Guilherme Thomaz Pereira Brancini

ORCID: 0000-0001-9726-6056
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Research Areas
  • Photodynamic Therapy Research Studies
  • Entomopathogenic Microorganisms in Pest Control
  • Insect and Arachnid Ecology and Behavior
  • Antifungal resistance and susceptibility
  • Nanoplatforms for cancer theranostics
  • Ocular Infections and Treatments
  • Insect Resistance and Genetics
  • Nematode management and characterization studies
  • Fungal Biology and Applications
  • Essential Oils and Antimicrobial Activity
  • Plant Pathogens and Fungal Diseases
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Insect Pest Control Strategies
  • bioluminescence and chemiluminescence research
  • Biosensors and Analytical Detection
  • Listeria monocytogenes in Food Safety
  • Insect symbiosis and bacterial influences
  • Antibiotic Resistance in Bacteria
  • Indoor Air Quality and Microbial Exposure
  • Insects and Parasite Interactions
  • Cannabis and Cannabinoid Research
  • Genetics, Bioinformatics, and Biomedical Research
  • Fungal Infections and Studies
  • Algal biology and biofuel production
  • Microbial Natural Products and Biosynthesis

Universidade de São Paulo
2014-2024

Universidade de Ribeirão Preto
2021-2024

Universidad de Sevilla
2019

Abstract This study aimed to assess the ultrapure cannabidiol (CBD) antibacterial activity and investigate of combination CBD + polymyxin B (PB) against Gram-negative (GN) bacteria, including PB-resistant bacilli (GNB). We used standard broth microdilution method, checkerboard assay, time-kill assay. exhibited Gram-positive lipooligosaccharide (LOS)-expressing GN diplococcus (GND) ( Neisseria gonorrhoeae , meningitidis Moraxella catarrhalis ), Mycobacterium tuberculosis but not GNB. For most...

10.1038/s41598-022-10393-8 article EN cc-by Scientific Reports 2022-04-19

The unbridled dissemination of multidrug-resistant pathogens is a major threat to global health and urgently demands novel therapeutic alternatives. Antimicrobial photodynamic therapy (aPDT) has been developed as promising approach treat localized infections regardless drug resistance profile or taxonomy. Even though this technique known for more than century, discussions speculations regarding the biochemical mechanisms microbial inactivation have never reached consensus on what primary...

10.1111/php.13685 article EN Photochemistry and Photobiology 2022-08-01

Abstract Neurospora crassa is an established reference organism to investigate carotene biosynthesis and light regulation. However, there little evidence of its capacity produce secondary metabolites. Here, we report the role fungal-specific regulatory velvet complexes in development metabolism (SM) N. crassa. Three proteins VE-1, VE-2, VOS-1, a putative methyltransferase LAE-1 show light-independent nucleocytoplasmic localization. Two distinct complexes, heterotrimeric VE-1/VE-2/LAE-1...

10.1534/genetics.119.302277 article EN Genetics 2019-05-08

Soil biota has a crucial impact on soil ecology, global climate changes, and effective crop management studying the diverse ecological roles of dipteran larvae deepens understanding food webs. A multi-omics study Pseudolycoriella hygida comb. nov. (Diptera: Sciaroidea: Sciaridae) aimed to characterize carbohydrate-active enzymes (CAZymes) for litter degradation in this species. Manual curation 17,881 predicted proteins Psl. genome identified 137 secreted CAZymes, which 33 are present saliva...

10.1016/j.isci.2023.106449 article EN cc-by-nc-nd iScience 2023-03-20

Metarhizium acridum is an entomopathogenic fungus commonly used as a bioinsecticide. The conidium the fungal stage normally employed field inoculum in biological control programs and must survive under conditions such high ultraviolet-B (UV-B) exposure. Light, which important stimulus for many fungi, has been shown to induce production of M. robertsii conidia with increased stress tolerance. Here we show that two-hour exposure white or blue/UV-A light fast-growing mycelium induces tolerance...

10.1093/femsle/fnw036 article EN FEMS Microbiology Letters 2016-02-15

G-protein coupled receptors (GPCRs) are extracellular signaling that sense environmental cues. Fungi their environment primarily through GPCR-mediated pathways, which, in turn, regulate fungal development, metabolism, virulence, and mycotoxin biosynthesis. Aspergillus fumigatus is an important human pathogen causes aspergillosis, a heterogeneous group of diseases present wide range clinical manifestations. Here, we investigate detail the role GPCRs GprM GprJ growth gene expression. for...

10.1128/mbio.02458-20 article EN mBio 2020-10-07

Light is an important stimulus for fungi as it regulates many diverse and biological processes. Metarhizium acridum entomopathogenic fungus currently used the control of insect pests. The success this approach heavily dependent on tolerance to environmental stresses. It was previously reported that light exposure increases ultraviolet radiation in M. There no information literature about how globally influences gene expression fungus. We employed a combination mRNA-Sequencing high-throughput...

10.1534/g3.119.400430 article EN cc-by G3 Genes Genomes Genetics 2019-07-11

Abstract Assessing the in vitro toxicity of compounds on cell cultures is an important step during screening candidate molecules for diverse applications. Among strategies employed to determine cytotoxicity, MTT, neutral red, and resazurin are commonly used. Methylene blue (MB), a phenothiazinium salt, has several uses, such as dye, redox indicator, even treatment human disease health conditions, malaria methemoglobinemia. However, MB only been sparsely used cellular indicator. As viability...

10.1038/s41598-023-36721-0 article EN cc-by Scientific Reports 2023-06-23
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