A5019426036- Cutaneous Melanoma Detection and Management
- Cancer and Skin Lesions
- Genetic and rare skin diseases.
- Melanoma and MAPK Pathways
- Cancer Genomics and Diagnostics
- melanin and skin pigmentation
- Cutaneous lymphoproliferative disorders research
- Hedgehog Signaling Pathway Studies
- Nail Diseases and Treatments
- Cardiovascular Function and Risk Factors
- CAR-T cell therapy research
- BRCA gene mutations in cancer
- Nonmelanoma Skin Cancer Studies
- Heart Failure Treatment and Management
- Ear and Head Tumors
- Diagnosis and Treatment of Venous Diseases
- Lung Cancer Treatments and Mutations
- Cell Image Analysis Techniques
- Dermatology and Skin Diseases
- CRISPR and Genetic Engineering
- Skin Diseases and Diabetes
- Diabetic Foot Ulcer Assessment and Management
- Immunotherapy and Immune Responses
- Advanced Antenna and Metasurface Technologies
- Health Systems, Economic Evaluations, Quality of Life
Hospital São Lucas da PUCRS
2023
Pontifícia Universidade Católica do Rio Grande do Sul
2016-2023
Universidade Federal de Ciências da Saúde de Porto Alegre
2009-2017
San Gallicano Hospital
2010
Technical University of Munich
2008
Summary Objective: Investigation of the efficacy ultraviolet (UV) A1 phototherapy on atopic eczema, scleroderma, granuloma annulare, urticaria pigmentosa, prurigo nodularis, lichen sclerosus et atrophicus, T‐cell lymphoma, keratosis lichenoides chronica, chronic and some rare, sclerosing skin diseases. Methods: The data 230 patients treated with low‐dose, medium‐dose high‐dose UVA1 therapy during 6 years were retrospectively analysed. mean single dose (J/cm 2 ), number irradiations total )...
Duas irmãs com doença de Hailey-Hailey, lesões recorrentes - uma em axilas e outra região inguinal -, resposta limitada aos tratamentos clássicos. Elas foram tratadas aplicação toxina botulínica tipo A. Observamos que houve importante melhora na paciente tratada remissão completa cujas sofreram tratamento. Além disso, foi possível poupar uso antibióticos sistêmicos corticoides tópicos. O alto custo é um fator restritivo para rotineiro estudos maiores são necessários definir eficácia relação...
PurposeCDKN2A is the main high-risk melanoma-susceptibility gene, but it has been poorly assessed in Latin America. We sought to analyze CDKN2A and MC1R patients from America with familial sporadic multiple primary melanoma (SMP) compare data those for Spain establish bases genetic counseling America.MethodsCDKN2A were sequenced 186 American Argentina, Brazil, Chile, Mexico, Uruguay, 904 Spanish patients. Clinical phenotypic obtained.ResultsOverall, 24 14% of melanoma-prone families Spain,...
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The improved knowledge of clinical, morphologic, and epidemiologic heterogeneity melanoma in the context multiple primary familial melanomas may improve prevention, diagnosis, prognosis melanoma.To characterize reflectance confocal microscopy (RCM) morphologic patterns melanomas.In this cross-sectional, retrospective study, patients a hospital-based referral center were recruited from March 1, 2010, through August 31, 2013; data analysis was conducted September 2013, May 2014. Consecutive...
<i>Background:</i> Kaposi’s sarcoma (KS) is an unusual, clinically polymorphic, vascular neoplasm with genetic, infectious, environmental and immunological pathogenesis. Reflectance confocal microscopy (RCM) made in vivo noninvasive imaging of the skin possible has been used for evaluation several diseases offering important microscopic information. <i>Objective:</i> The purpose our study to describe RCM features KS correlate them histopathology evaluating effective...
Abstract Background Patients with familial melanoma or multiple primary represent a high‐risk population to hereditary melanoma. Mutations in susceptibility genes, such as CDKN2A, CDK4 and MC1R, have been associated the development of Objectives The purpose this study was determine genotypic background patients and/or southern Brazil. Methods This analysed 33 cases (5 28 from families at least two well documented cases) 29 controls. Genomic analysis CDKN2A genes by PCR‐SSCP sequencing direct...
Agminated nevus is a cluster group of melanocytic nevi confined to localized area the body. There are many pigmented lesions described in literature as agminated, such blue nevi, multiple lentigines and Spitz but only few cases congenital agminated have been described. We report case male child who presented with emphasizing importance physical examination, dermoscopy, histopathological evaluation, differential diagnosis follow up rule out possibility dysplastic or malignant changes.
Individuals from melanoma-prone families have similar or reduced sun-protective behaviors compared to the general population. Studies on trends in sun-related been temporally and geographically limited.
O carcinoma basocelular é o câncer mais frequente dos seres humanos e possui diversos padrões de apresentação à dermatoscopia. padrão em arco-íris um achado dermatoscópico pouco frequente, presente lesões malignas benignas, mas que no contexto correto pode auxiliar diagnóstico malignidades. Neste artigo discutiremos a relevância do para basocelular. Um homem 82 anos idade foi diagnosticado com dermatoscopia apresentava arco-íris, crosta hemática, áreas hiperceratose, escamas, vasos atípicos,...
Melanoma is a malignant tumor which develops from melanocytic cells. Leukoderma, dened as reduction or absence of skin pigmentation, and often associated either to the melanoma itself its treatment. Immunotherapy with checkpoint inhibitors one treatments currently available for metastatic melanoma, use frequently causes development leukoderma. In this manuscript we report cases 4 patients developed leukoderma following immunotherapy treatment explore role prognostic factor modality