- Natural Antidiabetic Agents Studies
- Essential Oils and Antimicrobial Activity
- Phytochemistry Medicinal Plant Applications
- Natural product bioactivities and synthesis
- Phytochemicals and Antioxidant Activities
- Phytochemistry and Biological Activities
- Oral microbiology and periodontitis research
- Dental Erosion and Treatment
- Dental materials and restorations
- Allelopathy and phytotoxic interactions
- Phytochemical compounds biological activities
- Weed Control and Herbicide Applications
- Dental Health and Care Utilization
- Ethnobotanical and Medicinal Plants Studies
- Plant tissue culture and regeneration
- Plant biochemistry and biosynthesis
- Retinoids in leukemia and cellular processes
- Phytochemistry and Bioactivity Studies
- Pomegranate: compositions and health benefits
- Plant Molecular Biology Research
- Seed and Plant Biochemistry
- Advanced Glycation End Products research
- Coconut Research and Applications
- Agricultural and Food Sciences
- Plant Gene Expression Analysis
Universidade Estadual Paulista (Unesp)
2014-2023
Universidade de São Paulo
1992-2019
Universidade Paulista
2008
Centro Universitário de Araraquara
1999
The leaves of Myrcia DC. ex Guill species are used in traditional medicine and also exploited commercially as herbal drugs for the treatment diabetes mellitus. present work aimed to assess qualitative quantitative profiles M. bella hydroalcoholic extract, due these uses, since existing legislation Brazil determines that a standard method must be developed order quality control raw plant materials. current study identified eleven known flavonoid-O-glycosides six acylated flavonoid derivatives...
Bauhinia ungulata is a plant used in Brazilian traditional medicine for the treatment of diabetes. Phytochemical studies revealed flavonoids and saccharide pinitol related to hypoglycemic activity species. To determine effects water deficit on ecophysiological parameter metabolite fingerprints B. ungulata, specimens were treated with following regimens under greenhouse conditions: daily watering (control), every 7 days (group 7D), 15 15D). Metabolite profiling plants subjected was determined...
Miconia is one of the largest genus Melastomataceae, with approximately 1,000 species. Studies aiming to describe diverse biological activities species have shown promising results, such as analgesic, antimicrobial and trypanocidal properties. M. albicans leaves were dried, powdered extracted afford chloroformic methanolic extracts. Total phenolic contents in extract determined according modified Folin-Ciocalteu method. The antioxidant activity was measured using AAPH DPPH radical assays....
Species of Myrcia are used by indigenous people and in traditional communities Brazil for the treatment Diabetes mellitus. We investigated hypoglycemic effect extract leaves bella diabetic mice. The chemical fingerprinting 70% EtOH characterized as main constituents flavonoid aglycones, flavonoid-O-glycosides, acylated flavonoid-O-glycosides derivatives quercetin myricetin. Mice were treated with saline or M. (300 600 mg/Kg b.w.) 14 days. Body weight water food intake measured every day....
The genus Miconia comprises ∼1000 species belonging to the Melastomataceae family. Several crude plant extracts from and their isolated compounds have shown biological activities, such as analgesic anti-neoplastic action; however, no studies concerning effects on DNA are available. present study aimed evaluate, in vivo, genotoxic mutagenic of four plants using comet assay micronucleus test. Their possible protective were also evaluated experiments associating with cyclophosphamide (CPA)....
This study evaluated the antibiofilm and anti-caries effects of an experimental mouth rinse containing aqueous extract Matricaria chamomilla L.Microcosm biofilm was produced on bovine enamel, from pooled human saliva mixed with McBain saliva, under 0.2 % sucrose exposure, for 5 days. The daily treated using (1 mL/1 min): Vochysia tucanorum Mart. (2.5 mg/mL); Myrcia bella Cambess. (1.25 L. (20 Malva sylvestris (Malvatricin® Plus-Daudt); 0.12 Chlorhexidine (PerioGard®-Palmolive, Positive...
Candida biofilms adhere to the internal surface of removable dentures, which is an etiological factor in pathogenesis denture stomatitis (DS). Adhesive materials are used at base maxillary complete dentures improve their retention and chewing qualities. This article reports antimicrobial activity enriched fractions Equisetum giganteum Punica granatum incorporated into a adhesive against C. albicans biofilm. The were induced on heat-cured acrylic resin specimens that previously treated with...
Equisetum giganteum L. ( E. ), Equisetaceae, commonly called “giant horsetail,” is an endemic plant of Central and South America used in traditional medicine as diuretic hemostatic urinary disorders inflammatory conditions among other applications. The chemical composition the extract EtOH 70% has shown a clear presence phenolic compounds derived from caffeic ferulic acids flavonoid heterosides quercitin kaempferol, addition to styrylpyrones. , mainly at highest concentrations, showed...
This study investigated the effects of herbal toothpaste on bacterial counts and enamel demineralization. Thirty-six bovine samples were exposed to a microcosm biofilm using human saliva McBain (0.2% sucrose) for 5 days at 37 °C first incubated anaerobically, then aerobically-capnophilically. The following experimental slurries (2 × 2 min/day) applied: (1) Vochysia tucanorum (10 mg/g); (2) Myrcia bella (5 (3) Matricaria chamomilla (80 (4) Myrrha propolis (commercial); (5) fluoride (F)...
Hymenaea courbaril has been used to treat different diseases, although its properties are yet be scientifically validated. The objective of this study was determine the cytotoxicity, genotoxicity, antigenotoxicity and antioxidant potentials hydroethanolic extract from H. seeds. Therefore, for cytotoxicity test an anti-melanoma assay performed in B16F10 strain cells. genotoxicity evaluated bone marrow cells (Permit number: 002/2010) mice, activity determined by DPPH total flavonoid content...
The objective of this study was to evaluate the pharmacological mechanisms involved in anti-inflammatory and antidiarrheal actions hydroalcoholic extract obtained from leaves Cissus sicyoides (HECS). effect evaluated by oral administration HECS against acute model edema induced xylene, action were analysed involvement arachidonic acid (AA) prostaglandin E₂ (PGE₂). observed we analyzed motility accumulation intestinal fluid. We also evaluating role opioid receptor, α₂ adrenergic muscarinic...
"Aroeira" [Myracrodruon urundeuva Allemão (Anacardiaceae)] is a tree whose leaves have been studied for therapeutic purposes in medicine and dentistry.The study chemically identifies the leaf extract of aroeira determines its effect on human gingival fibroblasts.An 80% methanol leave was obtained by maceration identified through flow-injection analysis-electrospray ionization-ion trap-tandem mass spectrometry (FIA-ESI-IT-MSn). Cytotoxicity aroeira's evaluated lineage fibroblasts. Adherent...
Environmental conditions influence specialized plant metabolism. However, many studies aiming to understand these modulations have been conducted with model plants and/or under controlled conditions, thus not reflecting the complex interaction between and environment. To fully grasp interactions, we investigated metabolism genetic diversity of a native in its natural We chose Myrcia bella due medicinal interest occurrence Brazilian savanna regions diverse climate soil conditions. An...
Water and nitrogen availability are two major environmental factors that can impair plant growth, when combined, their effects on performance be either intensified or reduced. The objective of this study was to analyze the influence responses Amaranthus cruentus ’s metabolism water stress. plants were cultivated in plastic pots filled with vermiculite, kept under greenhouse conditions, watered three times a week 70% full strength nitrogen-free Long Ashton solution, containing 1.97 9.88 kg N...
Several species of Bauhinia are used in traditional medicine for the treatment gastrointestinal diseases, diabetes, and inflammation, among other conditions. The aim this study was to investigate antiulcer effect a hydroalcoholic extract from leaves B. holophylla . chemical profile determined by HPLC-PAD-ESI-IT-MS. A dose-effect relation constructed using ethanol-induced gastric ulcer model male Wistar rats. Histological analyses studies antioxidant anti-inflammatory activities were...
The effects of UV-B radiation were studied in sunflower plants (Helianthus annuus L. cv. Catissol-01) growning greenhouse under natural photoperiod conditions. received approximately 0.60Wm-2 (control) or 4.0Wm-2 (+UV-B) for 7h d-1, centered around solar noon from 15 days after sowing. Compared to the control, exposed high 12 21 did not show any difference shoot dry matter, specific leaf weight absorbing compounds. Enhanced caused a significant inhibition photosynthesis (A) only first...
New compound isolated from methanolic extract the leaves of Paepalanthus argenteus var. (Bongard) Hensold was characterized as xeractinol, a new dihydroflavonol C-glucoside. The structure elucidated on basis extensive spectroscopic analysis (1D and 2D NMR, MS, HREIMS, IR UV). Ab initio electronic calculations support our proposal to molecular structure. herein may serve taxonomic marker subgenus Xeractis, because this flavonoid have not been reported in any other taxon Eriocaulaceae.
Phytotoxicity is the term used to describe toxic effect of chemical compounds on growth and development plants. Phytotoxic vary in their composition, may be found natural environments due biosynthesis active release (allelochemicals). These have potential as pesticides for control agricultural plagues. Therefore, this study aimed evaluate phytotoxic different extracts fractions Tridax procumbens, using pre post-emergence bioassays Lactuca sativa L. seeds mitotic index Allium cepa root cells....