A5034133524- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Esophageal and GI Pathology
- Colorectal Cancer Screening and Detection
- Esophageal Cancer Research and Treatment
- Gastrointestinal disorders and treatments
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Colorectal Cancer Surgical Treatments
- Neuroendocrine Tumor Research Advances
- Eosinophilic Esophagitis
- Tracheal and airway disorders
- Colorectal Cancer Treatments and Studies
- Intraperitoneal and Appendiceal Malignancies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gallbladder and Bile Duct Disorders
- Lung Cancer Research Studies
- Genetic factors in colorectal cancer
- Hepatocellular Carcinoma Treatment and Prognosis
- Medical Imaging and Pathology Studies
- Neurofibromatosis and Schwannoma Cases
- Cancer, Stress, Anesthesia, and Immune Response
- Educational Robotics and Engineering
National Center For Child Health and Development
2025
NTT Medical Center
2009-2024
National Institute of Technology, Ichinoseki College
2024
Yokkaichi Municipal Hospital
2024
Red Cross Hospital
2015-2024
Yokohama City University
2008-2021
State of The Art
2012
Optica
2012
Catalina Scientific (United States)
2012
Morishita Jintan (Japan)
2011
Colorectal cancer (CRC) is one of the most common neoplasms and endoscopic submucosal dissection (ESD) an effective treatment for early-stage CRC. However, it has been observed that patients undergoing ESD often complain pain, even if successfully performed. Risk factors such pain still remain unknown. The aim this study was to explore risk post-colorectal coagulation syndrome (PECS).This a prospective multicenter observational trial (UMIN000016781) conducted in 106 223 who underwent between...
Although colorectal endoscopic submucosal dissection (ESD) is superior to mucosal resection (EMR) in en bloc rate, it technically quite difficult because of the anatomical and histological characteristics wall. This difficulty prevents wide spread technique. Establishment training system for ESD necessary standardize achieve wider acceptance this Herein, we describe our ESD, assess validity based on clinical outcomes learning curve trainees. Our would help procedure.
<b>Background and study aims: </b>A standard training system for endoscopic submucosal dissection (ESD) remains to be established. In this study, we evaluated the validity of our program gastric ESD. <b>Patients methods:</b> Four trainees performed ESD a total 117 lesions in 107 patients (27 30 consecutive per trainee) at tertiary referral center during 2 years program. Trainees, who already had fundamental skills knowledge needed ESD, each assisted 40 procedures, then 20 cases applied...
Abstract Aim The risk of lymph node metastasis after endoscopic resection high‐risk T1 colorectal cancer prompts additional resection. However, age and comorbidities are considered in decision‐making some surgeons opt for observation. We compared the long‐term outcomes these approaches with aim clarifying need Method This multicentre retrospective study included patients treated submucosal dissection (ESD) between January 2013 April 2021. Patients who met one or more following criteria were...
Delayed perforation following colorectal endoscopic submucosal dissection (ESD) occurs in approximately 0.4% of cases [1] [2]. Although it is rare, emergency surgery required nearly half these [3]. Endoscopic closure for such perforations rarely performed. No successful delayed using hemoclips after ESD have yet been reported. Here, we present a case colon that was successfully closed with and managed conservatively.
The over-the-scope (OTS) clip is effective for defect closure during endoscopic treatment [1] [2]. OTS has been reported to be in preventing delayed perforation and bleeding, especially after duodenal resection [3]. However, adverse events associated with the itself have reported, including perforation, infection, failure attach [4] [5].
Endoscopic submucosal dissection (ESD) is a standard treatment for early gastrointestinal cancer, but carries risks of delayed bleeding and perforation. closure the post-ESD ulcer can reduce these [1]. We previously reported "clip with line pulley securing" (CLiPS) technique [2] [3] [4], simple cost-effective method that allows without scope reinsertion. Mucosa-to-mucosa may however result in dehiscence, particularly large mucosal defects. To address this limitation, we developed modified...
<title>Abstract</title> Background Hypernatremia is associated with increased mortality risk in pediatric patients. However, its impact on outcomes remains unclear. This study aimed to clarify the clinical backgrounds of contemporary children hypernatremia and identify prognostic factors, including organ dysfunction mortality. Methods We conducted a retrospective observational under 18 years age (serum sodium ≥150 mmol/L) at tertiary hospital Japan between December 2021 May 2023. Patient...
Limited information is available on the efficacy and safety of endoscopic resection (ER) gastric submucosal tumors (SMTs) in Japanese practice where ER for extremely popular.We conducted this study to elucidate current scenario SMTs practice. Patients (from 12 institutions) with who underwent were enrolled from first case until August 2020.We 117 patients 118 lesions. The number increased over years. mean tumor size was 20 ± 7.2 (8-40) mm. growth type primarily intraluminal (90%). wound...
To investigate the impact of metabolic and lifestyle factors on erosive esophagitis in young adults.A total 5,069 people under age 40 years old were enrolled a medical survey at our institute. People with previous history upper gastrointestinal tract surgery excluded, as individuals taking medication for reflux symptoms, peptic ulcers, or malignancies. Independent significant predictors affecting presence determined by multivariate analysis.A 4,990 participants (male/female; 3,871/1,119,...
Abstract Background Cold snare defect protrusions (CSDPs) that occur after cold polypectomy (CSP) are considered indicators of incomplete polyp resection (IPR). We have sometimes experienced difficulty resecting polyps with snaring alone; in such cases, a forcible pull on the by endoscopist is necessary. call this procedure “forced CSP (FCSP).” However, no previous studies evaluated procedure. Methods This was prospective observational study. From November 2020 to June 2021, frequency,...
Introduction:Endoscopic submucosal dissection (ESD) has been developed as a minimally invasive treatment.However, in some instances, closure of post ESD defects may be necessary patients with high risk delayed bleeding, or deep muscle injury intraprocedural perforation.While hemostatic clips used to close small defects, larger is challenging.Purse-string method suitable for but require double channel scope, scope replacement, and poses alignment complexities 1).Suturing devices are costly...
With the aging of population and rising incidence thromboembolic events, usage antiplatelet agents is also increasing. There are few reports yet on management for patients undergoing colorectal endoscopic submucosal dissection (ESD).The aim this study to evaluate whether continued administration associated with an increased rate delayed bleeding after ESD.A total 1022 neoplasms in 927 were dissected at Yokohama City University Hospital its three affiliate hospitals between July 2012 June...
Since colorectal endoscopic submucosal dissection (ESD) remains technically difficult, hybrid ESD was developed as an alternative therapeutic option to achieve en bloc resection of relatively large lesions. In this feasibility study, we evaluated the safety and efficacy using a newly multifunctional snare. From June August 2016, prospectively enrolled 10 consecutive patients with non-pedunculated intramucosal tumors 20 - 30 mm in diameter. All steps were performed "SOUTEN" The knob-shaped...
Aberrant DNA methylation plays an important role in genesis of colorectal cancer (CRC). Previously, we identified Group 1 and 2 markers through genome-wide analysis, classified CRC protruded adenoma into three distinct clusters: high-, intermediate- low-methylation epigenotypes. High-methylation epigenotype strongly correlated with BRAF mutations these aberrations were involved the serrated pathway, whereas intermediate-methylation KRAS mutations. Here, investigated laterally spreading...
Endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) is performed safely and effectively in elderly patients; however, whether ESD EGC patients with frailty safe improves prognosis remains unclear.In total, 142 aged ≥80 years who underwent between September 2008 2014 were included. We compared outcomes those without frailty. Frailty was assessed using the Clinical Scale (CFS) based on a patient's status before admission. Study endpoints short- long-term clinical after...
Endoscopic resection of large pedunculated colorectal polyps is technically difficult, especially when the polyp and has such a thick stalk that it either too difficult or impossible to resect prophylactically by conventional snare. Here, we evaluated feasibility ESD for with wide stalks. 29 patients were not resectable polypectomy endoscopic mucosal enrolled in study. En bloc was achieved 28/29 polyps. One suspended case due severe fibrosis muscle retraction signs. The mean diameter heads...