A5112182093- Calcium signaling and nucleotide metabolism
- Neuroblastoma Research and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Genital Health and Disease
- Neuroendocrine Tumor Research Advances
- Sexual Differentiation and Disorders
- Urological Disorders and Treatments
- Cancer, Hypoxia, and Metabolism
- Radiomics and Machine Learning in Medical Imaging
- Pancreatic and Hepatic Oncology Research
- Advanced biosensing and bioanalysis techniques
- Signaling Pathways in Disease
- Frailty in Older Adults
- Urologic and reproductive health conditions
- Adrenal and Paraganglionic Tumors
- Occupational and environmental lung diseases
- Colorectal and Anal Carcinomas
- BRCA gene mutations in cancer
- Cardiac tumors and thrombi
- Ion Channels and Receptors
- Testicular diseases and treatments
- Hormonal Regulation and Hypertension
- Head and Neck Cancer Studies
- Tuberculosis Research and Epidemiology
University of Genoa
2011-2015
Hospital de Clínicas "José de San Martín"
1983-2011
University of Buenos Aires
1983-1996
Objective: We evaluated the efficacy of fine needle aspiration cytology (FNAC) thyroid in a series 5469 lesions with histological control and studied causes of, possibility reducing limitations method. Methods: FNAC was always performed by pathologist under guidance clinician, using 22‐gauge needle. Generally two aspirations were carried out, usually four slides obtained for each nodule; they then stained May–Grünwald–Giemsa Papanicolaou. The cytological diagnoses classified groups:...
Immunoglobulin (Ig) isotype diversification by class switch recombination (CSR) is an essential process for mounting a protective humoral immune response.Ig CSR deficiencies in humans can result from intrinsic B cell defect; however, most of these are still molecularly undefined and diagnosed as common variable immunodeficiency (CVID).Here, we show that extracellular adenosine critically contributes to human naive IgM memory cells.In cells, coordinate stimulation receptor toll-like receptors...
Background Neuroblastoma (NB) is a severe pediatric tumor originating from neural crest derivatives and accounting for 15% of childhood cancer mortality. The heterogeneous complex genetic etiology has been confirmed with the identification mutations in two genes, encoding receptor tyrosine kinase Anaplastic Lymphoma Kinase (ALK) transcription factor Paired-like Homeobox 2B (PHOX2B), limited proportion NB patients. Interestingly, these genes are overexpressed great majority primary samples...
The hormone abscisic acid (ABA) is a small molecule involved in pivotal physiological functions higher plants. Recently, ABA has been also identified as an endogenous mammals, regulating different cell including inflammatory processes, stem expansion, insulin release, and glucose uptake. Aptamers are short, single-stranded (ss) oligonucleotidesable to recognize target molecules with high affinity. size of the represented challenge for aptamer development aim this study was develop specific...
Fiberoptic bronchoscopy was useful for the diagnosis of 7 9 pulmonary lymphomas (5 primary lung lymphomas, 4 involvement in systemic disease). Radiologic and endoscopic findings were variable. The importance immunohistochemical markers successful is emphasized
Natural killer (NK) cells are capable of lysing certain tumor in vitro. We investigated whether the percentage NK (NK%) serous effusions has any relation with presence malignant cells. Fresh were routinely processed, and a portion them was submitted for lymphocyte immunophenotyping, using flow cytometer. Fifty-one fluids (15 peritoneal, 36 pleural), from 47 patients analyzed. Thirty-two cases negative 19 positive neoplastic cells: there 13 adenocarcinomas, 2 mesotheliomas (MM), 3 lymphomas...