- Diet and metabolism studies
- Biochemical Analysis and Sensing Techniques
- Regulation of Appetite and Obesity
- Tryptophan and brain disorders
- Adipose Tissue and Metabolism
- Treatment of Major Depression
- Ginger and Zingiberaceae research
- Obesity, Physical Activity, Diet
- COVID-19 and Mental Health
- Digital Mental Health Interventions
- Mental Health Research Topics
- Diet, Metabolism, and Disease
- Birth, Development, and Health
- Metabolism and Genetic Disorders
- Eating Disorders and Behaviors
- Schizophrenia research and treatment
- Stress Responses and Cortisol
- Muscle metabolism and nutrition
- Temporomandibular Joint Disorders
- Orthodontics and Dentofacial Orthopedics
- Bipolar Disorder and Treatment
- Agricultural and Food Sciences
- Neuroinflammation and Neurodegeneration Mechanisms
- Occupational Health and Burnout
- Animal Genetics and Reproduction
Hospital de Clínicas de Porto Alegre
2020-2025
Universidade Federal do Rio Grande do Sul
2015-2025
Universidade Federal do Rio Grande
2023
Instituto Nacional de Ciência e Tecnologia Translacional em Medicina
2023
Universidade Federal do Pampa
2021
Universidade Feevale
2021
Hospital de Clínicas
2020
Australian Regenerative Medicine Institute
2016-2019
Monash University
2016-2019
Hypertension is associated with platelet alterations that could contribute to the development of cardiovascular complications. Several studies have reported antiplatelet aggregation properties ginger (Zingiber officinale) and turmeric (Curcuma longa) limited scientific basis. Hence, this study assessed effect dietary supplementation these rhizomes on ectonucleotidase adenosine deaminase (ADA) activities in Nω-nitro-l-arginine methyl ester hydrochloride (l-NAME) induced hypertensive rats....
The present study investigated the effects of a 6‐week swimming training on blood pressure, nitric oxide (NO) levels and oxidative stress parameters such as protein lipid oxidation, antioxidant enzyme activity endogenous non‐enzymatic content in kidney circulating fluids, well serum biochemical (cholesterol, triglycerides, urea creatinine) from Nω‐nitro‐L‐arginine methyl ester hydrochloride (L‐NAME)‐induced hypertension treated rats. Animals were divided into four groups ( n = 10): Control,...
Ginger and turmeric rhizomes are used in folk medicine for the treatment of several cerebrovascular diseases with limited scientific basis their action. Hence, this study, we investigate effects two Zingiberaceae varieties (ginger turmeric) on ectonucleotidases (NTPDase 5'-nucleotidase), adenosine deaminase (ADA) acetylcholinesterase (AChE) activities synaptosomes cerebral cortex from l-NAME induced hypertensive rats. The animals were divided into seven groups (n = 10): normotensive control...
Highlights•Crat in AgRP neurons helps nutrient replenishment as food is available after fasting•Crat maintain appropriate hepatic glucose production during facilitates peripheral substrate switching upon acute refeeding•Crat regulates protein expression and acetylation cells fasting refeedingSummaryAgRP control utilization partitioning conditions of energy deficit replenishment, although the molecular mechanism unknown. We examined whether carnitine acetyltransferase (Crat) affects...
Coronavirus disease 2019 (COVID-19) was declared a global pandemic early in 2020, followed by period during which governments imposed strict social distancing measures to slow transmission. However, most essential services remained open, and those working offices faced higher risk of infection compared at home. We compare the occurrence potential determinants mental health outcomes, functioning, quality life (QoL) subset sample Brazilian individuals who worked from home office first wave COVID-19.
Obesity affects a large number of people around the world and appears to be result changes in food intake, eating habits physical activity levels. Changes dietary patterns exercise are therefore strongly recommended treat obesity its complications. The present study tested hypothesis that metabolic produced by cafeteria diet can prevented with and/or exercise. A total fifty-six female Wistar rats underwent one five treatments: chow diet; followed plus exercise; duration experiment was 34...
Inflammation exerts a crucial pathogenic role in the development of hypertension. Hence, aim present study was to investigate effects ginger (<i>Zingiber officinale</i>) and turmeric (<i>Curcuma longa</i>) on enzyme activities purinergic cholinergic systems as well inflammatory cytokine levels N<i>ω</i>-nitro-L-arginine methyl ester hydrochloride-induced hypertensive rats. The rats were divided into seven groups (n = 10); 1–3 included normotensive control rats, (N<i>ω</i>-nitro-L-arginine...
In the present study, we investigated whether maternal exposure to a cafeteria diet affects metabolism and body composition of offspring such an has cumulative effect during lifetime offspring. Female rats were fed control (CON) or (CAF) from their own weaning At 21 d age, male divided into four groups by gestation after (CON-CON, CON-CAF, CAF-CON CAF-CAF). Blood was collected dams (after weaning) pups (at 30 120 age) decapitation. CAF had significantly greater weight adipose tissue higher...
The present study aimed to analyze the effects of sleep restriction (SR) during pregnancy in rats. following three groups were studied: home cage (HC pregnant females remained their cage), Sham (females placed tanks similar SR group but with sawdust) and submitted multiple platform method for 20 h per day from gestational days (GD) 14 20). Plasma corticosterone after 6 was not different among groups. However, relative adrenal weight higher compared HC group, which suggests possible stress...
The aim of this study was to test the hypothesis that treatment with orthodontic appliances evokes significant functional limitations and emotional stress, which can be detected by salivary biomarkers.Twenty subjects (10 men 10 women) who underwent were included in prospective study. Saliva sampled for detection alpha-amylase activity cortisol levels at three different times: before bracket placement (T0), 24 hours after archwire (T1), 30 days (T2). saliva electrolytes concentrations...
Ghrelin, an orexigenic gut-derived peptide, is gaining increasing attention due to its multifaceted role in a number of physiological functions, including reproduction. Ghrelin exists circulation primarily as des-acylated and acylated ghrelin. Des-acyl ghrelin, until recently considered be inactive form now known have independent functionality. However, the relative contribution acyl des-acyl ghrelin reproductive development function currently unknown. Here we used ghrelin-O-acyltransferase...
Psychiatric disorders are associated with more than 90% of reported suicide attempts worldwide, but few treatments have demonstrated a direct effect in reducing risk. Ketamine, originally an anesthetic, has been shown anti-suicide effects clinical trials designed to treat depression. However, changes at the biochemical level were assessed only protocols ketamine very limited sample sizes, particularly when subcutaneous route was considered. In addition, inflammatory and their correlation...
Previous studies have involved the "posterodorsal" amygdaloid area with control of food intake and development obesity in rats. Within this wide region, posterodorsal medial amygdala (MePD) has connections specific hypothalamic nuclei that increase feeding behavior modulate energy balance. Glutamate is major brain excitatory neurotransmitter, remarkably enhances centrally mediated consumption, abundantly found MePD. Here, it was studied effects saline (0.3 μL) glutamate (45 nM or 45 mM/0.3...
<title>Abstract</title> Background In Brazil, 57.5% of men and 62.6% women are considered overweight, highlighting obesity as a public health issue. Obesity increases the risk various chronic diseases, most people struggle to maintain weight loss in long term. The Transtheoretical Model is an approach that considers readiness for behavioral change, questionnaires like Process Change Questionnaire (P-Weight), Stages (S-Weight) have been developed assess these changes management. This study...
Aims: To evaluate the effect of caloric and non-caloric soft drink intake on food consumption, body weight composition, metabolic parameters in rats.Methods: Controlled experimental study which 30 male Wistar rats were divided into three groups given beverage ad libitum during 17 weeks. The as follows, according to offered food: Control group – standard chow water; Caloric chow, drink, Non-caloric water.Results: There was no statistical difference total energy intake, weight, fat deposition...
A dietoterapia é essencial para pacientes hospitalizados. O objetivo deste estudo foi avaliar a aceitabilidade das refeições do almoço de que receberam dietética Diabetes Mellitus (DM) e verificar aspectos podem interferir nesse consumo, como as estações ano. Estudo quantitativo descritivo avaliou o consumo da refeição dos DM em um período verão outro inverno no ano 2019. Os dados foram verificados frequências absolutas, porcentagens, médias, teste estatístico regressão logística com...