Luiz Leonardo Saldanha

ORCID: 0000-0003-2454-067X
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About
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Research Areas
  • Essential Oils and Antimicrobial Activity
  • Natural Antidiabetic Agents Studies
  • Plant Pathogenic Bacteria Studies
  • Phytochemistry Medicinal Plant Applications
  • Allelopathy and phytotoxic interactions
  • Dental Erosion and Treatment
  • Oral microbiology and periodontitis research
  • Banana Cultivation and Research
  • Phytochemical compounds biological activities
  • Phytochemicals and Antioxidant Activities
  • Plant-Microbe Interactions and Immunity
  • Dental materials and restorations
  • Phytochemistry and Biological Activities
  • Weed Control and Herbicide Applications
  • Dental Health and Care Utilization
  • Natural product bioactivities and synthesis
  • Coconut Research and Applications
  • Fungal Biology and Applications
  • Pomegranate: compositions and health benefits
  • Insect Pest Control Strategies
  • Pharmacological Effects of Natural Compounds
  • Botany and Plant Ecology Studies
  • Plant Gene Expression Analysis
  • Papaya Research and Applications
  • Advanced Glycation End Products research

University of Zurich
2024

Universidade Estadual Paulista (Unesp)
2013-2023

University of Geneva
2020-2022

Universidade de São Paulo
2022

Agroscope
2022

HES-SO University of Applied Sciences and Arts Western Switzerland
2021

The leaves of Myrcia DC. ex Guill species are used in traditional medicine and also exploited commercially as herbal drugs for the treatment diabetes mellitus. present work aimed to assess qualitative quantitative profiles M. bella hydroalcoholic extract, due these uses, since existing legislation Brazil determines that a standard method must be developed order quality control raw plant materials. current study identified eleven known flavonoid-O-glycosides six acylated flavonoid derivatives...

10.3390/molecules18078402 article EN cc-by Molecules 2013-07-16

Bauhinia ungulata is a plant used in Brazilian traditional medicine for the treatment of diabetes. Phytochemical studies revealed flavonoids and saccharide pinitol related to hypoglycemic activity species. To determine effects water deficit on ecophysiological parameter metabolite fingerprints B. ungulata, specimens were treated with following regimens under greenhouse conditions: daily watering (control), every 7 days (group 7D), 15 15D). Metabolite profiling plants subjected was determined...

10.3390/metabo13030381 article EN cc-by Metabolites 2023-03-03

Species of Myrcia are used by indigenous people and in traditional communities Brazil for the treatment Diabetes mellitus. We investigated hypoglycemic effect extract leaves bella diabetic mice. The chemical fingerprinting 70% EtOH characterized as main constituents flavonoid aglycones, flavonoid-O-glycosides, acylated flavonoid-O-glycosides derivatives quercetin myricetin. Mice were treated with saline or M. (300 600 mg/Kg b.w.) 14 days. Body weight water food intake measured every day....

10.1155/2014/543606 article EN cc-by Evidence-based Complementary and Alternative Medicine 2014-01-01

This study evaluated the antibiofilm and anti-caries effects of an experimental mouth rinse containing aqueous extract Matricaria chamomilla L.Microcosm biofilm was produced on bovine enamel, from pooled human saliva mixed with McBain saliva, under 0.2 % sucrose exposure, for 5 days. The daily treated using (1 mL/1 min): Vochysia tucanorum Mart. (2.5 mg/mL); Myrcia bella Cambess. (1.25 L. (20 Malva sylvestris (Malvatricin® Plus-Daudt); 0.12 Chlorhexidine (PerioGard®-Palmolive, Positive...

10.1016/j.jdent.2020.103415 article EN publisher-specific-oa Journal of Dentistry 2020-06-24

Equisetum giganteum L. ( E. ), Equisetaceae, commonly called “giant horsetail,” is an endemic plant of Central and South America used in traditional medicine as diuretic hemostatic urinary disorders inflammatory conditions among other applications. The chemical composition the extract EtOH 70% has shown a clear presence phenolic compounds derived from caffeic ferulic acids flavonoid heterosides quercitin kaempferol, addition to styrylpyrones. , mainly at highest concentrations, showed...

10.1155/2015/939625 article EN Evidence-based Complementary and Alternative Medicine 2015-01-01

Candida biofilms adhere to the internal surface of removable dentures, which is an etiological factor in pathogenesis denture stomatitis (DS). Adhesive materials are used at base maxillary complete dentures improve their retention and chewing qualities. This article reports antimicrobial activity enriched fractions Equisetum giganteum Punica granatum incorporated into a adhesive against C. albicans biofilm. The were induced on heat-cured acrylic resin specimens that previously treated with...

10.1080/08927014.2017.1407408 article EN Biofouling 2017-12-18

This study investigated the effects of herbal toothpaste on bacterial counts and enamel demineralization. Thirty-six bovine samples were exposed to a microcosm biofilm using human saliva McBain (0.2% sucrose) for 5 days at 37 °C first incubated anaerobically, then aerobically-capnophilically. The following experimental slurries (2 × 2 min/day) applied: (1) Vochysia tucanorum (10 mg/g); (2) Myrcia bella (5 (3) Matricaria chamomilla (80 (4) Myrrha propolis (commercial); (5) fluoride (F)...

10.3390/antibiotics11030414 article EN cc-by Antibiotics 2022-03-19

Hymenaea courbaril has been used to treat different diseases, although its properties are yet be scientifically validated. The objective of this study was determine the cytotoxicity, genotoxicity, antigenotoxicity and antioxidant potentials hydroethanolic extract from H. seeds. Therefore, for cytotoxicity test an anti-melanoma assay performed in B16F10 strain cells. genotoxicity evaluated bone marrow cells (Permit number: 002/2010) mice, activity determined by DPPH total flavonoid content...

10.1590/0001-3765201920180446 article EN cc-by Anais da Academia Brasileira de Ciências 2019-01-01

The objective of this study was to evaluate the pharmacological mechanisms involved in anti-inflammatory and antidiarrheal actions hydroalcoholic extract obtained from leaves Cissus sicyoides (HECS). effect evaluated by oral administration HECS against acute model edema induced xylene, action were analysed involvement arachidonic acid (AA) prostaglandin E₂ (PGE₂). observed we analyzed motility accumulation intestinal fluid. We also evaluating role opioid receptor, α₂ adrenergic muscarinic...

10.3390/ijms17020149 article EN International Journal of Molecular Sciences 2016-01-23

"Aroeira" [Myracrodruon urundeuva Allemão (Anacardiaceae)] is a tree whose leaves have been studied for therapeutic purposes in medicine and dentistry.The study chemically identifies the leaf extract of aroeira determines its effect on human gingival fibroblasts.An 80% methanol leave was obtained by maceration identified through flow-injection analysis-electrospray ionization-ion trap-tandem mass spectrometry (FIA-ESI-IT-MSn). Cytotoxicity aroeira's evaluated lineage fibroblasts. Adherent...

10.1080/13880209.2016.1182555 article EN Pharmaceutical Biology 2016-05-26

Environmental conditions influence specialized plant metabolism. However, many studies aiming to understand these modulations have been conducted with model plants and/or under controlled conditions, thus not reflecting the complex interaction between and environment. To fully grasp interactions, we investigated metabolism genetic diversity of a native in its natural We chose Myrcia bella due medicinal interest occurrence Brazilian savanna regions diverse climate soil conditions. An...

10.3390/molecules25122954 article EN cc-by Molecules 2020-06-26

Water and nitrogen availability are two major environmental factors that can impair plant growth, when combined, their effects on performance be either intensified or reduced. The objective of this study was to analyze the influence responses Amaranthus cruentus ’s metabolism water stress. plants were cultivated in plastic pots filled with vermiculite, kept under greenhouse conditions, watered three times a week 70% full strength nitrogen-free Long Ashton solution, containing 1.97 9.88 kg N...

10.1371/journal.pone.0270849 article EN cc-by PLoS ONE 2022-07-06

Several species of Bauhinia are used in traditional medicine for the treatment gastrointestinal diseases, diabetes, and inflammation, among other conditions. The aim this study was to investigate antiulcer effect a hydroalcoholic extract from leaves B. holophylla . chemical profile determined by HPLC-PAD-ESI-IT-MS. A dose-effect relation constructed using ethanol-induced gastric ulcer model male Wistar rats. Histological analyses studies antioxidant anti-inflammatory activities were...

10.1155/2015/439506 article EN Evidence-based Complementary and Alternative Medicine 2015-01-01

Abstract Brazil is the biggest producer of sweet oranges and main exporter concentrated orange juice in world. Among diseases that affect citriculture, Asiatic citrus canker, caused by bacterial pathogen Xanthomonas citri, represents one most significant threats. The current Brazilian legislation regulating control canker no longer requires eradication affected trees states where incidence disease high. Instead, involves measures, including periodic preventative spraying copper compounds....

10.1002/mbo3.1104 article EN cc-by MicrobiologyOpen 2020-08-06

Phytotoxicity is the term used to describe toxic effect of chemical compounds on growth and development plants. Phytotoxic vary in their composition, may be found natural environments due biosynthesis active release (allelochemicals). These have potential as pesticides for control agricultural plagues. Therefore, this study aimed evaluate phytotoxic different extracts fractions Tridax procumbens, using pre post-emergence bioassays Lactuca sativa L. seeds mitotic index Allium cepa root cells....

10.1016/j.sajb.2015.05.032 article EN cc-by South African Journal of Botany 2015-08-14

Bauhinia L. species, including holophylla (Bong.) Steud. (Fabaceae), have traditionally been used to treat diabetes. is a complex botanical genus, and the indiscriminate use of diverse species reflected in experimental divergence their medicinal potential.The hypoglycaemic hypolipidaemic effects, molecular mechanism action phytochemical properties an authentic extract B. leaves were evaluated.A study 70% EtOH was performed using FIA-ESI-IT-MS/MSn HPLC-PAD-ESI-IT-MS. The (200 or 400 mg/kg...

10.1080/13880209.2019.1599962 article EN cc-by Pharmaceutical Biology 2019-01-01

The deciduous plant Copaifera langsdorffii contains important medicinal compounds which may also be allelopathic and inhibitory to growth. species is endemic the Brazilian Cerrado where there pronounced climatic seasonality. In this study we demonstrate capacity of extracts from leaves C. pre-purified fractions extract. Analysis by HPLC-PAD-ESI-MS confirmed presence quercetin-3-O-α-rhamnoside kaempferol-3-O-α-rhamnoside as major components, well phenolic acid derivatives gallic acid. samples...

10.1590/0102-33062015abb0296 article EN cc-by Acta Botanica Brasilica 2016-03-15

Bauhinia holophylla leaves, also known as "pata-de-vaca", are traditionally used in Brazil to treat diabetes. Although the hypoglycemic activity of this medicinal plant has already been described, active compounds responsible for have not yet identified. To rapidly obtain two fractions large amounts compatible with further vivo assay, hydroalcoholic extract B. leaves was fractionated by Vacuum Liquid Chromatography and then purified medium pressure liquid chromatography combined an Glucose...

10.1371/journal.pone.0258016 article EN cc-by PLoS ONE 2021-09-24

Among the numerous plant species occurring in Cerrado, Ouratea spectabilis stands out because of lack that grow beneath its canopy. Therefore, this study aimed to evaluate phytotoxic potential different extracts and fractions hydroethanolic extract from leaves O. through laboratory bioassays pre-and post-emergence seeds Lactuca sativa L., determination mitotic index root cells Allium cepa antioxidant activity phytochemical screening classes present ethyl acetate fractions. It was possible...

10.1016/j.sajb.2014.10.002 article EN cc-by South African Journal of Botany 2014-11-01
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