- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Function and Risk Factors
- Renal and Vascular Pathologies
- Venous Thromboembolism Diagnosis and Management
- Acute Ischemic Stroke Management
- Gout, Hyperuricemia, Uric Acid
- Cardiac Valve Diseases and Treatments
- Cardiovascular Disease and Adiposity
- Heart Failure Treatment and Management
- Radiomics and Machine Learning in Medical Imaging
- Chronic Kidney Disease and Diabetes
- Advanced X-ray and CT Imaging
- Acute Kidney Injury Research
- Atrial Fibrillation Management and Outcomes
- Biomarkers in Disease Mechanisms
- Peripheral Artery Disease Management
- Blood Pressure and Hypertension Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac tumors and thrombi
- Atherosclerosis and Cardiovascular Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Metallurgical Processes and Thermodynamics
New Tokyo Hospital
2019-2025
Fukuoka Tokushukai Hospital
2012-2023
Nozaki Tokushukai Hospital
2012-2023
Kawasaki Medical School
2016-2018
Background Despite its recommendation by the current guidelines, role of long-term oral beta-blocker therapy has never been evaluated randomized trials in uncomplicated ST-segment elevation myocardial infarction (STEMI) patients without heart failure, left ventricular dysfunction or arrhythmia who underwent primary percutaneous coronary intervention (PCI). Methods and results In a multi-center, open-label, controlled trial, STEMI with successful PCI within 24 hours from onset ejection...
Background The relationship between gut microbiota and in vivo coronary plaque characteristics has not been reported. This study was conducted to investigate the patients with artery disease. Methods Results Patients who underwent both optical coherence tomography intravascular ultrasound imaging provided stool blood specimens were included. composition of evaluated using 16S rRNA sequencing. A total 55 At genus level, 2 bacteria associated presence thin-cap fibroatheroma, 9 smaller fibrous...
Background: There are little available data about the impact of geriatric nutritional risk index (GNRI) on clinical outcomes following endovascular therapy (EVT) in chronic limb-threatening ischemia (CLTI) regarding severities renal dysfunction (RD). Aims: The aim this study is to evaluate GNRI EVT CLTI RD. Methods: We enrolled 705 consecutive cases treated with between January 2010 and December 2019 at our hospital. admission was calculated as follows: [14.89 × albumin (g/dL)] + [41.7 (body...
Aim: Multiple risk factor syndrome is a target for the prevention of coronary artery disease (CAD). A cluster multiple factors, such as hypertension, glucose intolerance, and/or dyslipidemia, encountered in Japanese without and with excess visceral fat. The present study investigated relationship between accumulation CAD fat accumulation.Methods: subjects comprised 257 suspected (males/females= 153/ 104), who underwent 64-row multislice computed tomography (CT) angiography area (VFA)...
Erythropoietin (EPO) has antiapoptotic and tissue-protective effects, but previous clinical studies using high-dose EPO have not shown cardioprotective probably because of platelet activation a lack knowledge regarding the optimal dose. In contrast, small pilot study low-dose improvement in left ventricular function without adverse cardiovascular events.Methods Results:We performed multicenter (25 hospitals), prospective, randomized, double-blind, placebo-controlled, dose-finding to clarify...
The anti-inflammatory effects of the xanthine oxidase inhibitor, febuxostat, a urate-lowering agent, have been reported in animal studies. However, therapy and its associated cardiovascular protective not fully determined actual clinical practice. This study aimed to investigate effect febuxostat on white blood cell (WBC) count patients with asymptomatic hyperuricemia assess for potential correlations between changes WBC inflammatory biomarkers atherosclerosis this patient population.
To investigate the relationship between eccentric calcification of aortic valve and transcatheter heart (THV) distortion impact THV on echo parameters clinical outcomes.The effects were not fully understood.Patients with symptomatic severe stenosis who undergoing implantation enrolled. Patients underwent preprocedural, postprocedural multislice computed tomography (MSCT), follow-up transthoracic echocardiogram (TTE). Delta calcium score (ΔCS) is defined as difference maximum minimal scores...
The extraaortic-valvular cardiac damage (EVCD) Stage has shown potential for risk stratification patients with aortic stenosis (AS). This study aimed to examine the usefulness of EVCD in moderate AS and reduced left ventricular ejection fraction (LVEF).
Abstract Background Multi-slice computed tomography (CT) is useful for the non-invasive detection and quantification of coronary calcium burden. However, a definitive parameter based on CT imaging predicting need debulking devices, such as rotational atherectomy (RA) orbital (OAS), has yet to be established. Purpose We aimed develop calcification risk score using cardiac predict use devices during intervention. Methods In this retrospective, multi-center, observational study in Japan,...
Abstract Background Provisional single stenting strategy (PSS) is a default for percutaneous coronary intervention (PCI) of unprotected left main distal bifurcation lesions (ULMD). Previous study reported that angle change (BAC) between end diastole and systole was associated with outcomes after PCI double stent (DSS) ULMD. However, there are no data comparing PSS versus DSS according the degree BAC. Objectives We evaluated true ULMD small large Methods identified 566 patients underwent in...
Attenuated plaque on intravascular ultrasound (IVUS) and low attenuation computed tomography angiography (CTA) are associated with no-reflow phenomenon during percutaneous coronary intervention (PCI). However, evaluation by a single modality has been unable to satisfactorily predict this phenomenon. We investigated whether the combination of IVUS CTA findings can ameliorate predictive potential for after stent implantation PCI in stable artery disease (CAD). A total 988 lesions 707 CAD...