A5100703718- Cultural Industries and Urban Development
- Cancer-related molecular mechanisms research
- Cancer Genomics and Diagnostics
- Pregnancy and preeclampsia studies
- Pancreatic and Hepatic Oncology Research
- Advanced Computing and Algorithms
- Healthcare and Venom Research
- Psychoanalysis and Social Critique
- Genetics, Aging, and Longevity in Model Organisms
- Microbial metabolism and enzyme function
- Lung Cancer Treatments and Mutations
- HER2/EGFR in Cancer Research
- Ziziphus Jujuba Studies and Applications
- Retinal and Optic Conditions
- Hedgehog Signaling Pathway Studies
- Cytokine Signaling Pathways and Interactions
- Macrophage Migration Inhibitory Factor
- Advanced Vision and Imaging
- Genetic factors in colorectal cancer
- Hydrogels: synthesis, properties, applications
- Advanced Polymer Synthesis and Characterization
- Cancer Immunotherapy and Biomarkers
- Retinal Imaging and Analysis
- Nicotinic Acetylcholine Receptors Study
- TGF-β signaling in diseases
Southwest Hospital
2018-2025
Gansu Provincial Hospital of TCM
2024
Army Medical University
2018-2024
Nanjing Brain Hospital
2017-2023
Nanjing Medical University
2014-2023
Huaian First People’s Hospital
2014-2022
Xuzhou Medical College
2019
Second People’s Hospital of Huai’an
2019
Shanghai Academy of Social Sciences
2011-2012
Sichuan University
2008
Combining whole exome sequencing, transcriptome profiling, and T cell repertoire analysis, we investigate the spatial features of surgically-removed biopsies from multiple loci in tumor masses 15 patients with non-small lung cancer (NSCLC). This revealed that immune microenvironment has high heterogeneity such intratumoral regional variation is as large inter-personal variation. While local total mutational burden (TMB) associated T-cell clonal expansion, anti-tumor cytotoxicity does not...
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Previous studies have suggested that abnormal expression of BMP-4, BMP-7, and BMP-9 correlated with tumor progression in HCC, but role played by BMP-2 HCC has not yet been reported. To determine we first investigated effect exogenous on growth cell lines SK-Hep-1, Hep G2, 3B. Next, studied function SK-Hep-1 line using a recombinant lentivirus vector to deliver BMP-2. We also used siRNA silence endogenous 3B line. Then,...
Abstract Introduction Cognitive impairment is the core symptom of schizophrenia, significantly impacting functional outcome. Improvement cognitive function has been an important aspect treatment schizophrenia. Therefore, this study to demonstrate effects first‐generation antipsychotic haloperidol, second‐generation olanzapine and ziprasidone, alpha‐7 nicotinic acetylcholine receptor agonist PHA ‐543613 on spatial learning memory. Material Methods C57 BL /6 mice received intraperitoneal...
Abstract Aim Liquid biopsy shows great potential in the fields of early diagnosis and prognosis cancer. Ovarian cancer (OC) is seventh most common eighth cause death from women. The OC vital for subsequent treatment outcome. Here we investigated two markers: cell‐free DNA concentration (cfDNA conc) integrity (cfDI) between patients healthy controls. Methods Age‐matched controls were enrolled this study. In total, there are 20 cfDNA conc cfDI calculated by arthrobacter luteus (ALU) gene using...
Long noncoding RNAs (lncRNAs) have been reported as critical modulators in many diseases including preeclampsia. Since the association between lncRNA BNIP3P1 and its cognate gene BNIP3 preeclampsia has revealed previously, this study aimed to further explore function mechanism of EdU TUNEL assays that or overexpression inhibited trophoblast cell proliferation enhanced apoptosis As suggested by western blot analysis, protein levels apoptotic markers cells were affected overexpression. The...
This paper introduces Professor