Nicolas Adam

ORCID: 0000-0002-0933-7705
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About
Contact & Profiles
Research Areas
  • Respiratory Support and Mechanisms
  • Intensive Care Unit Cognitive Disorders
  • Airway Management and Intubation Techniques
  • Transplantation: Methods and Outcomes
  • Traumatic Brain Injury Research
  • Cardiac Arrest and Resuscitation
  • Ultrasound in Clinical Applications
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Anesthesia and Sedative Agents
  • S100 Proteins and Annexins
  • Epilepsy research and treatment
  • EEG and Brain-Computer Interfaces
  • Legionella and Acanthamoeba research
  • Orthopaedic implants and arthroplasty
  • Renal Transplantation Outcomes and Treatments
  • Viral Infections and Immunology Research
  • Esophageal and GI Pathology
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Advanced Neuroimaging Techniques and Applications
  • Cellular transport and secretion
  • Molecular Biology Techniques and Applications
  • Foreign Body Medical Cases
  • RNA regulation and disease
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Hemostasis and retained surgical items

Sorbonne Université
2014-2024

Pitié-Salpêtrière Hospital
2017-2024

Groupe de recherche clinique en anesthésie réanimation médecine périopératoire
2024

Assistance Publique – Hôpitaux de Paris
2013-2024

Laboratoire d'Aérologie
2019

Paris Cardiovascular Research Center
2019

Institut National des Sciences Appliquées de Lyon
2018

Inserm
2017

Collège de France
2017

Université Paris Sciences et Lettres
2017

Abstract Astrocytes send out long processes that are terminated by endfeet at the vascular surface and regulate functions as well homeostasis interface. To date, astroglial mechanisms underlying these have been poorly addressed. Here we demonstrate a subset of messenger RNAs is distributed in astrocyte endfeet. We identified, among this transcriptome, pool bound to ribosomes, endfeetome, primarily encodes for secreted membrane proteins. detected nascent protein synthesis Finally, determined...

10.1038/celldisc.2017.5 article EN cc-by Cell Discovery 2017-03-28

Postextubation respiratory failure (PRF) frequently complicates weaning from mechanical ventilation and may increase morbidity/mortality. Noninvasive (NIV) alternating with high-flow nasal oxygen (HFNO) prevent PRF. Ventilated patients without chronic obstructive pulmonary disease (COPD) at high-risk of PRF defined as a lung ultrasound score (LUS) ≥ 14 assessed during the spontaneous breathing trial, were included in French-Chinese randomised controlled trial. was by 2 among following signs:...

10.1186/s13054-024-05166-w article EN cc-by-nc-nd Critical Care 2024-11-26

<b>Background:</b> High-flow nasal cannula (HFNC) has been shown to induce lung recruitment and reduce respiratory muscle loading. <b>Aims Objectives:</b> To compare the effects of HFNC <i>vs</i> noninvasive ventilation (NIV) on re-aeration diaphragm function in patients with acute failure (ARF). <b>Methods:</b> Twenty spontaneously breathing were prospectively studied. They received three 60-minutes trials (60L/min), NIV standard oxygen (O<sub>2</sub>) applied random order. After each...

10.1183/1393003.congress-2017.pa2180 article EN 2017-09-01
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