A5070377534- RNA modifications and cancer
- Kidney Stones and Urolithiasis Treatments
- Cancer-related molecular mechanisms research
- RNA Research and Splicing
- Pediatric Urology and Nephrology Studies
- Urinary Bladder and Prostate Research
- Paleopathology and ancient diseases
- Renal cell carcinoma treatment
- MicroRNA in disease regulation
- Cancer, Lipids, and Metabolism
- Urinary and Genital Oncology Studies
- Cancer-related gene regulation
- Bladder and Urothelial Cancer Treatments
- Wireless Body Area Networks
- Remote Sensing and LiDAR Applications
- Blood Pressure and Hypertension Studies
- Ferroptosis and cancer prognosis
- Kruppel-like factors research
- Wireless Communication Security Techniques
- Smart Grid Security and Resilience
- Cassava research and cyanide
- Mycotoxins in Agriculture and Food
- Prostate Cancer Diagnosis and Treatment
- Medicinal Plants and Neuroprotection
- Molecular Biology Techniques and Applications
Shenyang Ligong University
2020-2024
Institute of Plant Protection
2024
Hebei Medical University
2018-2024
Second Hospital of Hebei Medical University
2018-2024
Yangtze University
2024
Chinese Academy of Agricultural Sciences
2024
University Hospital Bonn
2017-2020
Tongji Hospital
2015-2018
Huazhong University of Science and Technology
2011-2018
This paper investigates the state estimation problem for linear time-invariant systems where sensors and controllers are connected by a stationary memoryless digital communication channel. Time delay, packet dropout, data rate limitation occur simultaneously in such We discuss observability of under constraints. A real-time transport protocol (RTP) is used transmission. quantization, coding, control scheme on basis RTP proposed order to overcome difficulties. Sufficient conditions provided...
In various malignancies RNA fragments are dysregulated. Our study was designed to determine the expression of 4, 5'-tRNA halves in tissue and serum patients with clear cell renal carcinoma.Tissue samples carcinoma nonmalignant disease were collected prospectively our biobank. We isolated total from 95 carcinomas 50 normal tissues as well 27 13 urological disease. To specifically we dephosphorylated ligated an adaptor nucleotide 3' end tRNA halves. The levels (5'-tRNA-Arg-CCT,...
Abnormal regulation of gene expression results in the malignant proliferation bladder cancer (BC) cells. We previously demonstrated that NPL4 upregulation promotes BC progression; however, its regulatory and functional mechanisms on downstream genes remain unknown. Transcriptome sequencing reverse transcription-quantitative polymerase chain reaction were used to identify confirm METTL11A as a NPL4. Protein interactions detected through co-immunoprecipitation assays. Cell growth tumor...
Abstract Splicing factor 3B subunit 4 (SF3B4) plays important functional roles not only in pre-mRNA splicing, but also the regulation of transcription, translation, and cell signaling, its dysregulation contributes to various diseases including Nager syndrome tumorigenesis. However, role SF3B4 underlying mechanisms clear renal carcinoma (ccRCC) remain obscure. In present study, we found that expression was significantly elevated ccRCC tissues negatively correlated with overall survival...
Abstract Oxidative Balance Scores (OBS) are utilized to assess an individual's antioxidant status, encompassing both dietary and lifestyle factors that contribute oxidative balance. This study investigates the relationship between OBS chronic kidney disease (CKD) prevalence among U.S. adults, utilizing data from National Health Nutrition Examination Survey (NHANES) 2007–2018. The involved a cross-sectional analysis of 13,373 individuals NHANES, focusing on adults aged 20 years or older. was...
Non-coding RNAs play an important role in human carcinogenesis. YRNAs (Ro-associated Y), a novel class of non-coding RNAs, have been identified as biomarker various malignancies, but remain to be studied urinary bladder cancer (BCA) patients. The expression all four (RNY1, RNY3, RNY4, RNY5) was determined archival BCA (urothelial carcinoma, n = 88) and normal urothelial (n 30) tissues using quantitative real-time PCR. Associations with clinicopathological parameters prognostic for overall...
RNA-binding motif protein 24 (RBM24) acts as a multifunctional determinant of cell fate, proliferation, apoptosis, and differentiation during development by regulating premRNA splicing mRNA stability. It is also implicated in carcinogenesis, but the functions RBM24 bladder cancer (BC) remain unclear. In present study, we revealed that was upregulated BC tissues. Importantly, found higher level correlated with poor prognosis patients. Overexpression promoted while depletion inhibited...
The treatment of bilateral complex renal stones is a tough challenge for urologists. This study aimed to evaluate the efficiency and safety ultrasonography-guided multi-tract percutaneous nephrolithotomy (PCNL) combined with EMS lithotripsy such cases.Twenty-seven patients suffering from calculi underwent t PCNL. PCNL began establishment nephrostomy access, which was achieved under ultrasound guidance followed by stone fragment removal lithotripsy. same processes were then performed on...
GDP-mannose transporters (GMTs) have been implicated in the virulence of some important pathogenic fungi, and guanosine diphosphate (GDP) mannose transport from cytosol to Golgi lumen prior mannosylation, where attaches modified protein. GMTs could be potential targets for new antifungal drugs, as disruption any step biosynthesis can affect fungal viability, growth, or virulence. To date, transporter has extensively studied yeast, but its biological function particularly F. graminearum, is...
This paper considers Cyber-Physical Systems (CPSs) in the presence of Denial-of-Service (DoS) attacks, and investigates networked control problem under data rate limitations. We develop a framework for CPSs DoS present state-estimate scheme attacks. For different communication status, information on plant state is transmitted to controller by employing order mitigate influence Sufficient conditions mean square observability stabilization are derived applying theoretic tools source coding....
Utilization of airborne Inverse-Synthetic-Aperture-Radar (ISAR) for detection moving targets on the sea surface is studied in this paper. In order to systematically analyze characterization radar imaging presence both motion and observation uncertainty a target, study incorporates Bayes-PRM multi-query algorithm fusing ISAR multi-sensing information. The isochronously samples physical quantities, such as UAV position, altitude, pitch angle, velocity sequence multivariate groups, converts...
Substrate reduction therapy with analogs reduces the accumulation of substrates by inhibiting metabolic pathways involved in their biosynthesis, providing new treatment options for patients primary hyperoxalurias (PHs) that often progress to end-stage renal disease (ESRD). This research aims evaluate inhibition efficacy Hydroxy-L-proline (HYP) against calcium oxalate (CaOx) crystal formation Drosophila Melanogaster (D. Melanogaster) comparing them Pyridoxine (Vitamin B6). Three stocks (W118,...
BACKGROUND Hydroxycitric acid is a potential lithontriptic agent for calcium oxalate (CaOx) stones in the kidneys. This study aimed to evaluate safety and efficiency of hydroxycitric tripotassium (K-HCA) against CaOx crystal formation using Drosophila melanogaster hyperoxaluria models. MATERIAL AND METHODS Wild-type D. were fed standard medium with ethylene glycol or sodium added induce hyperoxaluria. Their Malpighian tubules dissected observed under microscope every 3 days. Crystal deposit...
To evaluate the efficiency and safety of paravertebral block (PVB) as single main anesthesia for unilateral mini-invasive percutaneous nephrolithotomy (PCNL).Forty-five American Society Anesthesiologists grade I/II/III patients with large upper urinary tract stones were included in our retrospective study. All received multilevel PVB from T10 to L1 10 mL 0.5% ropivacaine each segment. After was confirmed, PCNL performed. Intraoperative postoperative pain management associated adverse events...
To evaluate the safety and efficacy of retroperitoneal laparoscopic ureterolithotomy (RLU) in treatment proximal ureteral stones accompanied with obstructive pyelonephritis without preoperative drainage. We retrospectively reviewed 21 cases infected kidney undergoing RLU between July 2013 September 2016. Stone-induced hydronephrosis was diagnosed using blood urine tests imaging modalities. Empirical effective broad spectrum antibiotic therapy initiated immediately, then urgent performed...