the magnetic resonance imaging (MRI) in predicting tumour's depth of invasion (DOI) tongue cancer by comparing to pathology and determine cut‐off value MRI‐derived DOI for lymph node metastasis. Patients methods In a retrospective analysis, 156 patients with newly diagnosed were included. Tumour's was compared between MRI measurement Pearson correlation coefficient paired t test. The accuracy pathological DOI. relationship cervical metastasis calculated receiver...