A5068254303- Sarcoma Diagnosis and Treatment
- Gastrointestinal Tumor Research and Treatment
- Gastric Cancer Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neurofibromatosis and Schwannoma Cases
- Soft tissue tumor case studies
- Pancreatic and Hepatic Oncology Research
- Immunotherapy and Immune Responses
- Colorectal and Anal Carcinomas
- Cardiac tumors and thrombi
- Soft tissue tumors and treatment
- Virus-based gene therapy research
- Radiomics and Machine Learning in Medical Imaging
- Gastrointestinal disorders and treatments
- Cancer Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Surgical site infection prevention
- CAR-T cell therapy research
- Hernia repair and management
- Musculoskeletal synovial abnormalities and treatments
- Neuroblastoma Research and Treatments
- Gallbladder and Bile Duct Disorders
- Viral-associated cancers and disorders
- Inflammatory Biomarkers in Disease Prognosis
- Intestinal Malrotation and Obstruction Disorders
IRCCS Humanitas Research Hospital
2021-2025
Humanitas University
2018-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2022
Institut Curie
2021
American Association for the Surgery of Trauma
2021
University of Turin
2021
Azienda Ospedaliero Universitaria Ospedali Riuniti
2021
Azienda Socio Sanitaria Territoriale Lariana
2021
European Neuroendocrine Tumor Society
2018
Background and Objectives Several inflammation markers were found to have a prognostic value in cancer. We investigated the significance of preoperative white cell ratios determining gastrointestinal stromal tumors (GISTs) outcome. Methods Clinicopathological features patients who underwent surgery for GIST reviewed. The following peripheral blood calculated: neutrophil‐lymphocyte ratio (NLR), monocyte‐lymphocyte (MLR), platelet‐lymphocyte (PLR), neutrophil‐white (NWR), lymphocyte‐white...
ABSTRACT Introduction Complete surgical resection is the mainstay of treatment for retroperitoneal sarcomas (RPS). For primary well‐differentiated liposarcomas and dedifferentiated liposarcomas, aggressive en‐bloc adjacent organs crucial local control. Diaphragmatic may be necessary in left‐sided RPS cases. While closure defects usually possible, large require alternative methods such as prosthetic reconstruction. Methods We developed an innovative technique reconstructing diaphragmatic...
Preoperative identification of the cause adhesive small bowel obstruction (ASBO) is crucial for decision making. Some computed tomography (CT) findings can be indicative single bands or matted adhesions. Our aim was to build a predictive model based on CT data discriminate ASBO due band adhesions.A retrospective center study conducted, covering all consecutive patients with preoperative scan, undergoing urgent surgery between January 1, 2005, and December 31, 2017. scans were blindly...
<sec> <title>BACKGROUND</title> Gastrointestinal stromal tumors (GISTs) present a complex clinical landscape, where precise preoperative risk assessment plays pivotal role in guiding therapeutic decisions. Conventional methods for evaluating mitotic count, such as biopsy-based assessments, encounter challenges stemming from tumor heterogeneity and sampling biases, thereby underscoring the urgent need innovative approaches to enhance prognostic accuracy. </sec> <title>OBJECTIVE</title> The...
<title>Abstract</title> Background: The antigen processing machinery (APM) plays a critical role in generating tumor-specific antigens that can be recognized and targeted by the immune system. status of APM sarcomas is not well characterized. Methods: We investigated 126 patients with 8 types bone soft tissue sarcoma operated between 2001-2021. Tissue microarrays mapped 11 specific areas each case. presence/absence protein was determined through immunohistochemistry. Bayesian networks were...
Background Gastrointestinal stromal tumors (GISTs) present a complex clinical landscape, where precise preoperative risk assessment plays pivotal role in guiding therapeutic decisions. Conventional methods for evaluating mitotic count, such as biopsy-based assessments, encounter challenges stemming from tumor heterogeneity and sampling biases, thereby underscoring the urgent need innovative approaches to enhance prognostic accuracy. Objective The primary objective of this study was develop...
Regorafenib is a tyrosine kinase inhibitor (TKI) approved in metastatic gastrointestinal stromal tumor (GIST), colorectal cancer, and hepatocarcinoma. Anyway, the toxicity profile of standard schedule associated with poor compliance high rate discontinuation. For this reason, there growing need for personalized emerging from scientific community.The aim case series was to describe experience our sarcoma referral center continuous administration as an alternative regimen treat GIST...