A5059236519- Chromosomal and Genetic Variations
- Genomics and Phylogenetic Studies
- Genetic Mapping and Diversity in Plants and Animals
- RNA and protein synthesis mechanisms
- Animal Genetics and Reproduction
- Animal Nutrition and Physiology
- Plant Disease Resistance and Genetics
- Nerve Injury and Rehabilitation
- Plant Virus Research Studies
- Genomics and Chromatin Dynamics
- Bacteriophages and microbial interactions
- RNA Research and Splicing
- Genetic and phenotypic traits in livestock
- Genetics, Bioinformatics, and Biomedical Research
- Spinal Cord Injury Research
- Plant tissue culture and regeneration
- CRISPR and Genetic Engineering
- Reproductive Biology and Fertility
- Plant and Fungal Interactions Research
- Insect Utilization and Effects
- Genetics, Aging, and Longevity in Model Organisms
- Protist diversity and phylogeny
- Neurobiology and Insect Physiology Research
- GABA and Rice Research
- Cassava research and cyanide
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2021-2025
Université de Tours
2010-2025
Physiologie de la Reproduction et des Comportements
2014-2024
Centre National de la Recherche Scientifique
2014-2024
Biologie des Oiseaux et Aviculture
2024
Institut Français du Cheval et de l'Équitation
2024
Pharmac
2021
Centre Val de Loire
2014-2019
Université de Lille
1986-2016
Genoscope
2014
The green lineage is reportedly 1,500 million years old, evolving shortly after the endosymbiosis event that gave rise to early photosynthetic eukaryotes. In this study, we unveil complete genome sequence of an ancient member lineage, unicellular alga Ostreococcus tauri (Prasinophyceae). This cosmopolitan marine primary producer world's smallest free-living eukaryote known date. Features likely reflecting optimization environmentally relevant pathways, including resource acquisition, unusual...
Picoeukaryotes are a taxonomically diverse group of organisms less than 2 micrometers in diameter. Photosynthetic marine picoeukaryotes the genus Micromonas thrive ecosystems ranging from tropical to polar and could serve as sentinel for biogeochemical fluxes modern oceans during climate change. These broadly distributed primary producers belong an anciently diverged sister clade land plants. Although isolates have high 18S ribosomal RNA gene identity, we found that genomes two shared only...
Retrotransposons are the main components of eukaryotic genomes, representing up to 80% some large plant genomes. These mobile elements transpose via a “copy and paste” mechanism, thus increasing their copy number while active. Their accumulation is now accepted as factor genome size increase in higher eukaryotes, besides polyploidy. However, dynamics this process poorly understood. In study, we show that Oryza australiensis , wild relative Asian cultivated rice O. sativa has undergone recent...
Abstract The grass family comprises the most important cereal crops and is a good system for studying, with comparative genomics, mechanisms of evolution, speciation, domestication. Here, we identified characterized evolution shared duplications in rice (Oryza sativa) wheat (Triticum aestivum) genomes by comparing 42,654 gene sequences 6426 mapped ESTs using improved sequence alignment criteria statistical analysis. Intraspecific comparisons 29 interchromosomal covering 72% genome 10...
The Rice Annotation Project Database (RAP-DB) was created to provide the genome sequence assembly of International Genome Sequencing (IRGSP), manually curated annotation sequence, and other genomics information that could be useful for comprehensive understanding rice biology. Since last publication RAP-DB, IRGSP has been revised reassembled. In addition, a large number rice-expressed tags have released, functional resources produced worldwide. Thus, we thoroughly updated our by manual...
Summary A library of 29 482 T‐DNA enhancer trap lines has been generated in rice cv. Nipponbare. The regions flanking the left border from first 12 707 primary transformants were systematically isolated by adapter anchor PCR and sequenced. survey 7480 genomic sequences larger than 30 bp (average length 250 bp), representing 56.4% total readable matching bacterial artificial chromosome/phage chromosome (BAC/PAC) assembled pseudomolecules allowed assigning 6645 (88.8%) insertion sites to at...
Nuclear detection, segmentation and morphometric profiling are essential in helping us further understand the relationship between histology patient outcome. To drive innovation this area, we setup a community-wide challenge using largest available dataset of its kind to assess nuclear cellular composition. Our challenge, named CoNIC, stimulated development reproducible algorithms for recognition with real-time result inspection on public leaderboards. We conducted an extensive...
Summary Long terminal repeat (LTR) retrotransposons constitute a significant portion of most eukaryote genomes and can dramatically change genome size organization. Although LTR retrotransposon content variation is well documented, the dynamics genomic flux caused by their activity are poorly understood on an evolutionary time scale. This primarily because lack experimental system composed closely related species whose divergence times within limits ability to detect ancestrally...
Cost effective next generation sequencing technologies now enable the production of genomic datasets for many novel planktonic eukaryotes, representing an understudied reservoir genetic diversity. O. tauri is smallest free-living photosynthetic eukaryote known to date, a coccoid green alga that was first isolated in 1995 lagoon by Mediterranean sea. Its simple features, ease culture and its 13 Mb haploid nuclear genome have promoted this microalga as new model organism cell biology. Here, we...
Transposable elements (TEs) are mobile entities that densely populate most eukaryotic genomes and contribute to both their structural functional dynamics. However, TE-related sequences in plant animal correspond inactive, degenerated elements, due the combined effect of silencing pathways elimination through deletions. One major difficulties fully characterizing molecular basis genetic diversity a given species lies establishing its genome-wide transpositional activity. Here, we provide an...
Summary A unigene set of 1411 contigs was constructed from 2629 redundant maize expressed sequence tags (ESTs) mapped on the maizeDB genetic map. Rice orthologous sequences were identified by blast alignment against rice genomic sequence. total 1046 (74%) associated with their corresponding homologues in genome and 656 (47%) defined as potential relationships. One hundred seventeen (8%) EST to two distinct loci map, reflecting tetraploid nature genome. Among 492 mono‐locus contigs, 344 (484...
Summary Horizontal gene transfer, defined as the transmission of genetic material between reproductively isolated species, has been considered for a long time to be rare phenomenon. Most well‐documented cases horizontal transfer have described in prokaryotes or animals and they often involve transposable elements. The most abundant class elements plant genomes are terminal repeat (LTR) retrotransposons. Because their propensity increase copy number while active, LTR retrotransposons can...
Abstract Background Horizontal transfers (HTs) refer to the transmission of genetic material between phylogenetically distant species. Although most cases HTs described so far concern genes, there is increasing evidence that some involve transposable elements (TEs) in Eukaryotes. The availability full genome sequence two cereal species, ( i.e . rice and Sorghum ), as well partial maize, provides opportunity carry out genome-wide searches for TE-HTs Poaceae Results We have identified an...
Transposable elements are ubiquitous components of plant genomes. When active, these mobile can induce changes in the genome at both structural and functional levels. Availability complete sequence for several model species provides opportunity to study TEs plants an unprecedented scale. In case rice, annotation genomic variety Nipponbare has revealed that TE-related sequences form more than 25% its genome. However, most found inactive, either because alterations or they target various...
Changes in gene activity through epigenetic alterations induced by early environmental challenges during embryogenesis are known to impact the phenotype, health, and disease risk of animals. Learning how cues translate into persisting memory may open new doors improve robustness resilience developing It has previously been shown that heat tolerance male broiler chickens was improved cyclically elevating egg incubation temperature. The embryonic thermal manipulation enhanced expression...
<title>Abstract</title> Autism spectrum disorders (ASD) are complex, polygenic and heterogenous neurodevelopmental conditions, imposing a substantial economic burden. ASD genetics is influenced by the environment, specifically social experience during critical period. Despite efficacy of early behavioral interventions targeting specific behaviors in some autistic children, there currently no sustainable treatment for two core symptoms: deficits interaction communication, stereotyped or...
Abstract In this work, we investigate whether the construction of signaling pathways during evolution follows a deterministic law through study eventual link between age appearance in tree life and position pathway genes involved these pathways. We use 47 human described Kyoto Encyclopedia Genes Genomes orthologs 315 animal species plus yeast taxon, representing 15 large clades. Many appear on two key branches: those last common ancestor Opisthokonta Metazoa Deuterostomia Chordata. look for...
Long terminal repeat (LTR)-retrotransposons comprise a significant portion of the rice genome. Their complete characterization is thus necessary if sequenced genome to be annotated correctly. In addition, because LTR-retrotransposons can influence expression neighboring genes, identification these elements in essential order study their putative functional interactions with plant genes. The aims database are (i) Assemble comprehensive dataset that includes not only abundant elements, but...
Dans un article paru il y a dix-neuf ans, j'ai tenté de prouver que le prétoire où Pilate condamna Jésus doit être cherché dans l'ancien palais d'Hérode, à la limite occidentale l'antique Jérusalem, près l'actuelle Porte Jaffa, plutôt forteresse l'Antonia, sise l'angle nord-ouest l'enceinte du Temple, aujourd'hui Haram esh-Sherif. Ma démonstration s'appuyait sur les témoignages littéraires. l'article simultané défendait position contraire, mon vénéré maître P. Vincent déclarait “le meilleur,...
Abstract Background The plant miRNAs represent an important class of endogenous small RNAs that guide cleavage mRNA target or repress its translation to control development and adaptation stresses. MiRNAs are nuclear-encoded genes transcribed by RNA polymerase II, producing a primary precursor is subsequently processed DCL1 RNase III Dicer-like protein. In rice hundreds have been described predicted, but little known on their precursors which criteria distinguish them from siRNAs. Here we...
Transposable elements are driving forces for establishing genetic innovations such as transcriptional regulatory networks in eukaryotic genomes. Here, we describe a silencer situated the last 300 bp of Mos1 transposase open reading frame (ORF) which functions vertebrate and arthropod cells. Functional silencers also found at similar locations within three other animal mariner elements, i.e. IS630-Tc1-mariner (ITm) DD34D Himar1, Hsmar1 Mcmar1. These able to impact promoters monitoring strong,...