A5060778465- Edible Oils Quality and Analysis
- Fatty Acid Research and Health
- Cholesterol and Lipid Metabolism
- Nutritional Studies and Diet
- Antioxidant Activity and Oxidative Stress
- Cancer, Lipids, and Metabolism
- Phytochemicals and Antioxidant Activities
- Diet and metabolism studies
- Genetic and phenotypic traits in livestock
- Animal Virus Infections Studies
- Eicosanoids and Hypertension Pharmacology
- Obesity, Physical Activity, Diet
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Gut microbiota and health
- Metabolomics and Mass Spectrometry Studies
- Atherosclerosis and Cardiovascular Diseases
- Essential Oils and Antimicrobial Activity
- Wastewater Treatment and Reuse
- Coffee research and impacts
- Paraoxonase enzyme and polymorphisms
- Dye analysis and toxicity
- Tea Polyphenols and Effects
- Iron Metabolism and Disorders
- Alcohol Consumption and Health Effects
- Diet, Metabolism, and Disease
Institut Català d'Oncologia
2022-2024
Institut d'Investigació Biomédica de Bellvitge
2022-2024
IPB University
2024
Hospital de Sant Pau
2023
Imperial College London
2017-2022
Institut d'Investigacions Biomèdiques de Barcelona
2020-2022
Instituto de Salud Carlos III
2015-2021
Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas
2019-2021
Hospital del Mar Research Institute
2014-2020
Hospital Del Mar
2013-2020
Olive oil polyphenols have shown beneficial properties against cardiovascular risk factors. Their consumption has been associated with higher cholesterol content in high-density lipoproteins (HDL). However, data on polyphenol effects HDL quality are scarce. We, therefore, assessed whether polyphenol-rich olive could enhance the main function, its efflux capacity, and some of quality-related properties, such content, size, composition.A randomized, crossover, controlled trial 47 healthy...
Abstract Background Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MetS) are implicated in the aetiology of non-communicable diseases. Our study aimed to evaluate associations between NAFLD MetS with overall cause-specific mortality. Methods We used dietary, lifestyle, anthropometric biomarker data from a random subsample 15,784 EPIC cohort participants. was assessed using index (FLI) revised definition. Indices for dysfunction–associated (MAFLD) were calculated. The...
Scope In the present study, individual colonic metabolism of main components virgin olive oil phenolic fraction was evaluated by an in vitro model using human faecal microbiota. To assess differences related to molecular structure, four standards were selected, tyrosol, hydroxytyrosol, hydroxytyrosol acetate and oleuropein. After studying pathways phenols, presence their metabolites investigated samples obtained before after sustained intake (3 weeks) a daily dose 25 mL phenol‐enriched oil....
Abstract Prospective studies assessing the association between fibre intake or fibre-rich food consumption and risk of CVD have often been limited by baseline assessment diet. Thus far, no study has used yearly repeated measurements dietary changes during follow-up. Moreover, previous included healthy selected participants who did not represent subjects at high cardiovascular risk. We diet to investigate in a Mediterranean cohort elderly adults followed-up 7216 men (55–80 years) women (60–80...
The effects of olive oil phenolic compounds (PCs) on HDL proteome, with respect to new aspects cardioprotective properties, are still unknown. aim this study was assess the impact protein cargo intake virgin (VOO) and two functional VOOs, enriched their own PCs (FVOO) or complemented thyme (FVOOT), in hypercholesterolemic subjects. Eligible volunteers were recruited from IMIM-Hospital del Mar Medical Research Institute (Spain) April 2012 September 2012. Thirty-three participants (total...
Consumption of olive oil (OO) phenolic compounds (PCs) has beneficial effects on lipid profile. HDL functionality is currently considered to be a more important issue than its circulating quantity. Our aim was assess whether functional virgin oils (FVOOs), one enriched with own PC (500 ppm; FVOO) and another OOPC (250 ppm) plus additional complementary PCs from thyme (total: 500 FVOOT (functional thyme)), could improve related properties versus OO control (80 VOO).In randomized,...
The main findings of the "Virgin Olive Oil and HDL Functionality" (VOHF) study other related studies on effect phenol-enriched virgin olive oil (VOO) supplementation cardiovascular disease are integrated in present work.VOHF assessed whether VOOs, enriched with their own phenolic compounds (FVOO) or those from thyme (FVOOT), improve quantity functionality HDL. In this randomized, double-blind, crossover, controlled trial, 33 hypercholesterolemic subjects received a control VOO (80 mg kg-1 ),...
Background Environmental enteric dysfunction (EED) is widespread throughout the tropics and in children associated with stunting other adverse health outcomes. One of hallmarks EED villus damage. In severe acute malnutrition (SAM) severity enteropathy greater short term mortality high, but metabolic consequences are unknown. Here, we characterize urinary alterations health, classic biomarkers anthropometric measurements severely malnourished Zambia. Methods/Principal findings We analysed 20...
The gut metabolism of four thyme phenolics (monoterpenes thymol and carvacrol, rosmarinic acid, eriodictyol) was evaluated in vitro. After the vitro transformations individual phenols had been studied, presence their microbial metabolites investigated human feces collected before after a sustained intake (3 weeks) 25 mL/day phenol-enriched olive oil. Results fermentation showed low degradation carvacrol. By contrast, large catabolism noted when acid eriodictyol were fermented, yielding...
We investigate the postprandial modulation of cardiovascular-related microRNAs elicited by extra virgin olive oil (EVOOs) containing different levels their own polyphenols.It is randomized, postprandial, parallel, double-blind study. Twelve healthy participants consumed 30 mL EVOO low (L-EVOO; 250 mg total phenols kg-1 oil), medium (M-EVOO; 500 and high (H-EVOO; 750 oil) enriched EVOOs. Postprandial plasma are analyzed real-time quantitative PCR. The results show that L-EVOO intake...