A5045974754- Optical Network Technologies
- Advanced Photonic Communication Systems
- Pregnancy and preeclampsia studies
- Photonic and Optical Devices
- Skin and Cellular Biology Research
- Birth, Development, and Health
- Semiconductor Lasers and Optical Devices
- Advanced Optical Network Technologies
- Maternal and fetal healthcare
- Advanced Fiber Laser Technologies
- Extracellular vesicles in disease
- MicroRNA in disease regulation
- Advanced Wireless Communication Techniques
- Respiratory Support and Mechanisms
- Wireless Communication Networks Research
- Reproductive System and Pregnancy
- Ocular Diseases and Behçet’s Syndrome
- Optical Wireless Communication Technologies
- Gestational Diabetes Research and Management
- Blind Source Separation Techniques
- Neuroscience and Neuropharmacology Research
- Ubiquitin and proteasome pathways
- Horticultural and Viticultural Research
- Maternal and Perinatal Health Interventions
- Advanced Wireless Network Optimization
Chongqing Medical University
2014-2025
Dalian Medical University
2025
Second Affiliated Hospital of Chongqing Medical University
2025
Obstetrics and Gynecology Hospital of Fudan University
2012-2025
Northeast Normal University
2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2015-2024
Hunan Normal University
2023-2024
State Grid Corporation of China (China)
2023-2024
Chinese PLA General Hospital
2012-2024
Army Medical University
2023-2024
Intracerebral hemorrhage (ICH), as a type of life-threatening and highly disabled disease, has limited therapeutic approaches. Here, we show that exosomes derived from young healthy human plasma exhibiting typical features could facilitate functional recovery ICH mice. When these are intraventricularly delivered into the brain after ICH, they mainly distribute around hematoma be internalized by neuronal cells. Strikingly, administration markedly enhanced behavioral mice through reducing...
Cerebral hypoperfusion is a pivotal risk factor for vascular dementia (VD), which effective therapy remains inadequate. Persistent inflammatory responses and excessive chemotaxis of microglia/macrophages in the brain may accelerate progression VD. Endocannabinoids are involved neuronal protection against inflammation-induced injury. Cannabinoids acting at cannabinoid receptor 2 (CB2R) can decrease inflammation. Based on identification paeoniflorin (PF) as CB2R agonist, we investigated...
A vast majority of pharmacological compounds and their metabolites are excreted via the urine, within complex structure kidney,the proximal tubules a main target site nephrotoxic compounds. We used model nephrotoxicants mercuric chloride, 2-bromoethylamine hydrobromide, hexachlorobutadiene, mitomycin, amphotericin, puromycin to elucidate time- dose-dependent global gene expression changes associated with tubular toxicity. Male Sprague-Dawley rats were dosed intraperitoneal injection once...
In this paper, we experimentally demonstrate the first 110-Gb/s multi-band superchannel coherent optical orthogonal frequency-division multiplexing based on offset quadrature amplitude modulation (OFDM/OQAM) system. Unlike conventional band-multiplexed OFDM system, no timing or frequency synchronization is required for OFDM/OQAM We further investigate influence of guard band, and find that very trivial band spacing (< 20 MHz) without any sensitivity performance spectral efficiency...
Preeclampsia is associated with developmental delay in infants and an increased risk of various diseases adulthood, including hypertension epilepsy. It has been reported that several organs show retardation functional deficiency offspring preeclamptic rats. However, the changes brains rats remain unknown. Here, we established a preeclampsia-like rat model induced using Nω-nitro-L-arginine methyl ester (L-NAME) to analyze offspring. Body brain weights were decreased L-NAME group at postnatal...
Single-channel 112-Gb/s PAM-4 transmission based on low-cost intensity modulation and direct detection (IM/DD) optics is experimentally demonstrated over 1-km standard single-mode fiber. By employing a digital precompensation, duobinary encode/decoding with signal 7-level training-sequence-aided least mean square (TS-LMS) algorithm, we successfully achieve receiver sensitivity of about -2 dBm 7% overhead HD-FEC. Chirp management applied at the transmitter side to extend reach 1 km for 1500...
Preeclampsia (PE) is a prevalent and severe pregnancy complication that significantly impacts maternal perinatal health. Epidemiological studies animal experiments have demonstrated PE adversely affects the cardiovascular nervous systems of offspring, increasing their risk hypertension renal pathology. However, mechanisms underlying this increased remain unclear. This study utilized an L-NAME-induced preeclampsia mouse model (PELS model) to investigate effects on offspring blood pressure...
In traditional Chinese society, individuals were immersed in a series of life experiences that had profound impact on their worldview and outlook life. This influence persists into the modern era, where natural agricultural living remain significant aspects society. contemporary societal violence is an occasional phenomenon influenced by modernity. It therefore particular importance to explore elements within context cultivation-reading education (agricultural scholarly education) facilitate...
An improved high-order delta-sigma modulator with multi-level quantizer is proposed to enable carrier aggregation of 4G-LTE signals in mobile fronthaul. Different from conventional modulation-based digital fronthaul, a 2-bit employed reduce the quantization noise, which enabling transmission via PAM-4 based IM-DD channel. Moreover, we employ 4th-order high-pass filter (HPF) replace 1st-order HPF modulator, resulting much better noise shaping performance. In experiment, fronthaul 32...
Ichthyoses are clinically and genetically heterogeneous disorders characterized by scaly skin. Despite decades of investigation identifying pathogenic variants in more than 50 genes, clear genotype-phenotype associations have been difficult to establish. To expand the genotypic phenotypic spectra ichthyosis delineate associations. This cohort study recruited an international group individuals with describes characteristic distinguishing features common genotypes, including associations,...
Background/Aims: Pruritus, also known as itch, is a common, unpleasant sensation that can be difficult to treat. Frequently, chronic itch associated with the development of neuropathic pain resulting from nerve injury or insult. Previous studies have shown involvement spinal microglia in pain, but their role pruritus unclear. Methods: For this study, we constructed model mice using repeated applications 2, 4-dinitrofluorobenzene (DNFB) and showed prolonged scratching behavior treated...
The dagger nematode, Xiphinema index, feeds aggressively on grape roots and in the process, vectors grapevine fanleaf virus (GFLV) leading to severe viral disease known as degeneration. Resistance X. index GFLV has been key objective of rootstock breeding programs. A previous study found that resistance derived from Vitis arizonica was largely controlled by a major quantitative trait locus, XiR1 (X. 1), located chromosome 19. presented here develops high-resolution genetic physical maps an...