A5103049461- Lymphoma Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Immune Cell Function and Interaction
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Acute Myeloid Leukemia Research
- Circular RNAs in diseases
- Monoclonal and Polyclonal Antibodies Research
- Viral-associated cancers and disorders
- CAR-T cell therapy research
- RNA modifications and cancer
- Pluripotent Stem Cells Research
- Chronic Lymphocytic Leukemia Research
- Hematological disorders and diagnostics
- Animal Nutrition and Physiology
- Mesenchymal stem cell research
- Reproductive System and Pregnancy
- Estrogen and related hormone effects
- Multiple Myeloma Research and Treatments
- Effects of Radiation Exposure
- Selenium in Biological Systems
- Veterinary Equine Medical Research
- Bone and Joint Diseases
- Extracellular vesicles in disease
- Effects and risks of endocrine disrupting chemicals
Sir Run Run Shaw Hospital
2025
Zhejiang University
2025
Liaocheng University
2019-2025
Peking University
2014-2023
Peking University Third Hospital
2014-2023
Xiamen University
2023
Anhui University of Technology
2023
Soochow University
2017-2019
First Affiliated Hospital of Soochow University
2017-2019
Nanjing Medical University
2016-2018
Dysregulated expression of specific microRNAs (miRNAs) in serum has been recognised as promising diagnostic biomarkers for colorectal cancer (CRC). In the initial screening phase, a total 32 differentially expressed miRNAs were selected by quantitative reverse transcription polymerase chain reaction (qRT-PCR) based Exiqon panel with 3 CRC pool samples and 1 normal control (NC) pool. Using qRT-PCR, further confirmed training (30 VS. 30 NCs) testing stages (136 90 NCs). We identified that...
To develop a weight management nutrition knowledge questionnaire for Chinese adults (C-WMNKQ) and to test its reliability validity. We evaluated the content validity of using expert consultation method, face through pre-survey, eliminated questions that did not meet criteria item difficulty, differentiation, inter-item correlation. verified construct known-groups comparison method. Correlation analysis by comparing it with general (C-GNKQ) was conducted criterion evaluation. The internal...
This review article highlights the surveillance of bacterial, viral, and parasitic diseases in donkey populations China. Key findings highlight significant threats from Equine herpesviruses (EHV-8 EHV-1), which cause encephalitis, abortion, respiratory distress. Several infections including Giardia duodenalis, Cryptosporidium spp., Enterocytozoon bieneusi, Toxoplasma gondii present important zoonotic concerns across multiple regions Additionally, this synthesizes current knowledge on...
The production of high-quality specialty meats has emerged as a prominent research focus within the livestock industry, under broader concept big food. However, composition and variances volatile compounds (VOCs) in donkey meat (DM) horse (HM) remain unclear, which complicates their effective identification. In present study, VOCs DM HM were analyzed using gas chromatography–ion mobility spectrometry (GC-IMS) combination with multivariate analysis. Our results indicate that total 39...
B7-H3 (CD276), known as a member of B7 immunoregulatory family, is type I transmembrane glycoprotein aberrantly expressed in numerous types cancer and associated with poor prognosis. However, the role oncogenesis chemosensitivity mantle cell lymphoma (MCL) remains unknown. We determined effects downregulating expression on tumor progression sensitivity chemotherapeutic drug lymphoma. knockdown was performed using lentivirus transduction Maver Z138 lines, respectively. The proliferation,...
Helicobacter pylori infection is the main cause of chronic gastritis, peptic ulcer, and gastric cancer. Tip-α a newly identified carcinogenic factor present in H. pylori. TRAF3 can activate NF-κB by both canonical noncanonical signaling pathways. In this study, we found that expression was upregulated, while microRNA-3178 (miR-3178) decreased pylori-positive tissues but not pylori-negative tissues.GES-1 cells were incubated with 12.5 μg/mL recombinant (rTip-α) RPMI1640 for 2 hours. After...
Background: Recent studies have highlighted the important roles of long non-coding RNAs (lncRNAs) in pancreatic adenocarcinoma (PCa) prognosis. However, most explored a limited number lncRNAs based on small sample size. Methods: Systematic and comprehensive analysis data from The Cancer Genome Atlas (TCGA) was performed to identify panel lncRNA signature for predicting prognosis PCa. Results: A total 160 PCa patients with complete clinical were included our study. Twelve identified be...
Summary: Four groups of pregnant rats were used to study the effects dietary supplements folic acid (FA) alone or a mixture FA, vitamins (Vit), and amino acids (AA) on teratogenic phenytoin (PHT). Groups A, B, C received intraperitoneal (i.p.) injections high‐dose (75 mg/kg/day) (PHT) between 9 11 days gestation, while controls, group D, distilled water. The diet was modified in A B. Group Vit, AA, B FA supplementation alone. D regular diet. We found that PHT, when administered without...
T-cell acute lymphoblastic leukemia/lymphoma (T-ALL/LBL) is an aggressive hematological disorder that sensitive to chemotherapy; however, it exhibits frequent relapse rates. Platinum-containing therapeutics are the first-line salvage regimens used in treatment of relapsed or refractory T-ALL/LBL. The selenium-platinum compound EG-Se/Pt obtained from combination selenium-containing molecules (EG-Se) with cisplatin (CDDP); its anticancer properties have been poorly investigated. In present...
The maternal intestinal microbial community changes dramatically during pregnancy and plays an important role in animal growth, metabolism, immunity reproduction. However, our understanding of microbiota compositional dynamics the whole period donkey is incomplete. This study was carried out to evaluate gut alterations as well correlation with serum biochemical indices, comparing pregnant donkeys non-pregnant donkeys. A total 18 (including EP, early-stage pregnancy; MP, middle-stage LP,...
<p>This study aimed to investigate the effect of sundried big-leaf mulberry (BLM) as a replacement for alfalfa on growth performance, digestibility nutrients, nitrogen (N) utilisation and meat quality in New Zealand White rabbits. One hundred sixty weaned rabbits, aged 35±1 d with body weight 755±26 g, were randomly assigned 4 treatments 20 replicates 2 rabbits (1 male 1 female) each. Animal performance was evaluated between 35th 77th age 40 animals per treatment. The coefficients...
Objective: Diffuse Large B-Cell Lymphoma (DLBCL) is a common and frequently occurring subtype of Non-Hodgkin (NHL). The effective treatment prognosis DLBCL are still urgently needed to be explored. This article aims shed light on the connection between survival NR3C1 expression levels. Methods: First, we divided 952 patients into an high-expression group low-expression compared baseline characteristics two groups. Second, used multivariate analysis predict dependent variable for age,...
To establish a new inducing system for differentiation of human embryonic stem (ES) cells to dendritic (DC), and further explore how microRNA-223 (miR-223) regulates DC from ES cells.Human were cultured on plates coated by IV type collagen differentiated into hematopoietic stem/progenitor cells, common myeloid progenitor step via adding different growth factors. The identified morphology, flow cytometry colony forming unit (CFU) assays. Human transfected with lentiviral vectors overexpress...
Abstract An online pattern recognition method of lower limb movements is proposed based on the personalized surface electromyography (sEMG) signals, and corresponding experimental researches are performed in rehabilitation training. Further, a wireless wearable acquisition instrument used. Based this instrument, host computer for personal real-time control training developed. Three time-domain features two nonlinear dynamics selected as joint set characteristic values sEMG signals. Then...
This study was purposed to establish a new inducing system for differentiation of human embryonic stem cells into hematopoietic progenitor and explore the effect different extracellular matrices (DEM) on production cells. The 3 kinds matrices-matrigel, fibronectin IV type collagen (collagen IV) were chosen package cultured plates, direct adherent culture matrix used, growth factors added plates induce colony forming unit assay used determine yielded cells, flow cytometry real-time...