A5101994003- Reproductive System and Pregnancy
- Ferroptosis and cancer prognosis
- Endometriosis Research and Treatment
- Nosocomial Infections in ICU
- Chemical Analysis and Environmental Impact
- Fungal Infections and Studies
- Reproductive Health and Technologies
- Gynecological conditions and treatments
- Infection Control in Healthcare
- Uterine Myomas and Treatments
- Ovarian function and disorders
- Mercury impact and mitigation studies
- Phagocytosis and Immune Regulation
- Antifungal resistance and susceptibility
- Building Energy and Comfort Optimization
- Cancer-related molecular mechanisms research
- Hippo pathway signaling and YAP/TAZ
- Cancer Mechanisms and Therapy
- Hepatitis B Virus Studies
- Reproductive Biology and Fertility
- Infection Control and Ventilation
- Cardiovascular Health and Risk Factors
- Antibiotic Resistance in Bacteria
- Plant Toxicity and Pharmacological Properties
- Respiratory Support and Mechanisms
Jiangxi Maternal and Child Health Hospital
2021-2025
Henan Normal University
2025
Shandong First Medical University
2023-2025
Shandong Tumor Hospital
2023-2025
Anhui Jianzhu University
2024
Huashan Hospital
2023-2024
Fudan University
2023-2024
Guangxi University
2024
Shanghai Medical College of Fudan University
2024
Hebei University of Chinese Medicine
2020-2023
Abstract Background Nosocomial infections (NIs) are an important cause of mortality, and increasing evidence reveals that the prevalence NIs can be reduced through effective prevention control measures. The aim this study was to investigate impact measures for COVID-19 pandemic on NIs. Methods A retrospective conducted analyze before after 6 months in Children’s Hospital Soochow University. Results total 39,914 patients 2019 34,645 2020 were admitted hospital during study. There 1.39%...
Summary The increasing incidence of vulvovaginal candidiasis ( VVC ) and the emergence fluconazole resistance are an indisputable fact. However, little information is available regarding correlation between in vaginal Candida albicans expression drug efflux pump genes. In this study, we investigated species distribution, susceptibility profiles mechanisms strains. total, 785 clinical isolates were collected from patients with . C. was most frequently isolated n = 529) followed by glabrata...
Abnormal lipid deposition in the progress of diabetic nephropathy (DN) plays an important role a number studies that have shown SGLT2 inhibitor (SGLT2i) empagliflozin metabolism, but its mechanism is still unclear.We aimed to explore effect on levels kidney cancer patients with DN and postoperative without carcinoma; showed ectopic deposition. In type 2 diabetes model mice induced by streptozotocin (STZ) high-fat diet, combined AMPK plus or compound C was applied, followed analyses blood,...
The prevalence of drug-resistant bacteria is a major challenge throughout the world, especially with respect to Gram-negative bacteria, such as Acinetobacter baumannii, which are regarded greatest bacterial threat human health by World Health Organization (WHO). In this work, 1,3,4-thiadiazole was introduced into main skeleton classical peptidomimetic peptide deformylase (PDF) inhibitor in pursuit highly efficient and broad-spectrum bacteriostatic drugs. Upon detailed structure–activity...
Background The role of sperm DNA fragmentation index (DFI) in fertility remains controversial. Herein, we analyzed its association with semen parameters, embryonic development, and pregnancy outcomes after vitro fertilization (IVF) treatment. Additionally, assessed whether DFI had a potential impact on long-term maternal neonatal complications. Methods A total 5,271 women who underwent IVF treatment for the first time between October 1, 2020, July 31, 2023, were included from an academic...
Globally, breast cancer is among the most frequent cancers, and tumor progression greatly impacted by immune system. Studies have revealed a correlation between phenotypes of cells incidence cancer; nevertheless, causal relationship has yet to be fully elucidated. Hence, we sought ascertain cell subtypes through implementation Mendelian randomization (MR). MR analysis utilized freely available genetic data explore causation link 731 susceptibility cancer, distinguishing estrogen...
Loss of FXR, one bile acid receptors, enlarged livers. Yes-associated protein 1 (YAP1), a dominant oncogene, promotes hepatocellular carcinoma (HCC). However, the relationship between FXR and YAP1 was unspecified in homeostasis HCC. Here, we used TIMER2.0, Cancer Genome Atlas (TCGA) Database, Kaplan–Meier Plotter Database discovered that positively correlated with better prognosis liver cancer patients. Our previous research showed dihydroartemisinin (DHA) inhibited cell proliferation HepG2...
Abstract Rasagiline mesylate is a highly potent, selective and irreversible monoamine oxidase type B (MAOB) inhibitor effective as monotherapy or adjunct to levodopa for patients with Parkinson's disease (PD). However, few studies have evaluated the efficacy safety of rasagiline in Chinese population. This study was designed investigate adjunctive therapy treatment PD patients. randomized, double-blind, placebo-controlled, parallel-group, multi-centre trial conducted over 12-wk period that...
Silicone rubber insulators are widely used in power grids because of their excellent performance, but aging has been an inevitable problem silicone rubber, especially extreme conditions, such as acidic conditions. In order to clarify the performance changes environment, this paper uses developed acid-resistant sheet and common samples research objects, conducts comparison test on them a natural environment. The electrical properties, physical chemical properties two types specimens with...
Background: A decline in adolescent health holds significant repercussions for public health. Promoting exercise is essential to improve physical and mental among youth. This study aimed explore the effect of CrossFit training programs on sociogenic somatic anxiety adolescents. Methods: In March 2023, 100 adolescents were openly recruited from eight middle schools Jinhua, China. The participants, divided equally into control experimental groups, experienced either traditional or training,...
Metabolic reprogramming has been identified as a core hallmark of cancer. Solute carrier family 2 is major glucose family. It consists 14 members, and we mainly study solute member 1 (SLC2A1) (SLC2A2) here. SLC2A1, existing in human erythrocytes, brain endothelial cells, normal placenta, was found to be increased hepatocellular carcinoma (HCC), while SLC2A2, the transporter liver, decreased HCC.To identify if SLC2A1 SLC2A2 were associated with immune infiltration addition participating...
Abstract Background Several surveys have reported that patients treated with gonadotropin-releasing hormone antagonist (GnRH-ant) protocol showed a significantly lower rate of implantation and clinical pregnancy compared to GnRH agonist (GnRH-a) during in vitro fertilization-fresh embryo transfer. Subsequent studies imputed this poor outcome the negative effects GnRH-ant on endometrial receptive. However, mechanisms were not fully understood. Methods The data 2815 undergoing fresh transfer...
The overall prevalence of hepatitis B virus (HBV) infection in China is declining. purpose this study was to use a community-based epidemiological update the status mountainous regions China, and evaluate impact Expanded Program Immunization (EPI) on HBV transmission. In total, 10,383 participants were selected by multi-stage stratified random cluster sampling two regions, Xianju Anji, Zhejiang province, China. positive rates surface antigen (HBsAg), anti-HBV core (anti-HBc), (anti-HBs)...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Zhang Z, Long S, Huang Tan J, Wu Q, O. Regulatory effect of daphnetin on the balance Th17 and Treg cells in peripheral blood mononuclear from patients with unexplained recurrent pregnancy loss. Central European Journal Immunology. 2020;45(4):403-408. doi:10.5114/ceji.2020.103414. APA Zhang, Z., Long, S., Huang, Tan, J., Wu, Q., & (2020). Immunology, 45(4), 403-408. https://doi.org/10.5114/ceji.2020.103414...
To investigate the regulatory mechanism of SCF expression in human GCs PCOS related follicles.SCF, BMP15 and HIF-1α were evaluated serums, follicular fluids (FFs) GCs, which collected from 69 patients 74 normal ovulatory patients. KGN cell line was used this study.Our results showed that rate MII oocyte 2PN fertilization lower group, though retrieved much more oocytes. The level FF serum also We found a weakened when compared with non-PCOS significantly increased cells after treating...