A5078107533- Intestinal and Peritoneal Adhesions
- Hernia repair and management
- Prostate Cancer Diagnosis and Treatment
- Orthopedic Infections and Treatments
- Minimally Invasive Surgical Techniques
- Reconstructive Surgery and Microvascular Techniques
- 3D Printing in Biomedical Research
- Urinary Bladder and Prostate Research
- Transplantation: Methods and Outcomes
- Pneumonia and Respiratory Infections
- Reconstructive Facial Surgery Techniques
- Surgical Sutures and Adhesives
- Inhalation and Respiratory Drug Delivery
- Asthma and respiratory diseases
- Tracheal and airway disorders
- Bacterial Infections and Vaccines
- Electrospun Nanofibers in Biomedical Applications
- Whipple's Disease and Interleukins
- Helicobacter pylori-related gastroenterology studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Sperm and Testicular Function
- Orthopaedic implants and arthroplasty
- Abdominal Surgery and Complications
- Respiratory viral infections research
- Infective Endocarditis Diagnosis and Management
Medizinische Hochschule Hannover
2015-2019
Investigation of basic chronic inflammatory mechanisms and development new therapeutics targeting the respiratory tract requires appropriate testing systems, including those to monitor long- persistence. Human precision-cut lung slices (PCLS) have been demonstrated mimic human potential an alternative, ex-vivo system replace or augment in-vitro animal models. So far, most research on PCLS has conducted for short cultivation periods (≤72 h), while analyses slowly metabolized require long-term...
Abdominal operations are followed by adhesions, a prevalent cause of abdominal pain, and the most frequent for bowel obstruction secondary female infertility. This rat study addresses adhesion prevention capability Adept(®), Interceed(®), Seprafilm(®), novel device, 4DryField(®) PH which is provided as powder generates its effect gel.Sixty-eight male Lewis rats had cecal abrasion creation an equally sized wall defect, were grouped randomly: A control group without treatment (n=10); two...
Is the regionalization of epididymitis related to epididymal segmentation? We show for first time that luminal ascent bacteria is strictly gated by segment boundaries, involving ductal constriction adjacent infected area. The duct a continuous, unbranched tube, coiled into segments are divided connective tissue septa. Sonographic analysis indicates swelling associated with predominant in cauda region. Epididymal segmentation has never been investigated context pathological alterations....
Whipple's disease (WD) is a rare chronic systemic infection with wide range of clinical symptoms, routinely diagnosed in biopsies from the small intestine and other tissues by periodic acid-Schiff (PAS)-diastase staining immunohistological analysis specific antibodies. The aim our study was to improve pathological diagnosis WD. Therefore, we analysed potential fluorescence situ hybridization (FISH) for diagnosing WD, using Tropheryma (T.) whipplei probe. 19 formalin-fixed paraffin-embedded...
Background: Adhesions to intraperitoneally implanted meshes (IPOM) are a common problem following hernia surgery and may cause severe complications.Recently, we showed that missing peritoneal coverage of the intestine is decisive factor for adhesion formation 4DryField ® PH (4DF) gel significantly prevents intestine-to-mesh adhesions even with use uncoated Ultrapro polypropylene mesh (UPM).The present study investigates prevention capability coated Parietex (PTM) Proceed (PCM) in comparison...
Nasopharyngeal colonization with Streptococcus pneumoniae (Spn) is an important precondition for the development of pneumococcal pneumonia. At same time, nasopharyngeal Spn has been shown to mount adaptive immune responses against in mice and humans. Cellular compartment, including nasal‐associated lymphoid tissue, their importance developing are poorly defined. We show that S. led substantial expansion dendritic cells (DCs) both tissue mice. Depletion DCs achieved by either diphtheria toxin...
Meshes implanted intraperitoneally are known to cause adhesions potentially resulting in complications such as chronic pain, enterocutaneous fistula, or mesh infection. This study introduces a model for investigation of intestine-to-mesh and evaluates whether missing visceral peritoneum is causative.In 18 rats, rectangular 1.5 x 2 cm patches an uncoated polypropylene (Ultrapro(®)) were sewn the inner abdominal wall next cecum. Additionally, meso-suture ensured contact between cecum mesh....
Background: As the number of arthroplasties performed increases, periprosthetic joint infection (PJI) represents a common and challenging problem. The Musculoskeletal Infection Society (MSIS) recommends diagnosing PJI according to its guidelines. aim current study was assess whether fluorescence in situ hybridization (FISH) analysis formalin-fixed paraffin-embedded membranes can successfully improve diagnosis patients with orthopaedic implants. Methods: We retrospectively analyzed 88...
Purpose: Ideal approaches and materials for reconstruction of large chest wall defects remain a topic debate. We sought to explore the suitability reinforced nanostructured cellulose (NC) patch in an animal model. Materials Methods: In four domestic pigs, standardized 10 × cm defect was created by resecting three rib segments. Subsequently reconstructed via biosynthetic NC (16 12 cm) polytetrafluoroethylene mesh. After 1, 2, 4, 5 months respectively, gross examination patches performed...