Xiaofei Du

ORCID: 0000-0002-0071-8093
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About
Contact & Profiles
Research Areas
  • Genetic Neurodegenerative Diseases
  • Video Surveillance and Tracking Methods
  • Robotics and Sensor-Based Localization
  • Ion channel regulation and function
  • Mitochondrial Function and Pathology
  • Surgical Simulation and Training
  • Image Enhancement Techniques
  • Optical Imaging and Spectroscopy Techniques
  • Advanced Neural Network Applications
  • Photoacoustic and Ultrasonic Imaging
  • RNA Research and Splicing
  • Fire Detection and Safety Systems
  • Soft Robotics and Applications
  • Anatomy and Medical Technology
  • Human Pose and Action Recognition
  • Advanced MRI Techniques and Applications
  • Plant-Microbe Interactions and Immunity
  • Non-Invasive Vital Sign Monitoring
  • Advanced Image and Video Retrieval Techniques
  • Genetics and Neurodevelopmental Disorders
  • Advanced Vision and Imaging
  • Antibiotic Resistance in Bacteria
  • Medical Image Segmentation Techniques
  • Domain Adaptation and Few-Shot Learning
  • Vibrio bacteria research studies

South China Sea Institute Of Oceanology
2023-2025

Institute of Oceanology
2023-2025

Chinese Academy of Sciences
2023-2025

Northwest A&F University
2025

University of Chinese Academy of Sciences
2023-2025

Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
2023-2024

Sichuan University
2021-2024

Nanjing Institute of Technology
2024

Chengdu University
2024

University of Chicago
2013-2023

Instrument detection, pose estimation, and tracking in surgical videos are an important vision component for computer-assisted interventions. While significant advances have been made recent years, articulation detection is still a major challenge. In this paper, we propose deep neural network articulated multi-instrument 2-D which trained on detailed annotations of endoscopic microscopic data sets. Our model formed by fully convolutional detection-regression network. Joints associations...

10.1109/tmi.2017.2787672 article EN cc-by IEEE Transactions on Medical Imaging 2018-01-15

Person re-identification (Re-ID) aims at recognizing the same person from images taken across different cameras. To address this task, one typically requires a large amount labeled data for training an effective Re-ID model, which might not be practical real-world applications. alleviate limitation, we choose to exploit sufficient of pre-existing (auxiliary) dataset. By jointly considering such auxiliary dataset and interest (but without label information), our proposed adaptation network...

10.1109/cvprw.2018.00054 article EN 2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW) 2018-06-01

Surgical-tool joint detection from laparoscopic images is an important but challenging task in computer-assisted minimally invasive surgery. Illumination levels, variations background and the different number of tools field view, all pose difficulties to algorithm model training. Yet, such challenges could be potentially tackled by exploiting temporal information videos avoid per frame handling problem. In this letter, we propose a novel encoder-decoder architecture for surgical instrument...

10.1109/lra.2019.2917163 article EN IEEE Robotics and Automation Letters 2019-05-15

Despite a growing number of ion channel genes implicated in hereditary ataxia, it remains unclear how mutations lead to loss-of-function or death cerebellar neurons. Mutations the gene KCNMA1, encoding α-subunit BK have emerged as responsible for variety neurological phenotypes. We describe mutation (BKG354S) child with congenital and progressive ataxia cognitive impairment. The selectivity filter dramatically reduced single-channel conductance selectivity. BKG354S trafficked normally...

10.1073/pnas.1920008117 article EN Proceedings of the National Academy of Sciences 2020-03-04

Summary The plant hormone ethylene plays a critical role in fruit defense against Botrytis cinerea attack, but the underlying mechanisms remain poorly understood. Here, we showed that response factor SlERF.C1 acts as key regulator to trigger ethylene‐mediated B. tomato fruits without compromising ripening. Knockout of increased susceptibility with no effect on ripening process, while overexpression enhanced resistance. RNA‐Seq, transactivation assays, EMSA and ChIP‐qPCR results indicated...

10.1111/nph.19632 article EN New Phytologist 2024-02-25

Person re-identification (re-ID) aims at matching images of the same identity across camera views. Due to varying distances between cameras and persons interest, resolution mismatch can be expected, which would degrade person re-ID performance in real-world scenarios. To overcome this problem, we propose a novel generative adversarial network address cross-resolution re-ID, allowing query with resolutions. By advancing learning techniques, our proposed model learns resolution-invariant image...

10.1109/iccv.2019.00818 article EN 2021 IEEE/CVF International Conference on Computer Vision (ICCV) 2019-10-01

Person re-identification (re-ID) solves the task of matching images across cameras and is among research topics in vision community. Since query real-world scenarios might suffer from resolution loss, how to solve mismatch problem during person re-ID becomes a practical problem. Instead applying separate image super-resolution models, we propose novel network architecture Resolution Adaptation re-Identification Network (RAIN) cross-resolution re-ID. Advancing strategy adversarial learning,...

10.1609/aaai.v33i01.33018215 article EN Proceedings of the AAAI Conference on Artificial Intelligence 2019-07-17

The autosomal dominant spinocerebellar ataxias (SCAs) are a genetically heterogeneous group of disorders exhibiting cerebellar atrophy and Purkinje cell degeneration whose subtypes arise from 31 distinct genetic loci. Our previously published the locus for SCA26 on chromosome 19p13.3. In this study, we performed targeted deep sequencing critical interval in order to identify candidate causative variants individuals family. We identified single variant that co-segregates with disease...

10.1093/hmg/dds392 article EN Human Molecular Genetics 2012-09-21

Selective translational blockade of the CACNA1A second cistron using miRNAs may have potential for treating spinocerebellar ataxia type 6.

10.1126/scitranslmed.aaf5660 article EN Science Translational Medicine 2016-07-13

Robot-assisted laparoscopic prostatectomy (RALP) is a treatment for prostate cancer that involves complete or nerve sparing removal tissue contains cancer. After the bladder neck successively sutured directly with urethra. The procedure called urethrovesical anastomosis and one of most dexterity demanding tasks during RALP. Two suturing instruments pair needles are used in combination to perform running stitch anastomosis. While robotic provide enhanced anastomosis, it still highly...

10.1109/icra.2018.8461200 article EN 2018-05-01

Computer-assisted interventions for enhanced minimally invasive surgery (MIS) require tracking of the surgical instruments. Instrument is a challenging problem in both conventional and robotic-assisted MIS, but vision-based approaches are promising solution with minimal hardware integration requirements. However, methods suffer from drift, case occlusions, shadows fast motion, they can be subject to complete failure. In this paper, we develop 2D tracker based on Generalized Hough Transform...

10.1007/s11548-016-1393-4 article EN cc-by International Journal of Computer Assisted Radiology and Surgery 2016-04-02

Intraoperative segmentation and tracking of minimally invasive instruments is a prerequisite for computer- robotic-assisted surgery. Since additional hardware like systems or the robot encoders are cumbersome lack accuracy, surgical vision evolving as promising techniques to segment track using only endoscopic images. However, what missing so far common image data sets consistent evaluation benchmarking algorithms against each other. The paper presents comparative validation study different...

10.48550/arxiv.1805.02475 preprint EN other-oa arXiv (Cornell University) 2018-01-01

Horizontal gene transfer, facilitated by mobile genetic elements (MGEs), is an adaptive evolutionary process that contributes to the evolution of bacterial populations and infectious diseases. A variety MGEs not only can integrate into genome but also survive or even replicate like plasmids in cytoplasm, thus requiring precise complete removal for studying their strategies benefiting host cells. Existing methods MGE removal, such as homologous recombination-based deletion excisionase-based...

10.1128/aem.00095-24 article EN Applied and Environmental Microbiology 2024-03-18

ABSTRACT The Shewanella genus is widely recognized for its remarkable respiratory adaptability in anaerobic environments, exhibiting potential bioremediation and microbial fuel cell applications. However, the genetic manipulation of certain strains hindered by defense systems that limit their modification biotechnology processes. In this study, we present a systematic method predicting, mapping, functionally analyzing islands within bacterial genomes. We investigated genetically recalcitrant...

10.1128/aem.02499-24 article EN cc-by Applied and Environmental Microbiology 2025-03-21

Spinocerebellar ataxia type 6 (SCA6) belongs to the family of CAG/polyglutamine (polyQ)-dependent neurodegenerative disorders. SCA6 is caused by abnormal expansion in a CAG trinucleotide repeat within exon 47 CACNA1A, bicistronic gene that encodes α1A, P/Q-type calcium channel subunit and C-terminal protein, termed α1ACT. Expansion CAG/polyQ region CACNA1A occurs α1ACT leads ataxia. There are few animal models SCA6. Here, we describe generation characterization first Drosophila melanogaster...

10.1093/hmg/ddv174 article EN Human Molecular Genetics 2015-05-07

Context: Kruppel-like factor 15 (KLF15) is a newly discovered transcription that plays an important role in glucose homeostasis and lipid accumulation cells. We present evidence for KLF15 as transcriptional regulator of the human 17β-hydroxysteroid dehydrogenase type 5 gene (HSD17B5) its potential pathogenesis hyperandrogenism. Objective: The aim was to investigate molecular mechanism HSD17B5 regulation. Methods: Diverse biology techniques were used. Design Results: identified binding site...

10.1210/jc.2009-0139 article EN The Journal of Clinical Endocrinology & Metabolism 2009-04-15
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