- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Pediatric Hepatobiliary Diseases and Treatments
- Clinical Nutrition and Gastroenterology
- Liver Disease Diagnosis and Treatment
- Family Support in Illness
- Childhood Cancer Survivors' Quality of Life
- Renal Transplantation Outcomes and Treatments
- Drug Transport and Resistance Mechanisms
- Counseling, Therapy, and Family Dynamics
- Abdominal Surgery and Complications
- Child Therapy and Development
- Liver Diseases and Immunity
- Psychology, Coaching, and Therapy
- Family and Disability Support Research
- Gallbladder and Bile Duct Disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- Transplantation: Methods and Outcomes
- Non-Invasive Vital Sign Monitoring
- Diet, Metabolism, and Disease
- Globalization, Historical Perspectives, and International Relations
- Hernia repair and management
- Congenital Anomalies and Fetal Surgery
- Caveolin-1 and cellular processes
- Adolescent and Pediatric Healthcare
University Hospital Regensburg
2009-2024
Klinik und Poliklinik für Kinder- und Jugendmedizin
2008-2023
University Medical Center
2014
Uniwersytecki Szpital Dziecięcy
2014
University Hospital and Clinics
2014
University of Regensburg
2009-2012
Kinderklinik Regensburg
2009
Medizinische Hochschule Hannover
2000-2006
Genetic variants in the adenosine triphosphate‐binding cassette subfamily B member 4 ( ABCB4 ) gene, which encodes hepatocanalicular phosphatidylcholine floppase, can lead to different phenotypes, such as progressive familial intrahepatic cholestasis (PFIC) type 3, low phospholipid‐associated cholelithiasis, and of pregnancy. The aim this multicenter project was collect information on onset progression entity age groups assess relevance disease for differential diagnosis chronic liver...
ABSTRACT Background The development of graft fibrosis after pediatric liver transplantation (PLT) remains a major concern as it can lead to failure and ultimately loss. Elastography is non‐invasive method assess fibrosis, but its role in the posttransplant setting unclear. aim our study was evaluate shear wave elastography (SWE) assessment PLT, including split‐liver recipients. Methods We retrospectively analyzed data from PLT recipients who underwent surveillance biopsy concurrent 2D‐SWE...
OBJECTIVE:Comparison of the diagnostic findings MRI, CT and CEUS in children with benign malignant portal venous anomalies liver. MATERIALS/METHODS:Retrospective analysis CEUS, MRI scans 56 (age 0–17 years) a total 60 liver lesions vein/perfusion. All patients underwent using sulphur hexafluoride microbubbles multi-frequency probe (1–5 MHz, 6–9 MHz). Cine-loops were stored up to 3 minutes. was performed 38 lesions. 8 RESULTS:Out 49 (48 benign, 1 malignant), 9 vein/perfusion 2 biliary system...
Evaluation of the efficacy and safety Gelfoam for closure transhepatic or transsplenic parenchymal puncture tracts with large-bore sheaths in pediatric patients.Between January 2012 May 2013, 8 percutaneous accesses 3 were closed using patients. The primary study endpoints to determine treatment patient survival, technical success defined as successful tract without signs bleeding, complication rates. secondary occurrence local systemic inflammation.Overall survival was 100 % a median...
Abstract Background Portal vein complications (PVCs) after pediatric liver transplantation (LT) are sometimes asymptomatic, especially in the early phase, and can threaten both graft patient's survival. Therefore, purpose of this study is to analyze risk factors for portal thrombosis (PVT) stenosis (PVS) LT. Methods All patients ( n = 115) who underwent primary LT at Regensburg University Hospital between January 2010 April 2017 were included study. The pre‐, intra‐, postoperative parameters...
Abstract Background Pediatric liver transplantations generally represent advanced surgery for selected patients. In case of acute or chronic graft failure, biliary vessel complications, a retransplantation (reLT) can be necessary. these situations massive adhesions, critical patient condition lack good vessels anastomosis often are problematic. Methods Between 2008 and 2021, 208 pediatric patients received transplantation at our center. Retrospectively, all cases with least one were...
It is challenging for families to cope with the multifaceted stressors that arise when a child has undergone liver transplantation. The aim of present study was investigate how coping strategies can be supported by play-therapeutic interventions. Semistructured interviews parents 9 live- transplanted children were conducted. findings show interventions allowed liver-transplanted their illnesses and hospitalization more effectively. According parents’ perceptions, helped overcome fears;...
Background: Patients with an aortic aneurysm are at high cardiovascular risk. Pulse wave velocity (PWV) is used as a parameter for risk stratification but may be affected by disease (AoD). This study aimed to investigate the dependence of PWV on treated or untreated AoD and identify modifiable factors PWV. Methods: The measurement Mobil-O-Graph was performed fully automatically in collective 381 patients (75.6% male 24.4% female). Of all patients, 53.8% had nonaortic atherosclerotic vascular...
Abstract Background Intrahepatic arterial pseudoaneurysms are a rare, life-threatening complication after pediatric liver transplantation. Treatment of choice represents interventional radiological management with endovascular embolization the segmental artery proximal and distal to aneurysm. However, this technique results in loss perfusion aneurysm subsegment ischemia. Case presentation We report case 1-year-old girl pseudoaneurysm split-liver graft. Direct percutaneous, transhepatic...
Abstract Background After pediatric split liver transplantation, intra‐abdominal loss of domain due to large‐for‐size left lateral grafts is a frequent problem for fascial closure and potentially leads reduced perfusion abdominal compartment syndrome. Therefore, delayed with the use temporary silastic meshes reoperation or alternative bridging procedures are necessary. Methods Between March 2019 October 2021, biologic were used wall expansion in 6 cases transplantation. These analyzed...
Purpose: Retrospective analysis of the diagnostic accuracy and safety contrast enhanced ultrasound (CEUS) in children.
We present a systemic family and play therapeutic concept that was developed at the Childrens University Hospital in Eastern Bavaria (KUNO) to support children who had undergo liver transplant. The aims developing coping strategies deal with chronic disease. It includes six components: building trust diagnostics, stress reduction, disease, individual problems, everyday life normalisation, therapy parent coaching.
Die frühe postoperative Pfortaderthrombose stellt eine relativ häufige und schwere Komplikation nach Lebertransplantation bei Kindern dar. Das klinische Bild wird geprägt durch Zeichen der portalen Hypertension wie Aszites gastrointestinale Blutungen. Basistherapie ist die möglichst rasch einzuleitende Heparinisierung. Bei persistierender oder progredienter Thrombosierung bzw. persistierenden progredienten Symptomen operative Thrombektomie Retransplantation in Betracht zu ziehen. Beide...