A5101792960- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Hepatitis B Virus Studies
- Food Safety and Hygiene
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Hepatitis C virus research
- Drug-Induced Hepatotoxicity and Protection
- Clostridium difficile and Clostridium perfringens research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Liver Disease Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Pneumonia and Respiratory Infections
- Tuberculosis Research and Epidemiology
- Fungal Infections and Studies
- Urological Disorders and Treatments
- Animal Disease Management and Epidemiology
- Pharmacovigilance and Adverse Drug Reactions
- Antifungal resistance and susceptibility
- Pharmaceutical industry and healthcare
- Bioactive Compounds and Antitumor Agents
- Nigella sativa pharmacological applications
- Magnetic Properties and Synthesis of Ferrites
- Sepsis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Complement system in diseases
Pfizer (United States)
2006-2024
Karachi Medical and Dental College
2024
Geisinger Medical Center
2014-2017
University of Veterinary and Animal Sciences
2014
Michigan State University
2006-2010
Aga Khan University
2005
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). The authors retract the above paper due to: 1) conflict of interest among authors; and 2) addition coauthor Dr. Muhammad Younus without his knowledge or permission. apologize for these two grave mistakes.
This study evaluated the independent contribution of voriconazole to development squamous cell carcinoma (SCC) in lung transplant recipients, by attempting account for important confounding factors, particularly immunosuppression. international, multicenter, retrospective, cohort included adult patients who underwent transplantation during 2005-2008. Cox regression analysis was used assess effects and other azoles, analyzed as time-dependent variables, on risk developing biopsy-confirmed...
Abstract Background The magnitude of chronic infection with hepatitis B virus (HBV) varies substantially between the countries. A better understanding incidence and/ or prevalence HBV and associated risk factors provides insight into transmission this in community. purpose investigation was to estimate identify HBV, as assessed by surface antigen (HBsAg) positivity, asymptomatic volunteer male blood donors Karachi, Pakistan. Methods Consecutive donations made at two large banks January 1,...
Summary. The objectives of this study were to assess the proportion hepatitis C virus (HCV) reactors and identify risk factors associated with HCV infection in volunteer blood donors Karachi, Pakistan. Between 1 January 1998 31 December 2002, consecutive donations tested at two banks used sero‐reactors donors. To evaluate potential factors, a case‐control design was implemented select cases controls between 15 October 2001 March 2002. overall seroprevalence these 1.8% (6349/35 1309). Trend...
Abstract Background: The majority of U.S. disease surveillance systems contain incomplete information regarding socioeconomic status (SES) indicators like household or family income and educational attainment in case reports, which reduces the usefulness data for these parameters. We investigated association between select SES attributes at neighborhood level Salmonella infections three most populated counties Michigan using a geographic system. Methods: obtained on income, education, race...
Salmonellosis is largely a major foodborne disease. However, contact with animals particularly reptiles, has been increasingly recognized as risk factor for Salmonella infection among children. The factors salmonellosis in Michigan children have not assessed. Therefore, we evaluated the association between infections and aged ≤ 10 years by conducting population-based case-control study. A total of 123 laboratory-confirmed 139 control children, who had experienced symptoms gastrointestinal...
ABSTRACT Purpose Risk Evaluation and Mitigation Strategies (REMS) include various mechanisms to enhance safe use of medications, including a patient medication guide (MG) that provides key information regarding the potential risks associated with medication. To evaluate effectiveness varenicline MG as REMS tool for educating patients, we undertook survey among patients who were dispensed varenicline. Methods Varenicline recipients within Optum Research Database, large U.S. administrative...
Recent epidemiological studies identifying an association between some classes of gastric acid suppressants and Clostridium difficile colitis community-acquired pneumonia prompted our analysis. Our objective was to retrospectively apply data mining algorithms (DMAs) the Food Drug Administration (FDA) drug safety database see if they might have directed/redirected attention reported suppressive drugs with C. pneumonia, prior published findings that supported association.Two statistical DMAs,...
Abstract Background Limited real-world data from routine clinical care are available on the safety and effectiveness of treatment with taliglucerase alfa in patients Gaucher disease (GD). Methods Taliglucerase Alfa Surveillance (TALIAS), a multinational prospective Drug Registry GD, was established to evaluate long-term (primary objective) (secondary alfa. We present an interim analysis collected over 5-year period September 2013 January 2019. Results A total 106 GD (15.1% children aged <...
This paper presents a review of security vulnerabilities found in IEEE 802.16e that are still unaddressed. In particular leading to Denial Service (DoS) attacks on based network discussed detail. These include unprotected Network entry, unencrypted management communication, frames and weak key sharing mechanism multicast broadcast operations. Moreover new vulnerability regarding Reset-Command (RES-CMD) message is identified which can lead DoS attack client machines. also meticulous...
Abstract Background Liver disorders are important adverse effects associated with antifungal drug treatment. However, the accuracy of Clinical International Classification Diseases (ICD)-10 codes in identifying liver for register based research is not well-established. This study aimed to determine positive predictive value (PPV) ICD-10 patients toxic disease, hepatic failure, and jaundice among systemic Methods Data from Swedish Prescribed Drug Register National Patient were utilized...
Abstract Pediatric-specific safety data are required during development of pharmaceutical agents. Retrospective studies can leverage real-world to assess and effectiveness in children where prospective, controlled not feasible. A retrospective cohort study combined from Pediatric Health Information Systems (PHIS) medical records evaluate the piperacillin/tazobactam (P/T) pediatric patients with hospital-acquired pneumonia (HAP). After identifying 407 diagnosed HAP receiving P/T (n=140) or...
Salmonella Enteritidis is a major cause of foodborne disease worldwide. In the United States, this serotype has been associated with significant morbidity and mortality accounting for about 17% all human infections. Data on risk factors serotype-specific infections have not reported in Michigan before. We carried out study using surveillance data to identify high-risk groups regions S. infection Michigan. Results may be used develop better control prevention measures against common pathogen....
Abstract Background Infections with Salmonella serotypes continue to be a significant global public health problem. In addition contaminated foods, several other sources contribute infections serotypes. We have assessed the role of socioeconomic factors, exposure food, and environmental in etiology non-typhoidal Michigan children. Findings A case-control study among children aged ≤ 10 years was conducted. total 123 cases laboratory-confirmed 139 control children, who had not experienced...
A recent literature review linked norepinephrinergic stimulation to alterations in cyclic adenosine monophosphate (cAMP)-mediated signaling cardiac myocytes and suggested that this might contribute the pathological mechanisms lead chamber enlargement hypocontractility, which are seen dilated cardiomyopathy. This accompanies a large body of linking sympathetic outflow activation early heart failure with progressive myocyte deterioration. As mode action number antidepressants involves...