- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Congenital gastrointestinal and neural anomalies
- RNA modifications and cancer
- Analytical Chemistry and Sensors
- Advanced Nanomaterials in Catalysis
- Respiratory viral infections research
- Ferroptosis and cancer prognosis
- Viral Infections and Immunology Research
- Nanocluster Synthesis and Applications
- Immune Cell Function and Interaction
- Carbon and Quantum Dots Applications
- Pancreatic and Hepatic Oncology Research
- Immunotherapy and Immune Responses
- Lung Cancer Treatments and Mutations
- Animal Disease Management and Epidemiology
- Horticultural and Viticultural Research
- CO2 Reduction Techniques and Catalysts
- Ocular and Laser Science Research
- Maternal and Perinatal Health Interventions
- Historical and Scientific Studies
- Cancer-related molecular mechanisms research
- Estrogen and related hormone effects
- Access Control and Trust
- Fibroblast Growth Factor Research
Qilu Hospital of Shandong University
2025
Central South University
2018-2024
Tianjin Medical University Cancer Institute and Hospital
2024
State Grid Hunan Electric Power Company Limited
2024
State Key Laboratory of Powder Metallurgy
2024
Hunan Xiangdian Test Research Institute (China)
2024
Wenzhou City People's Hospital
2024
Shandong University
2023
First People's Hospital of Chongqing
2022
Tianjin Medical University General Hospital
2021
A sensing platform based on the fluorescence quenching ability of polydopamine nanospheres was developed for assay biomolecules.
Abstract Ferroptosis suppressor protein 1 (FSP1, also known as AIMF2, AMID or PRG3) is a recently identified glutathione-independent ferroptosis 1–3 , but its underlying structural mechanism remains unknown. Here we report the crystal structures of Gallus gallus FSP1 in substrate-free and ubiquinone-bound forms. The reveal FAD-binding domain NAD(P)H-binding domain, both which are shared with AIF NADH oxidoreductases 4–9 characteristic carboxy-terminal well. We demonstrate that crucial for...
Abstract: Purpose : Regulatory T cells (T‐reg) that control harmful autoimmune in the periphery may also suppress immune response against cancer. In this study we investigated possible involvement of CD4 + CD25 high T‐reg impairment patients with acute myeloid leukemia (AML). Experimental design The frequencies and phenotypes peripheral blood AML were determined by flow cytometry. To assess functional activity cells, , − sorted from mononuclear FACS Vantage. immunoregulatory properties...
Autoimmune hemolytic anemia (AIHA) is a type of anemia. In this condition, the body produces anti-red blood cell autoantibodies due to immune dysfunction. This results in accelerated destruction red cells. According best temperature for stick cells, there are three types: warm antibody (wAIHA), cold (cAIHA), and mixed warm-cold (mAIHA). article presents case acute severe autoimmune an elderly male patient. The patient exhibited symptoms including jaundice skin, mucous membranes, urine with...
Adjuvant lenvatinib in combination with transarterial chemoembolization (TACE) has demonstrated prolonged disease-free survival hepatocellular carcinoma patients at high risk of recurrence post-resection. Here, we present the case a 68-year-old woman who developed serious side effects including pemphigus erythematosus (PE) linked to usage. Initially treated for breast cancer radical surgery April 2018 followed by adjuvant therapy, she was later diagnosed liver cancer, initially mistaken...
Scientific evidence has linked diabetes to a higher incidence and increased aggressiveness of breast cancer; however, mechanistic studies the numerous regulators involved in this process are insufficiently thorough. Advanced glycation end products (AGEs) play an important role chronic complications diabetes, but mechanisms AGEs cancer largely unexplored. In study, we first demonstrate that high AGE levels tissues associated with diabetic state poor patient outcomes. Furthermore, interact...
Highly crystallized micro/nano-sized Y<sub>2</sub>O<sub>2</sub>S were prepared through a one-pot mild solvothermal synthesis. By simply adjusting the amount of initial sulfur powder, morphology and assembled structures can be well controlled.
With the large number of distributed users in microgrid, order to efficiently utilize massive microgrid measurements and accurately assess potential take part demand response, this paper proposed a data-driven visual assessment scheme users' response potential. Firstly, according daily operation power data four typical users, evaluation index was designed, weighted value formed by objective weighting method. Then, system visualized based on deep auto-encoder improve convenience perceptual...
4537 Background: Belzutifan, a first-in-class HIF-2α inhibitor, alone or in combination with VEGFR-TKI, has shown durable antitumor activity first- and subsequent-line settings of advanced ccRCC. LITESPARK-010 (NCT05030506) is phase 1, 2-cohort, open-label study belzutifan + len, without pembrolizumab, Chinese pts We present preliminary results cohort 1. Methods: adults histologically confirmed ccRCC who had 1-3 prior treatment regimens received 120 mg PO QD for 3 wk followed by len 20 until...
<title>Abstract</title> The inability of surgical biopsy to monitor the dynamic evolution cancer cells hampers its capacity reflect real-time tumor heterogeneity. Circulating (CTCs), as a crucial target in liquid biopsy, offer novel approach for accurate monitoring tumors. However, rarity and complex phenotype resulting from epithelial mesenchymal transition pose challenges conventional methods such CellSearch immunohistochemistry, which have insufficient ability simultaneous phenotyping...