A5016688691- Foot and Ankle Surgery
- Tendon Structure and Treatment
- Bone Metabolism and Diseases
- Diabetic Foot Ulcer Assessment and Management
- Bone health and treatments
- Bone health and osteoporosis research
- Rheumatoid Arthritis Research and Therapies
- Orthopedic Surgery and Rehabilitation
- Lower Extremity Biomechanics and Pathologies
- Musculoskeletal synovial abnormalities and treatments
- Bone and Joint Diseases
- Nail Diseases and Treatments
- Vestibular and auditory disorders
- Cytokine Signaling Pathways and Interactions
- Spondyloarthritis Studies and Treatments
- Osteoarthritis Treatment and Mechanisms
- Sinusitis and nasal conditions
- Vitamin D Research Studies
- Hearing, Cochlea, Tinnitus, Genetics
- Traumatic Brain Injury and Neurovascular Disturbances
- Pharmacological Effects and Toxicity Studies
- Vitamin K Research Studies
- Autoimmune and Inflammatory Disorders Research
- Dupuytren's Contracture and Treatments
- Cerebral Venous Sinus Thrombosis
Osaka University
1991-2025
Osaka Minami Medical Center
2017-2024
Osaka Rosai Hospital
2022-2024
National Hospital Organization
2024
Nippon Medical School Hospital
2022-2023
Suita Municipal Hospital
2023
Life University
2015
Yamaguchi University
1981-1995
An epidemiological survey on vestibular neuronitis in Japan was conducted by means of a questionnaire filled major neuro-otology clinics (otolaryngologists) during 1988-1990 (3 years). The diagnostic criteria settled 1986 the Standardization Committee Society Equilibrium Research were applied. Gross analysis answers showed that i) there no sexual difference, ii) peak age distribution between 40-50 years, iii) about 30% all cases had common colds prior to disease, rate being highest among...
The impact of ROMO on the width anabolic windows and increase in BMD was reduced RA group compared to non-RA group, this reduction associated with correlations RA-related factors. To investigate effects romosozumab (ROMO) postmenopausal osteoporosis, without comorbid rheumatoid arthritis (RA). In retrospective, case-controlled, multicenter study, 171 patients who did not receive oral glucocorticoid, comprising 59 121 received uninterrupted treatment for 12 months. Propensity score matching...
To evaluate the impact of prior teriparatide (TPTD) treatment on effectiveness romosozumab (ROMO) in postmenopausal osteoporosis.
Estrogen deficiency following menopause increases receptor activator of nuclear factor-kappa B ligand (RANKL) expression in osteoblasts, thereby promoting osteoclast differentiation, and enhances T cell-derived tumor necrosis factor-alpha (TNFα) production, which induces sclerostin osteocytes, inhibiting bone formation. This study aimed to develop a novel uncoupling therapeutic agent for osteoporosis. We developed microglial healing peptide 1 with N-terminal acetylation C-terminal amidation...
Distal tibial oblique osteotomy (DTOO) has traditionally been contraindicated in patients with rheumatoid arthritis (RA). However, advances RA treatment, an increasing number of present resembling osteoarthritis (OA), suggesting DTOO as a potential option. This study aimed to compare mid-term clinical and radiographic outcomes between the OA RA. included 8 ankles 7 (Stage IIIa-IIIb, Takakura-Tanaka classification) 5 (equivalent Stage IIIa). Clinical (JSSF ankle/hindfoot scale, SAFE-Q),...
ABSTRACT Objective We aimed to identify the impact of rheumatoid factor (RF) or anti-cyclic citrullinated peptide antibody (ACPA) titers on retention biological disease-modifying antirheumatic drugs (bDMARDs) and Janus kinase inhibitors (JAKi) in patients with arthritis. Methods retrospectively analyzed 5312 courses bDMARDs JAKi from ANSWER cohort. To calculate hazard ratios (HRs) for treatment discontinuation, we used multivariate Cox proportional hazards modeling, adjusted potential...
Background: Arthrodesis of the first metatarsophalangeal (MTP) joint has been recommended for severe hallux valgus deformity in patients with rheumatoid arthritis (RA). However, progress medical treatment RA, preservation surgery recently performed. The aim this study was to investigate clinical and radiographic outcomes modified Scarf osteotomy medial capsule interposition RA cases including destruction MTP evaluate risk factors recurrence. Methods: A retrospective observational 76 (60...
Objectives: Advances in drug therapy for rheumatoid arthritis (RA) have been encouraging us to preserve the metatarsopharangeal (MTP) joint correction of forefoot deformities, and original metatarsal shortening offset osteotomy was recommended as one conventional surgical options deformities RA cases. The objective this study evaluate short- mid-term outcomes modified osteotomy. Methods: A retrospective observational completed 80 cases (mean follow-up period: 3.2 years) who underwent Both...
Objectives: To clarify the difference of patient-based outcome between joint-preserving arthroplasty and resection-replacement in forefoot surgery for patients with rheumatoid arthritis (RA). Methods: A total 63 feet 49 RA who underwent were asked to answer pre-operative post-operative self-administered foot evaluation questionnaire (SAFE-Q). Patients treated either (1) metatarsal head (28 feet, mean age 63.8 years, follow-up 4.2 DAS28-CRP 2.2) or (2) metatarsophalangeal (35 63.1 3.6 2.1) at...
Outcomes after total ankle arthroplasty (TAA) combined with additive techniques (augmentation of bone strength, control soft-tissue balance, adjustment the loading axis) for treatment rheumatoid arthritis were evaluated intermediate to long-term follow-up. The influences biologic on outcomes TAA also evaluated.We performed a retrospective observational study involving 50 ankles (44 patients) that underwent arthritis. mean duration follow-up was 7.1 years. Clinical use Japanese Society...
Objectives: Tocilizumab (TCZ) shows good retention in patients with rheumatoid arthritis (RA), but no previous reports demonstrated hopeful treatment options against inadequate response to TCZ. Tacrolimus (TAC) has proved show efficacy tumor necrosis factor alpha inhibitors, yet its add-on effects on TCZ remain unknown. Methods: Twenty RA (17 women, age 58.6 years, disease duration 12.1 prior 2.6 18 intravenous [8 mg/kg/month] and 2 subcutaneous [324 mg/month] treatments, methotrexate 6.1...
Control of rheumatoid arthritis (RA) disease activity is an important factor related to the development hallux valgus (HV) deformity. Furthermore, if hindfoot remains and/or appears after HV surgery, affected foot at risk recurrence We experienced a case suggesting possibility that deformity appeared surgery because poor control RA activity, and recurred in very early period surgery.