Shaohua Chen

ORCID: 0000-0001-8783-3977
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Research Areas
  • Enhanced Oil Recovery Techniques
  • Petroleum Processing and Analysis
  • Hydrocarbon exploration and reservoir analysis
  • Advanced Polymer Synthesis and Characterization
  • Hydraulic Fracturing and Reservoir Analysis
  • Surfactants and Colloidal Systems
  • Calcium Carbonate Crystallization and Inhibition
  • Asymmetric Synthesis and Catalysis
  • Synthetic Organic Chemistry Methods
  • Bone Tissue Engineering Materials
  • Photopolymerization techniques and applications
  • Underwater Vehicles and Communication Systems
  • Photochromic and Fluorescence Chemistry
  • Synthesis of Organic Compounds
  • Soil erosion and sediment transport
  • Analytical Chemistry and Sensors
  • Nuclear physics research studies
  • biodegradable polymer synthesis and properties
  • Drilling and Well Engineering
  • Advanced Fiber Optic Sensors
  • Asymmetric Hydrogenation and Catalysis
  • Magnetic confinement fusion research
  • Force Microscopy Techniques and Applications
  • Paleontology and Evolutionary Biology
  • Environmental Chemistry and Analysis

Siddhartha University
2025

Beijing Institute of Technology
2020-2025

Cape Breton University
2025

Wuhan Textile University
2016-2024

Saudi Aramco (United States)
2021-2024

South Subtropical Crops Research Institute
2023

Chinese Academy of Tropical Agricultural Sciences
2023

Hudson Institute
2022

Shanghai Advanced Research Institute
2021

Chinese Academy of Sciences
2005-2021

B-cell acute lymphoblastic leukemia is the most common type of pediatric leukemia. Despite improved remission rates, current treatment regimens for are often associated with adverse effects and central nervous system relapse, necessitating more effective safer agents. Bafilomycin A1 an inhibitor vacuolar H+-ATPase that frequently used at high concentration to block late-phase autophagy. Here, we show bafilomycin a low (1 nM) effectively specifically inhibited killed cells. It targeted both...

10.3324/haematol.2014.113324 article EN cc-by-nc Haematologica 2014-12-15

A simple, efficient, one-pot method has been developed for the synthesis of tetrahydro-4H-chromene derivatives by concurrent reaction aryl aldehydes, active methylene compounds, and 1,3-cyclohexanedins using a catalytic amount lithium bromide in aqueous media. The present approach offers several advantages such as shorter times, good yields, low cost, recycling catalyst, simple workup.

10.1080/00397910903007079 article EN Synthetic Communications 2010-02-02

Abstract Permian hydrothermal activity in the Tarim Basin may have been responsible for invasion of hot brines into Ordovician carbonate reservoirs. Studies undertaken to explain origin and geochemical characteristics diagenetic fluid present during this event although there is no consensus on it. We a genetic model resulting from study δ 13 C, 18 O, 34 S, 87 Sr/ 86 Sr isotope values inclusions ( FI s) fracture‐ vug‐filling calcite, saddle dolomite, fluorite, barite, quartz, anhydrite...

10.1111/gfl.12125 article EN Geofluids 2014-11-24

The synergistic effects of surfactant–polymer (SP) flooding under high-temperature and high-salinity (HTHS) conditions were investigated for a hydrophobically associating polyacrylamide (HAPAM) mixed with different types surfactants. hydrophobic group the polymer is positively charged. All surfactants contain 12 carbons at chain. list included cationic surfactant (DTAB: dodecyl trimethylammonium bromide), an anionic (SDS: sodium sulfate) nonionic (DDG: glucopyranoside). physical properties...

10.1021/acs.energyfuels.1c01034 article EN Energy & Fuels 2021-06-04

In response to growing concerns about environmental sustainability and waste management, the exploration of alternative construction materials has gained prominence. One such is common effluent treatment plant (CETP) sludge, a byproduct industrial wastewater that poses significant challenges. This study aims evaluate feasibility substituting conventional fine aggregate with CETP sludge in concrete mixtures, addressing disposal issues enhancing construction. The research investigates...

10.2139/ssrn.5016388 article EN SSRN Electronic Journal 2025-01-01

Abstract Although the mechanical mechanisms of staggered biological composites are widely investigated, each existing model has its own application scope. In order to comprehensively characterize properties composite with arbitrary soft phase content, a generalized shear lag is established, in which may simultaneously bear tension and loads. A novel approach considering as virtual layered composed sub-soft sub-hard phases developed. The zero thickness undergoes tensile load, while endures...

10.1115/1.4067598 article EN Journal of Applied Mechanics 2025-01-09

Abstract In the present paper, we study well-posedness of solution to initial boundary value problem for damped Kirchhoff-type wave equation with fractional Laplacian. First, existence and uniqueness local are established by Banach fixed point theorem. Then, global finite time blowup derived at subcritical critical energy levels. Finally, upper bound lower estimate given arbitrarily positive level.

10.1515/ans-2023-0172 article EN cc-by-nc-nd Advanced Nonlinear Studies 2025-03-13

Abstract Surfactant-polymer (SP) flooding has been considered as an important and high-efficient method to displace the residual oil trapped inside formation rock after initial water flooding. Due molecular interactions, some SP formulations exhibit a synergistic effect further enhance their performance in displacement. Current study aims at investigating synergy chemical using containing different types of surfactants increase sweeping efficiency displacement efficiency. Among comprising...

10.2118/224240-ms article EN SPE International Conference on Oilfield Chemistry 2025-04-02

Abstract A CO2-modified non-ionic surfactant alkyl polyglycoside (APG) was synthesized for consuming CO2 to reduce carbon footprint and improving the performance of APG surfactant. Commercially available used as a raw material reacted with in solvent mixture containing dimethyl sulfoxide (DMSO) superbase 1,8-diazabicyclo [5.4.0] undec-7-ene (DBU) prepare (CO2-APG) under mild synthesis conditions including low temperature (50-60°C) pressure (2-3 bar). The reaction not reversible external...

10.2118/224239-ms article EN SPE International Conference on Oilfield Chemistry 2025-04-02

A series of poly(ethylene oxide)s labeled at both ends with pyrene, (PEO(X)-Py(2), where X represents the number average molecular weight (M(n)) PEO chains and equals 2, 5, 10, 16.5 K) was prepared together one-pyrene-monolabeled (PEO(2K)-Py). The process end-to-end cyclization (EEC) investigated by monitoring intramolecular excimer formation in seven organic solvents viscosities (η) ranging from 0.32 to 1.92 mPa·s. steady-state fluorescence spectra showed that PEO(X)-Py(2) decreased...

10.1021/jp109528h article EN The Journal of Physical Chemistry B 2011-03-15

A majority of carbonate reservoirs are preferably oil-wet or intermediate wet. Spontaneous imbibition represents an important mechanism to enhance oil production. Targeting reservoir with high temperature and salinity, several surfactant formulations were investigated improve production by imbibition, focusing on the capacity in interfacial tension (IFT) reduction partitioning water phases addition dominant wettability alteration effect. Oil potentials using different surfactants evaluated...

10.1016/j.jciso.2022.100045 article EN cc-by-nc-nd JCIS Open 2022-01-22

A novel water-soluble viscosity reducer system based on polycyclic aromatic hydrocarbon (PAH) was designed and synthesized for heavy oil reduction enhanced production by displacement. This reducing agent (VRA) is composed of three components: the first one a polyacrylamide (PAM) copolymer that contains hydrophobic pyrene groups, namely, P(Am-co-Py) (PAP); second nonionic surfactant, n-dodecyl β-d-glucopyranoside (DDG); third component partially hydrolyzed PAM terpolymer bears naphthalene...

10.1021/acs.energyfuels.3c02090 article EN Energy & Fuels 2023-08-02

Previous analyses have reported that the human monocytic cell line THP1 can be differentiated into cells with macrophage-like characteristics by phorbol 12-myristate 13-acetate (PMA). However, little is known about mechanism responsible for regulating this differentiation process. Here, we performed high-throughput RNA-Seq analysis to investigate genes differently expressed in treated and without PMA examined those may PMA-induced of monocytes macrophages. We found 3,000 differentially after...

10.1007/s11427-015-4967-4 article EN cc-by Science China Life Sciences 2015-11-18

$\ensuremath{\gamma}$-ray transitions between low-spin states of the neutron-rich $^{84,86,88}\mathrm{Ge}$ were measured by means in-flight spectroscopy at 270 MeV/u. Excited ${6}_{1}^{+},\phantom{\rule{0.16em}{0ex}}{4}_{1,2}^{+}$, and ${2}_{1,2}^{+}$ $^{84,86}\mathrm{Ge}$ ${4}_{1}^{+}$ $^{88}\mathrm{Ge}$ observed. Furthermore, a candidate for ${3}_{1}^{+}$ state $^{86}\mathrm{Ge}$ was identified. This plays key role in discussion ground-state triaxiality $^{86}\mathrm{Ge}$, along with other...

10.1103/physrevc.96.011301 article EN Physical review. C 2017-07-05

Summary Nuclear magnetic resonance (NMR) was used to investigate the exposure between carbon dioxide (CO2) and sandstone matrix with a permeability of 0.218 md porosity 9.5% at 40°C 12 MPa (immiscible condition). Minimum miscibility pressure (MMP) oil CO2 17.8 MPa, determined by slimtube test 40°C. The process included first, second, third, fourth experiments. Before each experiment started, there CO2-injection stage injection under constant rate keep fresh (concentration is 100% in gas...

10.2118/179554-pa article EN SPE Journal 2017-11-02

Abstract An efficient organocatalytic method for the asymmetric preparation of benzopyran‐ and benzofuran‐fused polycyclic acetals is described first time. This useful approach includes an interesting tunable Michael–acetalization nitrostyrenes or α‐aromatization–acetalization quinones. Under mild conditions, simple cyclic hemiacetals could be stereoselectively converted into four different types polyheterocycles that serve as scaffolds a number bioactive natural products. magnified image

10.1002/adsc.201601335 article EN Advanced Synthesis & Catalysis 2017-03-25

The formation of the large hydro-fluctuation belt at altitude 145–175 m, following construction Three Gorges Dam, developed from terrestrial system in reservoir. This research mainly concerned effects resultant reverse seasonal flooding on soil texture. Four field experimental plots were designed with sample belts and quadrats head, middle, tail sections reservoir area. Stratified samples collected, followed by analysis structure grain size collected samples. significantly changes texture...

10.1007/s11368-017-1725-1 article EN cc-by Journal of Soils and Sediments 2017-05-20

Abstract Photo‐differential scanning calorimetry (photo‐DSC) and UV‐visible spectrometry were used to investigate the photocuring kinetics of visible light initiated cationic photopolymerization triethyleneglycol divinyl ether with a diphenyl iodonium salt three photosensitizers, 1‐chloro‐4‐propoxy‐9H‐thioxanthen‐9‐one (CPTXO), acridine orange (AO), camphorquinone (CQ). Although all photosensitizers effective in causing photopolymerization, CPTXO AO photo‐reacted during irradiation; whereas...

10.1002/pola.23599 article EN Journal of Polymer Science Part A Polymer Chemistry 2009-09-10

Summary. A biosensor based on imaging ellipsometry (BIE) has been developed and validated in 169 patients for detecting five markers of hepatitis B virus (HBV) infection. The methodology established to pave the way clinical diagnosis, including ligand screening, determination sensitivity, set‐up cut‐off values (CoVs) comparison with other methods. matrix assay method was screening. CoVs HBV were derived help receiver operating characteristic curves. Enzyme‐linked immunosorbent (ELISA)...

10.1111/j.1365-2893.2009.01123.x article EN Journal of Viral Hepatitis 2009-03-26
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