A5064988364- Health disparities and outcomes
- Global Health Care Issues
- Advanced Malware Detection Techniques
- Migration, Health and Trauma
- Spinal Cord Injury Research
- Trace Elements in Health
- Birth, Development, and Health
- Transcranial Magnetic Stimulation Studies
- Global Maternal and Child Health
- Climate Change and Health Impacts
- Software Engineering Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Traumatic Brain Injury Research
- Spam and Phishing Detection
- Spinal Hematomas and Complications
- Network Security and Intrusion Detection
- Nerve injury and regeneration
- Diabetic Foot Ulcer Assessment and Management
- Pituitary Gland Disorders and Treatments
- Selenium in Biological Systems
- Child Nutrition and Water Access
- Musculoskeletal pain and rehabilitation
- Growth Hormone and Insulin-like Growth Factors
- Pancreatic function and diabetes
- Menopause: Health Impacts and Treatments
Army Medical University
2025
Chongqing Medical University
2025
Second Affiliated Hospital of Chongqing Medical University
2025
Dalian Medical University
2025
Children's Hospital of Capital Institute of Pediatrics
2025
Jiangsu Vocational College of Medicine
2023-2024
Sichuan University
2017-2024
Soochow University
2022-2024
Second Affiliated Hospital of Soochow University
2022-2024
Jiangxi Agricultural University
2024
Spinal cord regeneration after a spinal injury (SCI) remains difficult challenge due to the complicated inflammatory microenvironment and neuronal damage at sites. In this study, retinoic acid (RA) curcumin (Cur) were co-loaded with bovine serum albumin (BSA) self-assembly obtain RA@BSA@Cur nanoparticles (NPs) for SCI treatment. Cur, as an antioxidant drug, facilitated reactive oxygen species (ROS) scavenging, decreased amount of factors secreted by macrophages, while RA could enhance...
Climate change is anticipated to influence heat-related mortality in the future. However, estimates of excess attributable future heat waves are subject large uncertainties and have not been projected under latest greenhouse gas emission scenarios.We estimated wave eastern United States (approximately 1,700 counties) two Representative Concentration Pathways (RCPs) investigated sources uncertainty.Using dynamically downscaled hourly temperature projections for 2057-2059, we days that were...
Abstract cGAS‐STING signalling is induced by detection of foreign or mislocalised host double‐stranded (ds)DNA within the cytosol. STING acts as major hub, where it controls production type I interferons and inflammatory cytokines. Basally, resides on ER membrane. Following activation traffics to Golgi initiate downstream subsequently endolysosomal compartments for degradation termination signalling. While known be degraded lysosomes, mechanisms controlling its delivery remain poorly...
There are no pharmacological disease-modifying treatments with an enduring effect to mitigate the seizures and comorbidities of established chronic temporal lobe epilepsy (TLE). This study aimed evaluate for disease modifying effects sodium selenate treatment in chronically epileptic rat post-status epilepticus (SE) model drug-resistant TLE. Wistar rats underwent kainic acid-induced SE or sham. Ten-weeks post-SE, animals received selenate, levetiracetam, vehicle subcutaneousinfusion...
Background The Chinese Great Famine caused widespread starvation in 1959–1961. Its long-term association with depressive symptoms has not been studied. Aims To estimate the burden of and famine exposure symptoms. Method China Health Retirement Longitudinal Study is a nationwide representative survey 17 708 adults aged ≥45. Propensity score matching modified Poisson regression were used to evaluate between self-reported early life among overall participants. Such associations also assessed by...
The aim of the study was to specify prevalence and severity menopausal symptoms among middle-aged women understand factors associated with women’s perimenopausal healthcare-seeking behavior in Shanghai, China. A community-based cross-sectional carried out involving 3147 participants aged 40–60 years. combination stratified sampling quota used. Out total 16 districts 7 were purposefully selected consideration covering both central suburban areas, population distribution, willingness...
Containerization is the mainstream of current software development, which enables to be used across platforms without additional configuration running environment. However, many images created by developers are redundant and contain unnecessary code, packages, components. This excess not only leads bloated that cumbersome transmit store but also increases attack surface, making them more vulnerable security threats. Therefore, image slimming has emerged as a significant area interest....
To investigate the differences of clinical characteristics and treatment outcomes between paraneoplastic neurologic syndrome (PNS) patients with one high-risk antibody two antibodies. We retrospectively analyzed data 51 PNS antibody. Clinical were extracted from patients' electronic medical records. presentations, cerebrospinal fluid (CSF) parameters, radiological antibodies analyzed. 41 1 10 2 enrolled in this study. It was found that psychobehavioral abnormality (OR = 11.327, 95% CI: 1.371...
Perinatal testicular torsion is not common in clinic. We report our experience treating such a condition 50-day boy with an intraperitoneal mass. The clinical manifestations, physical examination, imaging examination and treatment of the were retrospectively analyzed related literatures reviewed. Laparoscopic exploration, resection abdominal mass, high ligation left processus vaginalis orchiopexy performed after admission. According to results intraoperative frozen-section paraffin section...
Cognitive impairments have been reported in patients with hyperprolactinemia; however, there is a lack of knowledge brain structure alterations relevant to hyperprolactinemia prolactinomas. Thus, we aimed identify changes prolactinomas and determine whether these are related cognitive performance clinical characteristics.Participants were 32 female 26 healthy controls (HC) matched for age, sex, education, handedness. All participants underwent magnetic resonance imaging scans,...
A history of mild traumatic brain injury (mTBI) is linked to a number chronic neurological conditions, however there still much unknown about the underlying mechanisms. To provide new insights, this study used clinically relevant model repeated mTBI in rats characterize acute and neuropathological neurobehavioral consequences these injuries. Rats were given four sham-injuries or mTBIs allocated 7-day 3.5-months post-injury recovery groups. Behavioral analysis assessed sensorimotor function,...
Highlights•Crat in AgRP neurons helps nutrient replenishment as food is available after fasting•Crat maintain appropriate hepatic glucose production during facilitates peripheral substrate switching upon acute refeeding•Crat regulates protein expression and acetylation cells fasting refeedingSummaryAgRP control utilization partitioning conditions of energy deficit replenishment, although the molecular mechanism unknown. We examined whether carnitine acetyltransferase (Crat) affects...
p16 INK4 and RB1 are two potent cell cycle regulators to control the G1/S transition by interacting with CDK4/6, E2F, D-type cyclins, respectively. Depending on tumour type, genetic alterations resulting in functional inactivation have frequently been reported both genes. By contrast, much less is known regarding overexpression of these proteins tumor cells. In this study, expressions RB1, CDKN2A copy number variances (CNV) cells were assessed immunohistochemistry fluorescence situ...