A5055034503- Animal Nutrition and Physiology
- Animal Genetics and Reproduction
- Meat and Animal Product Quality
- Aquaculture Nutrition and Growth
- Reproductive biology and impacts on aquatic species
- Sperm and Testicular Function
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Animal Behavior and Welfare Studies
- Effects of Environmental Stressors on Livestock
- Identification and Quantification in Food
- Epigenetics and DNA Methylation
- Genetic and phenotypic traits in livestock
- Protein Hydrolysis and Bioactive Peptides
- Calcium Carbonate Crystallization and Inhibition
- Phytase and its Applications
- Reproductive Biology and Fertility
- Livestock and Poultry Management
- Coccidia and coccidiosis research
- Proteins in Food Systems
- Parasitic Infections and Diagnostics
- Rabbits: Nutrition, Reproduction, Health
- Enzyme Production and Characterization
- Selenium in Biological Systems
- Infant Nutrition and Health
- Congenital heart defects research
Fish Physiology and Genomics Institute
2021-2024
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2020-2024
Biologie des Oiseaux et Aviculture
2012-2024
Université de Tours
2018-2020
Centre Val de Loire
2020
Infectiologie Animale et Santé Publique
2019
Institut National de la Recherche Agronomique
2014-2015
Physiologie de la Reproduction et des Comportements
2015
The main objective of ViSEAGO package is to carry out a data mining biological functions and establish links between genes involved in the study. We developed R facilitate functional Gene Ontology (GO) analysis complex experimental design with multiple comparisons interest. It allows study large-scale datasets together visualize GO profiles capture knowledge. acronym stands for three major concepts analysis: Visualization, Semantic similarity Enrichment Analysis Ontology. provides access...
The chicken eggshell is a natural mechanical barrier to protect egg components from physical damage and microbial penetration. Its integrity strength critical for the development of embryo or ensure consumers table free pathogens. This study compared global gene expression in laying hen uterus presence absence shell calcification order characterize products involved supply minerals / biomineralization process.Microarrays were used identify repertoire 302 over-expressed genes during...
Meat type chickens have limited capacities to cope with high environmental temperatures, this sometimes leading mortality on farms and subsequent economic losses. A strategy alleviate problem is enhance adaptive face heat exposure using thermal manipulation (TM) during embryogenesis. This was shown improve thermotolerance their life span. The aim of study determine the effects TM (39.5 °C, 12 h/24 vs 37.8 °C from d7 d16 embryogenesis) a challenge (32 for 5 h) applied d34 gene expression in...
The avian eggshell membranes surround the egg white and provide a structural foundation for calcification of which is essential reproduction; moreover, it also natural biomaterial with many potential industrial biomedical applications. Due to insoluble stable nature membrane fibres, their formation protein constituents remain poorly characterized. purpose this study was identify genes encoding proteins, particularly those responsible its features, by analyzing transcriptome isthmus segment...
To meet the high calcium (Ca) demand during eggshell biomineralization (2g of Ca per egg), laying hens develop specific metabolic regulations to maintain homeostasis. The intake Ca, its solubilization, and absorption capacity are enhanced at sexual maturity (SM). A better knowledge intestinal transporters involved in their variations this stage could indicate new nutritional strategies enhance digestive utilization. Transcellular pathway major player calbindin-D 28K (CALB1) mediate a...
Abstract The broiler industry is facing an increasing prevalence of breast myopathies, such as white striping (WS) and wooden (WB), the precise aetiology these occurrences remains poorly understood. To progress our understanding structural changes molecular pathways involved in a transcriptomic analysis was performed using 8 × 60 K Agilent chicken microarray histological study. study used pectoralis major muscles from three groups: slow-growing animals (n = 8), fast-growing visually free...
Changes in gene activity through epigenetic alterations induced by early environmental challenges during embryogenesis are known to impact the phenotype, health, and disease risk of animals. Learning how cues translate into persisting memory may open new doors improve robustness resilience developing It has previously been shown that heat tolerance male broiler chickens was improved cyclically elevating egg incubation temperature. The embryonic thermal manipulation enhanced expression...
To better appreciate the dynamics of yolk proteins during embryonic development, we analyzed protein quantitative changes occurring in plasma at day lay and after 12 days incubation, by comparing unfertilized fertilized chicken eggs. Of 127 identified proteins, 69 showed relative abundance differences among conditions. Alpha-fetoprotein two uncharacterized (F1NHB8 F1NMM2) were for first time egg. After five (vitronectin, α-fetoprotein, similar to thrombin, apolipoprotein B, apovitellenin-1)...
In many amniotes, the amniotic fluid is depicted as a dynamic milieu that participates in protection of embryo (cushioning, hydration, and immunity). However, birds, protein profile remains unexplored, even though its proteomic signature predicted to differ compared with humans. fact, unlike humans, chicken does not collect excretory products composition strikingly changes at mid-development because massive inflow egg white proteins, which are thereafter swallowed by support growth. Using...
Spermatozoa are the cells that most commonly used for cryopreservation of valuable genetic resources in aquaculture. It is known fish spermatozoa transmit to embryo not only their but also epigenetic profile, especially DNA methylation. Therefore, any alteration methylation profile induces risk transmitting alterations offspring. The aim this study was assess effect on rainbow trout spermatozoa. To trigger variable cellular response after freezing-thawing, from mature males were...
Coccidia are obligate intracellular protozoan parasites responsible for human and veterinary diseases. Eimeria tenella, the aetiologic agent of caecal coccidiosis, is a major pathogen chickens. In Toxoplasma gondii, some kinases from rhoptry compartment (ROP) key virulence factors. ROP hijack modulate many cellular functions pathways, allowing T. gondii survival development. E. tenella's kinome comprises 28 putative members kinase family; most them predicted, as pseudokinases their have...
Abstract Background At sexual maturity, the liver of laying hens undergoes many metabolic changes to support vitellogenesis. In published transcriptomic approaches, hundreds genes were reported be overexpressed in and functional gene annotation using ontology tools have essentially revealed an enrichment lipid protein metabolisms. We reanalyzed some data from a previously article comparing 38-week old versus 10-week give more integrative view functions stimulated at maturity move beyond...
Abstract Uterine fluid is an aqueous milieu to which sperm are exposed during their storage and ascent. In this study, a bottom‐up proteomic strategy bioinformatic analysis of hen uterine was performed improve the understanding its potential role in survival mechanisms. The data were submitted ProteomeXchange. Among 913 proteins identified, 160 known be secreted 640 referenced exosomes databases. We isolated from avian fluid, analyzed them using electron microscopy, targeted several markers...
Glyphosate (Gly) is the active molecule of non-selective herbicides used in conventional agriculture. Some evidence shows that exposure to Glyphosate-Based Herbicides (GBH) can affect both male and female fertility animal models. However, few data exist on birds be easily exposed through their cereal-based diet. To our knowledge, there are no current studies effects chronic dietary GBH potential reversibility embryo development chickens. In protocol, hens (32 weeks-old) were (47 mg...
Overfed hens selected for their rapid growth become fatter and develop reproductive disorders. Herein, we aimed to demonstrate that food restriction leading a weight reduction and/or supplementation with fish oil may be effective in preventing disorders through the regulation of adipokine expression broiler hens. This study included four groups restricted (Rt) or ad libitum (Ad, feeding at rate 1.7 times greater than Rt hens) supplemented unsupplemented (1%). The diet significantly increased...
In broiler hens, the genetic selection increased susceptibility to metabolic disorders and reproductive dysfunctions. human ovarian cells, grape seed extracts (GSE) improved steroid production. Here, we investigated effects of a GSE dietary supplementation on egg production quality, fertility parameters, Reactive Oxygen Species (ROS) content in yolk associated plasma adipokines hens. For this, designed two vivo experiments, first one included three groups hens: A (control), B C (supplemented...
Chicken eggshell is the protective barrier of egg. It a biomineral composed 95% calcium carbonate on calcitic form and 3.5% organic matrix proteins. Mineralization process occurs in uterus into uterine fluid. This acellular fluid contains ions proteins precursors which are interacting with mineral phase control crystal growth, structure mechanical properties. We performed proteomic approach identified 308 Gene Ontology terms enrichments were determined to investigate their potential...
In poultry, in vitro propagated primordial germ cells (PGCs) represent an important tool for the cryopreservation of avian genetic resources. However, several studies have highlighted sexual differences exhibited by PGCs during propagation, which may compromise their reproductive capacities. To understand this phenomenon, we compared proteome pregonadal migratory male (ZZ) and female (ZW) chicken quantitative proteomic analysis using a GeLC-MS/MS strategy. Many proteins were found to be...