A5100350002- Radiation Detection and Scintillator Technologies
- Medical Imaging Techniques and Applications
- Nuclear Physics and Applications
- Particle Detector Development and Performance
- Astrophysics and Cosmic Phenomena
- Atomic and Subatomic Physics Research
- Gamma-ray bursts and supernovae
- Advanced Chemical Physics Studies
- Arctic and Antarctic ice dynamics
- Spectroscopy and Quantum Chemical Studies
- Radiation Therapy and Dosimetry
- Neutrino Physics Research
- Molecular spectroscopy and chirality
- GaN-based semiconductor devices and materials
- Climate change and permafrost
- Advanced Radiotherapy Techniques
- Ga2O3 and related materials
- Dark Matter and Cosmic Phenomena
- Neonatal and fetal brain pathology
- Cerebral Palsy and Movement Disorders
- Climate variability and models
- Oceanographic and Atmospheric Processes
- Semiconductor materials and devices
- Advanced X-ray and CT Imaging
- Optimism, Hope, and Well-being
Chinese Academy of Sciences
2016-2025
Wuhan University of Science and Technology
2024
China Resources (China)
2024
Anhui University of Traditional Chinese Medicine
2024
Ningbo Institute of Industrial Technology
2024
University of Chinese Academy of Sciences
2011-2024
Northwestern Polytechnical University
2024
Institute of High Energy Physics
2013-2023
First Institute of Oceanography
2016-2023
Ministry of Natural Resources
2021-2023
Abstract Immunotherapy shows promising therapeutic potential for long‐term tumor regression. However, current cancer immunotherapy displays a low response rate due to insufficient immunogenicity of the cells. To address these challenges, herein, intracellular‐acidity‐activatable dynamic nanoparticles eliciting by inducing ferroptosis cells are engineered. The engineered integrating an ionizable block copolymer and acid‐liable phenylboronate ester (PBE) covalent bonds tumor‐specific delivery...
Prefabricated building projects (PBPs) have gained worldwide popularity over the past few decades because of their various benefits. Supply chain management (SCM) is critical to successful delivery PBPs supply chains are complex, involving multiple processes and stakeholders. Poor SCM in causes cost overruns schedule delays. This study investigates production, transportation, assembly a PBP Hong Kong quantitatively analyze critique its SCM. Automated data collection technologies were adopted...
ConspectusMolecular mechanical force fields have been successfully used to model condensed-phase and biological systems for a half century. By means of careful parametrization, such classical can be provide useful interpretations experimental findings predictions certain properties. Yet, there is need further improve computational accuracy the quantitative prediction biomolecular interactions properties that depend on wave functions not just energy terms. A new strategy called explicit...
Advances in healthcare monitoring, human–machine interfaces, and soft robots require the development of wearable sensors that are efficient, scalable, facile to prepare. Although laser-induced graphene (LIG) has recently attracted considerable attention fabrication patterned graphene-based sensors, transfer process is inevitable due limited stretchability carbon precursors. In this work, we proposed a strategy for situ growth, transfer-free LIG on various flexible substrates...
Background: Remimazolam tosilate is a new ultra-short-acting benzodiazepine sedative medicine. In this study, we evaluated the effect of remimazolam on incidence hypoxemia during sedation in elderly patients undergoing gastrointestinal endoscopy. Methods: Patients group received an initial dose 0.1 mg/kg and bolus 2.5 mg tosilate, whereas propofol 1.5 0.5 propofol. ASA standard monitoring (heart-rate, non-invasive blood pressure, pulse oxygen saturation) entire examination process. The...
Abstract The 2013 Nobel Prize in Chemistry was awarded to the authors of first two publications utilizing concept combined quantum mechanical and molecular (QM/MM) methods. In celebrating this great event computational chemistry, we review early development QM/MM techniques associated events that took place through mid‐1990s. We also offer some prospects for future macromolecular systems.
In this letter, an enhancement-mode (E-mode) GaN p-channel field-effect transistors (p-FETs) with current density of −5.6 mA/mm and <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${I} _{{\mathrm {ON}}}/{I} {OFF}}}$ </tex-math></inline-formula> ratio 10 <sup xmlns:xlink="http://www.w3.org/1999/xlink">6</sup> was demonstrated on a p-GaN/AlN/AlGaN/GaN heterostructure Si substrate. A decent ohmic contact...
Abstract Pancreatic ductal adenocarcinoma (PDAC) is highly lethal and resistant to conventional therapies, including chemo‐, radio‐, immunotherapy. In this study, it first determined that a combination of dihydroartemisinin (DHA) RSL‐3 (a glutathione peroxidase 4 (GPX4) inhibitor) markedly induced ferroptosis PDAC tumor cells. A mechanistic study revealed DHA can react with iron ions generate carbon radicals deplete intracellular glutathione, thereby cumulatively triggering the lipid...
Dry eye disease (DED), a complex ocular surface with high prevalence rate, is associated corneal injury, excess oxidative stress and inflammation. Current therapeutic strategies, including artificial tears anti-inflammatory agents, are unable to address all the deleterious factors or achieve clinical cure due their temporary side effects. Here, we prepared multiple-functional eyedrop based on deposition of gold nanoparticles (AuNPs) reduced by ascorbic acid (AA) onto exosomal phospholipid...
Timing calibration is essential for positron emission tomography (PET) system as it enhances timing resolution to improve image quality. Traditionally, sources are employed calibration. However, the photons emitted by these travel in opposite directions, necessitating that positrons annihilate at multiple locations collect coincidence data across a greater number of lines response (LORs). To overcome this limitation, study proposes method utilising a60Co point source. The60Co source emits...
Improving the coincidence time resolution (CTR) of time-of-flight positron emission tomography (TOF-PET) systems to achieve a higher signal-to-noise ratio (SNR) gain or even direct imaging (dPEI) is paramount importance for many advanced new clinical applications PET imaging. This places demands on timing performance all aspects systems. One effective approach use microchannel plate photomultiplier tubes (MCP-PMTs) prompt Cherenkov photon detection. In this study, we developed dual-module...
<title>Abstract</title> The radiation imaging and intensity quantification of radioactive material is attracting increasing attention in numerous applications including radiological source investigation, safety, nuclear security, facility maintenance decommissioning. Here, quantitative measurement the far-field achieved by gamma-ray imaging, which based on conventional mask-antimask coded aperture approach. A multi-sensor system that fuses images, optical pictures, 3D point clouds into a...
In many areas, such as plains and gently undulating terrain, easy‐to‐measure soil‐forming factors landform vegetation do not co‐vary with soil conditions across space to the level that they can be effectively used in digital mapping. A challenging problem is how develop a new environmental variable co‐varies spatial variation under these situations. This study examined idea change patterns (dynamic feedback patterns) of land surface, those captured daily by remote sensing images during short...
Bioinert polymethylmethacrylate (PMMA) bone cement is the most conventional approach for quick fixation of orthopedic implant during hip replacement surgery. However, problems with loosening occur frequently and particularly under osteoporosis due to inadequate osteointegration between host bone. In order enhance ability PMMA cement, mineralized collagen (MC) was incorporated into (PMMA-MC) in current study. An improved wettability dynamic mechanical performance PMMA-MC demonstrated vitro,...
This study examined loneliness and future orientation as predictors of suicidal risk, namely, depressive symptoms suicide ideation, in a sample 228 college students (54 males 174 females). Results regression analyses indicated that was significant predictor both indices risk. The inclusion found to significantly augment the prediction model even after accounting for loneliness. Noteworthy, beyond orientation, Loneliness × Future Orientation interaction term further models Consistent with...
The explicit polarization (X-Pol) method is a fragment-based quantum mechanical model, in which macromolecular system or other large complex solution partitioned into monomeric fragments. present study extends the original X-Pol method, where all fragments are treated using same electronic structure theory, to multilevel representations, called X-Pol, different methods used describe has been implemented locally modified version of Gaussian 09. A key ingredient that couple interfragment...
A fragment-based variational many-body (VMB) expansion method is described to directly account for exchange repulsion, charge delocalization (charge transfer) and dispersion interactions in the explicit polarization (X-Pol) method. The present VMB/X-Pol approach differs from other fragment molecular orbital (FMO) techniques two major aspects. First, wave function monomeric system variationally optimized using standard X-Pol method, as opposed iterative update procedure adopted FMO. Second,...
A projected hybrid orbital (PHO) method was described to model the covalent boundary in a quantum mechanical and molecular (QM/MM) system. The PHO approach can be used ab initio wave function theory density functional with any basis set without introducing system-dependent parameters. In this method, secondary on atom is introduced formulate of atomic orbtials. primary for QM subsystem onto yield representation that provides good approximation electron-withdrawing power balance electronic...
Landsat satellites have the longest history of making global-scale Earth observations at medium spatial resolution any series and been widely used in various remote-sensing fields. However, many applications, including large-area or long-term land-cover monitoring, need reflectance data that had accurate atmospheric correction carried out. In this research, a MODIS-based per-pixel procedure was developed employed to produce surface (SR) product. A total 510 Landsat-8 Operational Land Imager...
The inclusion of exchange repulsion terms in the explicit polarization (X-Pol) model is examined by antisymmetrizing X-Pol Hartree product wave function; this yields with full eXchange, called X-Pol-X. When monomers are treated Hartree−Fock theory, calculation can be accomplished using formalism block-localized functions (BLW) that has been used a variety applications. In case structure X-Pol-X function allows for decomposition Fock matrix dimension M blocks into smaller matrices. method...
Three cyclonerane sesquiterpenoids, including the known cyclonerodiol (1), together with its new derivatives, (10E)-12-acetoxy-10-cycloneren-3,7 -diol (2) and 12-acetoxycycloneran-3,7-diol (3) were isolated from cultures of marine-sediment-derived fungus Trichoderma harzianum P1-4. The structures compounds (2 3) elucidated based on extensive spectroscopic methods (1D/2D NMR HR-MS) optical rotation analysis.
Lupus nephritis (LN) is a crucial complication of systemic lupus erythematosus (SLE) and has important clinical implications in guiding treatment. N-glycosylation immunoglobulin G (IgG) plays key role the development SLE by affecting balance anti-inflammatory proinflammatory responses. This study aimed to evaluate performance IgG for diagnosing LN sample female patients.This case-control recruited 188 women with SLE, including 94 patients age-matched without LN. The profiles plasma N-glycans...