A5100449597- Rangeland Management and Livestock Ecology
- Cancer, Hypoxia, and Metabolism
- Environmental and Agricultural Sciences
- Educational Reforms and Innovations
- Pasture and Agricultural Systems
- Plant Ecology and Soil Science
- Metabolomics and Mass Spectrometry Studies
- Cancer, Lipids, and Metabolism
- Medicinal Plant Pharmacodynamics Research
- Medical Research and Treatments
- Water Quality Monitoring and Analysis
- Natural Compounds in Disease Treatment
- Free Radicals and Antioxidants
- Retinoids in leukemia and cellular processes
- Inorganic and Organometallic Chemistry
- Neuroscience and Neuropharmacology Research
- Natural product bioactivities and synthesis
- Bioinformatics and Genomic Networks
- Bacterial biofilms and quorum sensing
- Plant Growth Enhancement Techniques
- Cell death mechanisms and regulation
- Forest, Soil, and Plant Ecology in China
- Phytochemicals and Antioxidant Activities
- Milk Quality and Mastitis in Dairy Cows
- Ginseng Biological Effects and Applications
Sun Yat-sen University
2013-2025
Inner Mongolia Agricultural University
2025
Sun Yat-sen University Cancer Center
2025
Hunan Provincial People's Hospital
2024
China Automotive Engineering Research Institute
2024
Xi'an Polytechnic University
2020-2024
Fudan University
2013-2024
Peking University
2020-2024
Peking University Third Hospital
2020-2024
Nanjing University of Posts and Telecommunications
2024
Neurons are flexible electrophysiological entities in which the distribution and properties of ionic channels control their behaviors. Through simultaneous somatic axonal whole-cell recording layer 5 pyramidal cells, we demonstrate a remarkable differential expression slowly inactivating K + currents. Depolarizing axon, but not soma, rapidly activated low-threshold, inactivating, outward current that was potently blocked by low doses 4-aminopyridine, α-dendrotoxin, rTityustoxin-Kα. Block...
Background The COVID‐19 pandemic has powerfully shaped people’s lives. current work investigated the emotional and behavioral reactions people experience in response to through their internet searches. We hypothesised that when prevalence rates of increase, would more fear, which turn predict searches for protective behaviors, health‐related knowledge, panic buying. Methods Prevalence United States, Kingdom, Canada, Australia were used as predictors. Fear‐related emotions, seeking buying...
ABSTRACT While copper is an essential trace element in biology, pollution of groundwater from has become a threat to all living organisms. Cellular mechanisms underlying toxicity, however, are still not fully understood. Previous studies have shown that iron-sulfur proteins among the primary targets toxicity Escherichia coli under aerobic conditions. Here, we report that, anaerobic conditions, E. cells even more susceptible medium. Whereas addition 0.2 mM copper(II) chloride LB...
Esophageal squamous cell carcinoma (ESCC) is a major histological subtype of esophageal cancer with inferior prognosis. Here, we conducted comprehensive transcriptomic, proteomic, phosphoproteomic, and metabolomic characterization human, treatment-naive ESCC paired normal adjacent tissues (cohort 1, n = 24) in an effort to identify new molecular vulnerabilities for potential therapeutic targets. Integrative analysis revealed small group genes that were related the active posttranscriptional...
Particulate matter (PM) has been found to elevate the risk of pulmonary embolism (PE) onset. Among contributors PM, dust PM stands as second natural source, and its emissions are escalating due climate change. Despite this, information on effect PE onset is scarce. Hence, this study aims investigate impact PM10, PM2.5–10, PM2.5 A nationwide time-stratified case-crossover was conducted between 2015 2020, using data from 18,616 cases across 1921 hospitals. The analysis employed a conditional...
The key to the construction of high-level specialty groups lies in generation agglomeration effect. It shows three effects: scale, sharing and innovation. analysis 242 samples based on entropy weight TOPSIS method that innovation effect is more prominent than three, but overall level not high, category difference obvious. optimization depends reinforcement holistic concept, improvement mechanisms establishment quality assurance system.
Abstract Under current dairy cow feeding conditions, the conversion efficiency of dietary nitrogen into milk protein is less than 30%. A thorough understanding amino acid (AA) uptake and utilization in mammary response to AA supply essential for accurately modeling nutritional requirements. This study utilized bovine epithelial cells (BMEC) as a model investigate effects increasing total (EAA) concentrations (0.00, 0.97, 1.94, 3.88, 7.76 mM) on uptake, metabolism, casein synthesis. The...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDetection of a Ruthenabenzene, Ruthenaphenoxide, and Ruthenaphenanthrene Oxide: The First Metalla Aromatics Second-Row Transition MetalJing Yang, William M. Jones, JaNeille K. Dixon, Neil T. AllisonCite this: J. Am. Chem. Soc. 1995, 117, 38, 9776–9777Publication Date (Print):September 1, 1995Publication History Published online1 May 2002Published inissue 1 September...
Despite much recent interest, it remains unclear what determines the rate of evolution gene expression. To study this issue we develop a new measure, called "Expression Conservation Index" (ECI), to quantify degree tissue-expression conservation between two homologous genes. Applying measure large set expression data from human and mouse, show that tissue tends evolve rapidly for genes are expressed in only limited number tissues, whereas can be conserved long time tissues. Therefore,...
The adhesion of bacteria to metal oxide and other mineral surfaces may involve bacterial siderophores, many which contain hydroxamic acid (Ha) ligands. adsorption behavior the siderophore-related ligands acetohydroxamic acid, N-methylformohydroxamic N-methylacetohydroxamic 1-hydroxy-2-piperidone on titanium dioxide thin films has been investigated using in situ ATR-IR spectroscopy with variation concentration pH. All were found adsorb strongly TiO2 surface as hydroxamate ions form bidentate...
The initiation of biofilm formation is poorly understood, and in particular, the contribution chemical bond between bacterial cells metal surfaces has received little attention. We have previously used situ infrared spectroscopy to show, during initial stages Pseudomonas aeruginosa formation, coordinate covalent bonds titanium dioxide particle films pyoverdine, a mixed catecholate hydroxamate siderophore. Here we show using that pyoverdine can also form with Fe2O3, CrOOH, AlOOH. Adsorption...
ABSTRACT In this paper, ultraperformance liquid chromatography/quadrupole time‐of‐flight mass spectrometry (UPLC‐Q‐TOF/MS) and the MetaboLynx™ software combined with defect filtering were applied to identity metabolites of isoquercitrin using an intestinal mixture bacteria 96 isolated strains from human feces. The incubated samples collected for 72 h in anaerobic incubator extracted ethyl acetate analyzed by UPLC‐Q‐TOF/MS within 10 min. parent compound five identified eight strains,...
Voltage-gated K(+) (KV) channels play critical roles in shaping neuronal signals. KV distributed the perisomatic regions and thick dendrites of cortical pyramidal neurons have been extensively studied. However, properties regulation thin axons remain unknown. In this study, by performing somatic axonal patch-clamp recordings from layer 5 prefrontal slices, we showed that rapidly inactivating A-currents mediated transient currents evoked action potential (AP) waveform command (KAP) at soma,...
Colon cancer is the second most lethal malignancy worldwide. A better understanding of colon at molecular level may increase overall survival rates. Previous studies have indicated that prolyl 4‑hydroxylase, β polypeptide (P4HB) associated with tumorigenesis in cancer; however, its role and mechanisms remain unclear. In present study, cellular responses to P4HB human cell lines were investigated by proliferation apoptosis assays, western blotting, immunohistochemistry. The results showed...
Lignin is the most abundant aromatic source of natural products, but developing efficient catalysts to depolymerize it into valuable monophenol with high yield and unique selectivity remains a challenge. Herein, we report Ru single-atom catalyst (SAC) supported on rod CeO2 oxygen vacancies (Ov) for depolymerization birch dioxane acidolysis lignin (DAL). A near-theoretical maximum (14.8 wt %) good 4-n-propenyl guaiacol (51.4%), as well stability, was achieved. The calculated turnover (TON)...
// Xiaoling Zhang 1, 2, * , Jing Yang Minjian Chen 3, 4, Lei Li 2 Fei Huan 5 Aiping 4 Yanqing Liu Yankai Xia Jin-ao Duan 6 Shiping Ma 1 Department of Pharmacology Chinese Materia Medica, China Pharmaceutical University, Nanjing 210009, Hygienic Analysis and Detection, Medical 211166, 3 State Key Laboratory Reproductive Medicine, Institute Toxicology, Modern Toxicology Ministry Education, Safety Assessment Research Center for Drug, Pesticide Veterinary Drug Jiangsu Province, National Local...
Excessive activation of NLRP3 inflammasome and down-regulation Sirt1/Smad3 deacetylation pathway play a significant role in the evolution renal fibrosis. In China, it has been well known that Chinese herbal medicine is markedly effective treating chronic kidney disease (CKD). Shen Shuai IIRecipe (SSR) used clinically for more than 20 years confirmed to be improvements function However, specific mechanisms under efficacy require further research. The purpose this study was evaluate whether...