A5101567918- Bariatric Surgery and Outcomes
- Diet and metabolism studies
- Cancer Treatment and Pharmacology
- Diabetes Treatment and Management
- Gastric Cancer Management and Outcomes
- Lung Cancer Treatments and Mutations
- Cardiovascular Disease and Adiposity
- Breast Cancer Treatment Studies
- Body Contouring and Surgery
- HER2/EGFR in Cancer Research
- Advanced Breast Cancer Therapies
- Metabolism, Diabetes, and Cancer
- Colorectal Cancer Treatments and Studies
- Nutrition and Health in Aging
- Cancer Diagnosis and Treatment
- Obstructive Sleep Apnea Research
- Liver Disease Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Oral health in cancer treatment
- Cardiovascular Function and Risk Factors
- Medical Research and Treatments
- Bone health and osteoporosis research
- Neuroendocrine Tumor Research Advances
- Pancreatic and Hepatic Oncology Research
- Thyroid Cancer Diagnosis and Treatment
Shanghai Sixth People's Hospital
2016-2025
Shanghai Jiao Tong University
2016-2025
Nanjing Medical University
2018-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2002-2024
University of South China
2022-2024
Cancer Hospital of Chinese Academy of Medical Sciences
2020-2024
Chengdu Third People's Hospital
2023
Southwest Jiaotong University
2023
Capital Medical University
2015-2023
Beijing Friendship Hospital
2023
Bile acids (BAs) have been suggested as key mediators of the improvements in glucose metabolism after Roux-en-Y gastric bypass (RYGB).The objective study was to test whether individual or a group BAs potential value predict diabetes remission RYGB.A retrospective cohort 38 Chinese obese patients with type 2 mellitus (T2DM) who had undergone RYGB and cross-sectional 327 subjects from Shanghai Obesity Study were involved study.We applied targeted metabolomics approach quantitatively measure 26...
Osteoarthritis (OA) is a common type of degenerative arthropathy. Previous studies have demonstrated that circular RNAs (circRNAs) are involved in the progression OA. This study aimed to investigate role and associated mechanism circ_0075048 The expression was analyzed based on Gene Expression Omnibus dataset GSE178724. Human chondrocytes were stimulated with IL-1β establish an vitro OA model. Bioinformatic analysis performed identify target genes circ_0075048. circ_0075048, miR-663b, LCP1...
To the Editor: Obesity and type 2 diabetes (T2D) present significant health issues in China. Despite generally having lower body mass index (BMI) thresholds than Western populations, Chinese individuals often experience higher rates of central obesity, leading to increased metabolic risks even at BMI levels. The prevalence T2D among adults China is estimated be 11.2%. Traditional treatments, including lifestyle interventions medications, fail achieve sustained weight loss effective glycemic...
Abstract In this study, direct esterification of phytosterols with polyunsaturated fatty acid (PUFA) catalyzed by sodium bisulfate to produce sterol esters PUFA was performed without organic solvent. Considering on both degree (DE) and oxidative stability, response surface methodology (RSM) employed for modeling the phytosterol production obtain a food grade process. The optimal mild reaction conditions were obtained as follows: mass ratio PUFA:phytosterols = 4:1; amount catalyst: 3% raw...
Bariatric surgery has been reported to be an effective treatment for obstructive sleep apnea (OSA). However, this evidence was not enough different populations. Thus, we conducted a follow-up study evaluate the effect of bariatric on OSA in Chinese population with obesity and type 2 diabetes mellitus (T2DM). From May 2011 March 2014, 72 consecutive subjects T2DM were recruited study. Before at least 6 months after laparoscopic Roux-en-Y gastric bypass (LYGB) surgery, all asked undergo...
Mammalian cells respond to various environmental stressors form stress granules (SGs) by arresting cyto-plasmic mRNA, protein translation element, and RNA binding proteins. Virus-induced SGs function in different ways, depending on the species of virus; however, mechanism SG regulation virus replication is not well understood. In this study, Newcastle disease (NDV) triggered stable formation bona fide HeLa through activating kinase R (PKR)/eIF2α pathway. NDV-induced contained classic markers...
Roux-en-Y gastric bypass surgery (RYGB) can achieve long-term remission of type 2 diabetes. However, the specific molecular mechanism through which this occurs has remained largely elusive. Bile acid signaling nuclear hormone receptor farnesoid X (FXR) exerts beneficial effects after sleeve gastrectomy (VSG), similar to RYGB. Therefore, we investigated whether FXR is necessary mediate glycemic control RYGB.RYGB or sham was performed in high-fat diet-induced obese FXR-/- (knockout) and FXR+/+...
Breast cancer has kept increasing since the past decades and incidence rate is highest among all neoplasms nowadays. China, as well other countries, faces severe burden from population with breast cancer. This study aimed to analyze epidemiology clinicopathologic features of in China United States (US).Data hospitalized patients diagnosed primary between 1 January 1999 31 December 2014 Cancer Hospital, Chinese Academy Medical Sciences (CHCAMS) were reviewed. Clinical demographic data...
<b><i>Background:</i></b> Leptin has been shown to stimulate the hypothalamus-pituitary-thyroid (HPT) axis in vivo and vitro. Its role thyroid regulation after weight loss induced by bariatric surgery is still unknown. The aim of this study was evaluate influence leptin on function variation Roux-en-Y gastric bypass (RYGB) euthyroid individuals with obesity type 2 diabetes mellitus (T2DM). <b><i>Methods:</i></b> 65 Chinese T2DM who underwent...
Background: Performing bariatric surgery on patients with a BMI of over 50 kg/m 2 is challenging. This study aimed to explore the status and challenges related perioperative management such in China. Materials methods: A prospective survey was designed investigate greater than or equal undergoing The questionnaire our included general information, preoperative measures, surgical procedures performed, technical details regarding anaesthesia, postoperative measures. response from only one...
Abstract Objective The objective of this study was to determine the role body fat percentage (BFP) changes in diabetes remission (DR) and association between baseline composition its after bariatric surgery. Methods We analyzed 203 patients with type 2 who underwent Roux‐en‐Y gastric bypass. Body measured using a gold‐standard‐derived predictive equation magnetic resonance imaging. were calculated as 100 × (baseline value – follow‐up value)/baseline value. verified results laparoscopic...