A5015148931- Esophageal Cancer Research and Treatment
- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer, Hypoxia, and Metabolism
- Inflammatory Biomarkers in Disease Prognosis
- Cancer-related molecular mechanisms research
- Medical Imaging Techniques and Applications
- Ferroptosis and cancer prognosis
- Circular RNAs in diseases
- Ureteral procedures and complications
- Renal cell carcinoma treatment
- Helicobacter pylori-related gastroenterology studies
- Immune Cell Function and Interaction
- Gastric Cancer Management and Outcomes
- Gallbladder and Bile Duct Disorders
- Lymphoma Diagnosis and Treatment
- Asthma and respiratory diseases
- Hepatocellular Carcinoma Treatment and Prognosis
- MicroRNA in disease regulation
- Pelvic floor disorders treatments
- Respiratory and Cough-Related Research
- Viral-associated cancers and disorders
- Urinary Tract Infections Management
- Medical Imaging and Pathology Studies
Guangxi Academy of Sciences
2025
Icahn School of Medicine at Mount Sinai
2023-2024
West China Hospital of Sichuan University
2017-2024
Soochow University
2024
First Affiliated Hospital of Soochow University
2024
Zhengzhou University
2023-2024
Sichuan University
2017-2024
Henan Provincial People's Hospital
2024
Northwest A&F University
2024
Harbin Medical University
2013-2023
Background: Primary pulmonary lymphoepithelioma-like carcinoma (LELC) is a rare subtype of non-small cell lung cancer (NSCLC), and no effective treatments have been defined for advanced disease. Programmed death-ligand 1 (PD-L1) expressed in group cancers that may be suitable targets specific immunotherapy. Methods: This study investigated the expression clinical value PD-L1 LELC. Seventy-nine patients with LELC were investigated. Paraffin-embedded tumor sections stained antibody....
// Qipeng Fan 1 , Qingchun Cai Pengfei Li 1, 2 Wenyan Wang 3 Jing 4 Emily Gerry 5 Tian-Li Ie-Ming Shih Kenneth P. Nephew 6 and Yan Xu Department of Obstetrics Gynecology, Indiana University School Medicine, Indianapolis, IN 46202, USA Pharmaceutical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, P.R. China The Second Hospital Anhui Hefei City, 230601, MASDINO (Beijing) Co. Ltd., 100123, Pathology, Johns Hopkins Baltimore, MD 21231, Sciences, Jordan...
Background: To evaluate the clinical significance of degree pulmonary fissure completeness (PFC) on major in-hospital outcomes following video-assisted thoracoscopic (VATS) lobectomy for non-small-cell lung cancer (NSCLC). Materials and methods: We carried out a single-center retrospective analysis prospectively maintained database at our unit between August 2014 October 2015. Patients were divided into two groups based their sum average (FSA). with FSA >1 (1< ≤3) considered to have...
Primary pulmonary lymphoepithelioma-like carcinoma (LELC) is a rare type of non-small cell lung cancer. In this study, we retrospectively reviewed the data from 74 consecutive patients with LELC and investigated prognostic value pretreatment monocyte-to-lymphocyte ratio (MLR). The cut-off determined by ROC curve for MLR was 0.262. According to value, 36 (48.6%) had lower (<0.262) at diagnosis. There no significant correlation between level gender, age, smoking history, stage, lactate...
Esophageal squamous cell carcinoma (ESCC) is one of the most fatal cancers with high morbidity and mortality, which severely affects people's lives. Long intergenic non-protein coding RNA 858 (LINC00858) was confirmed to promote progression colorectal cancer lung cancer. However, role lncRNA LINC00858 still unknown in ESCC. Herein, main purpose research explore function its impact on ESCC biological behaviors. RT-qPCR used test expression LINC00858, miR-425-5p ABL proto-oncogene 2 (ABL2)...
Background/Aims: Thymic stromal lymphopoietin (TSLP) is a cytokine that plays diverse roles in the regulation of immune responses. However, detailed understanding TSLP signaling pathway asthma remains elusive. In this study, we aimed to investigate role and its effect on airway inflammation remodeling. Methods: Forty Sprague Dawley (SD) rats were evenly classified into control, asthma, IgG2a mAb anti-TSLP groups. Ovalbumin (OVA)-induced models successfully established. Blood, bronchoalveolar...
The incidence of gastric cancer worldwide, and in particular developing countries, has shown a marked increase. Poor prognosis patients occurs due to the rapid metastasis disease via lymphatic blood vessels. aim this study was investigate expression clinical significance D2-40 CD34 human cancer. wasdetected 1,072 cases Chinese with carcinoma using immunohistochemistry. vessel density (LVD) microvessel (MVD) were calculated analyzed correlation clinicopathological factors determined. LVD MVD...
The objective of the present study was to investigate association B7-H3 expression and cluster differentiation (CD)163+ tumor-associated macrophage (TAM) infiltration with clinicopathological parameters in urothelial cell carcinoma bladder (UCB), their potential conjoint effects on progression UCB. CD163+ TAM tumor specimens from 134 consecutive patients that underwent radical cystectomy for UCB were tested using immunohistochemistry, followed by statistical analysis. In these patients,...
Gallbladder adenocarcinoma is the main histopathological type of gallbladder cancer (GBC), so it particularly important to understand its biological characteristics. Due low incidence this cancer, there are few studies with large sample sizes. The log positive lymph nodes (LODDS) has been evaluated by many scholars as a node stage that may play better role than 8 th edition American Joint Committee on Cancer (AJCC) staging system in cancers. However, effect LODDS not proven adenocarcinoma....
Abstract Introduction Perioperative urinary tract infections (PUTIs) are common in the United States and a significant contributor to high healthcare costs. There is lack of large studies on risk factors for PUTIs after total hysterectomy (TH). Methods We conducted retrospective study using national inpatient sample (NIS) 445,380 patients from 2010 2019 analyze annual incidence associated with TH perioperatively. Results were found 9087 overall, showing 2.0% incidence. substantial...
The Mandarin Chinese version of the Leicester Cough Questionnaire (LCQ-MC) is a symptom specific questionnaire designed to assess impact cough severity, major postoperative patients undergoing lung resection cough. aim this study validate LCQ-MC in with operation.Totally 121 undergone operation single medical team, from September 2015 April 2016 Thoracic Surgery Department West China hospital Sichuan University, were investigated by before and after operation. We analyzed calculated...
Colorectal cancer (CRC) is the third most common all around world, and it seriously threats human health. PHF19 has been proved to be closely related prognosis of patients in a variety malignant tumors, but effect on evaluation CRC not confirmed.In our study, we used GEO, TCGA database IHC verify expression samples. Survival analysis based TCGA, GEO series, own sample were performed. Cox regression was performed reveal relationship between prognosis. Co-expression find genes expression....
This study aimed to compare the predictive efficacy of four different lymph node (LN) staging systems on overall survival (OS) patients with surgically resected perihilar cholangiocarcinoma (pCCA), and construct a novel prognostic nomogram predict OS in pCCA patients.Patients that underwent surgical resection between 2004 2016 were selected from Surveillance, Epidemiology, End Results (SEER) database (n=1,173). Patients randomly divided into modeling cohort an internal verification cohort....
Polymorphisms in the gene encoding for A disintegrin and metalloprotease 33 (ADAM33) are closely associated with risk of bronchial asthma attacks different populations. We collected blood samples from 248 patients – 130 Han ethnic group 118 Mongolian living Inner Mongolia region China, analyzed single nuclear polymorphisms (SNPs) T1, T2 V4 loci ADAM33 using PCR-RFLP (restriction fragment length polymorphism). In addition, we also tested 256 healthy controls (134 122 groups respectively) same...
Abstract Background Kinetic estimation provides fitted parameters related to blood flow perfusion and fluorine-18-fluorodeoxyglucose ( 18 F-FDG) transport intracellular metabolism characterize hepatocellular carcinoma (HCC) but usually requires 60 min or more for dynamic PET, which is time-consuming impractical in a busy clinical setting has poor patient tolerance. Methods This study preliminarily evaluated the equivalence of liver kinetic between short-term (5-min data supplemented with...