Jiapeng Xu
- Bioactive Compounds in Plants
- Phytochemicals and Antioxidant Activities
- Artificial Intelligence in Healthcare and Education
- Phytochemical compounds biological activities
- Machine Learning in Healthcare
- Topic Modeling
- Inflammatory mediators and NSAID effects
- COVID-19 diagnosis using AI
- Ferroptosis and cancer prognosis
- Helicobacter pylori-related gastroenterology studies
Stanford University
2024-2025
Yunnan Provincial Hospital of Traditional Chinese Medicine
2023
0. Abstract Background The integration of large language models (LLMs) in healthcare offers immense opportunity to streamline tasks, but also carries risks such as response accuracy and bias perpetration. To address this, we conducted a red-teaming exercise assess LLMs developed dataset clinically relevant scenarios for future teams use. Methods We convened 80 multi-disciplinary experts evaluate the performance popular across multiple medical scenarios. Teams composed clinicians, engineering...
Red teaming, the practice of adversarially exposing unexpected or undesired model behaviors, is critical towards improving equity and accuracy large language models, but non-model creator-affiliated red teaming scant in healthcare. We convened teams clinicians, medical engineering students, technical professionals (80 participants total) to stress-test models with real-world clinical cases categorize inappropriate responses along axes safety, privacy, hallucinations/accuracy, bias. Six...
Orthosiphon stamineus Benth is a dietary supplement and traditional Chinese herb with widespread clinical applications, but comprehensive understanding of its active compounds polypharmacological mechanisms lacking. This study aimed to systematically investigate the natural molecular O. via network pharmacology.Information on from was collected literature retrieval, while physicochemical properties drug-likeness were evaluated using SwissADME. Protein targets screened SwissTargetPrediction,...
Abstract Background Orthosiphon stamineus Benth. was a dietary supplement or traditional folk herb with widespread clinical application, but it lack of comprehensive understanding its active ingredients and polypharmacological mechanisms. The aim this work to systematically study natural compounds the molecular mechanisms O. via network pharmacology. Methods Compounds from were collected by literature retrieval evaluated SwissADME physicochemical property (ADMET model) likelihood for...
Abstract Background: Helicobacter pylori ( H. ) infection is the most common risk factor for gastric cancer (GC). The effect of antioxidase manganese superoxide dismutase (SOD2 or MnSOD) in tumorigenesis remains unclear. Methods: We explored molecular and mechanical links between , inflammation, SOD2 GC. RNA sequencing was conducted to identify differentially expressed mRNAs -infected uninfected cells. putative role response investigated vitro vivo . Results: upregulated GC patients with...